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Impurities and reference standards

2-Fluoroaniline

Also known as o-Fluoroaniline, 1-Amino-2-fluorobenzene, 2-Fluorobenzenamine

CAS 348-54-9Formula C6H6FNMolar mass 111.12 g/molEC 206-478-9
GHS signal word: Danger. Pictograms: Flammable, Corrosive, Acute toxicity (severe), Harmful or irritant 39 suppliers listed
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2-Fluoroaniline chemical structure, C6H6FN, CAS 348-54-9
2D chemical structure

Key facts

What buyers check first

All properties
Physical form
Liquid
Melting point
-28.5 °C
Boiling point
175 °C
Density
1.1513 at 69.8 °F - Denser than water, will sink
Flash point
60 °C
HS code
292142
Category
Impurities and reference standards
UN number
UN 2941
Illustrative photo, 200 litre blue HDPE drums of liquid in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is 2-Fluoroaniline?

Plain description, key identifiers and synonyms

2-fluoroaniline is a derivative of aniline in which the hydrogen at position 2 has been substituted by fluorine. It is used as a pharmaceutical intermediate. It is a fluoroaniline and a primary arylamine.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-fluoroaniline
CAS number
348-54-9 CAS number cross-checkedOther or deprecated CAS: 99624-00-7
EC number
206-478-9
Molecular formula
C6H6FN
UNII
SE32ZK6617
MDL number
MFCD00007642
InChIKey
FTZQXOJYPFINKJ-UHFFFAOYSA-N
InChI
InChI=1S/C6H6FN/c7-5-3-1-2-4-6(5)8/h1-4H,8H2
SMILES (canonical and isomeric)
C1=CC=C(C(=C1)N)F

Synonyms

  • o-Fluoroaniline
  • 1-Amino-2-fluorobenzene
  • 2-Fluorobenzenamine
  • 2-fluorophenylamine
  • Benzenamine, 2-fluoro-
  • 2-Fluoro-phenylamine
  • Aniline, o-fluoro-
  • o-aminofluorobenzene
  • Aniline, 2-fluoro-
  • Telmisartan Impurity U
  • 2-fluoro-benzenamine
  • 2fluoroaniline
  • 2-flouroaniline
  • 2-fluoro aniline
  • 2-fluoro-aniline
  • 1lgw
  • 2-Fluoroaniline-
  • Ortho-fluoroaniline
  • 2-fluorobenzeneamine
  • (2-fluorophenyl)amine
  • 1,2-fluorobenzenamine
  • (2-fluorophenyl)-amine
  • 2-Fluoroaniline, >=99%
  • UN 2941
  • o-Fluoroaniline, 1-Amino-2-fluorobenzene
Show all 27 synonyms
  • 2-Fluoroaniline(Discontinued,See C4X-104762)
  • o-Fluoroaniline [UN2941] [Keep away from food]

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Physical form
Liquidexp.
Melting point
-28.5 °Cexp.
Boiling point
175 °Cexp.
Density
1.1513 at 69.8 °F - Denser than water, will sinkexp.
Flash point
60 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
111.12 g/molcalc.
Exact mass
111.0484 Dacalc.
LogP (octanol/water)
1.41calc.
Topological polar surface area
26.02 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
0calc.
Heavy atoms
8calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS02: Flammable
Flammable
GHS05: Corrosive
Corrosive
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H226Flammable liquid and vapour.
  • H301 + H311 + H331Toxic if swallowed. Toxic in contact with skin. Toxic if inhaled.
  • H301Toxic if swallowed.
  • H302Harmful if swallowed.
  • H311Toxic in contact with skin.
  • H315Causes skin irritation.
  • H317May cause an allergic skin reaction.
  • H318Causes serious eye damage.
  • H319Causes serious eye irritation.
  • H331Toxic if inhaled.
  • H335May cause respiratory irritation.
  • H341Suspected of causing genetic defects.

3 more on the safety page.

Precautionary statements (41)
  • P203Obtain, read and follow all safety instructions before use.
  • P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P233Keep container tightly closed.
  • P240Ground and bond container and receiving equipment.
  • P241Use explosion-proof electrical, ventilating and lighting equipment.
  • P242Use non-sparking tools.
  • P243Take action to prevent static discharges.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P262Do not get in eyes, on skin, or on clothing.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P303 + P361 + P353If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P316Get emergency medical help immediately.
  • P317Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P370 + P378In case of fire: Use appropriate media to extinguish.
  • P391Collect spillage.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P403 + P235Store in a well-ventilated place. Keep cool.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 2941

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

2-Fluoroaniline suppliers

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All 39 suppliers
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Where suppliers are based

39 suppliers in 8 countries

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2-Fluoroaniline price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Applications are not documented for this substance yet. Suppliers often describe uses on their product pages, linked in the suppliers list above.

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code 2-Fluoroaniline is traded under.

HS 2921.42Indicative HS code

Aniline derivatives and their salts

World exports in 2024
$495M
−2.5% vs 2023, imports $440M
2019 to 2024
Top exporters
  1. China69.8%
  2. India * partner reported19.6%
  3. Japan3.3%
Top importers
  1. Pakistan17.0%
  2. United Arab Emirates * partner reported12.7%
  3. Brazil10.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for 2-Fluoroaniline is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about 2-Fluoroaniline, based on the data on this page

What is 2-Fluoroaniline?

2-fluoroaniline is a derivative of aniline in which the hydrogen at position 2 has been substituted by fluorine. It is used as a pharmaceutical intermediate. It is a fluoroaniline and a primary arylamine.

What is the CAS number of 2-Fluoroaniline?

The CAS registry number of 2-Fluoroaniline is 348-54-9. Other or deprecated CAS numbers: 99624-00-7.

What is the molecular formula and weight of 2-Fluoroaniline?

The molecular formula of 2-Fluoroaniline is C6H6FN and its molar mass is 111.12 g/mol.

Is 2-Fluoroaniline hazardous?

2-Fluoroaniline carries the GHS signal word "Danger". Main hazards: flammable liquid and vapour, toxic if swallowed. toxic in contact with skin. toxic if inhaled, toxic if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of 2-Fluoroaniline?

2-Fluoroaniline is usually classified under HS code 292142 (Aniline derivatives and their salts). This is indicative, confirm it with your customs broker before shipping.

Where can I buy 2-Fluoroaniline?

CompoundList lists 39 suppliers of 2-Fluoroaniline in China, United States, India, Canada and 4 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy 2-Fluoroaniline in India?

3 suppliers in India list 2-Fluoroaniline on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of 2-Fluoroaniline?

Suppliers quote 2-Fluoroaniline on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle 2-Fluoroaniline

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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