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2-Methylaziridine chemical structure, C3H7N, CAS 75-55-8
2D chemical structure

Key facts

What buyers check first

Appearance
Colorless, oily liquid
Melting point
-65 °C
Boiling point
67 °C
Density
Relative density (water = 1): 0.8
Flash point
-3.9 °C
HS code
293399
Category
Pharmaceutical intermediates
UN number
UN 1921
Illustrative photo, clear liquid in a volumetric flask on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is 2-Methylaziridine?

Plain description, key identifiers and synonyms

2-Methylaziridine is a member of aziridines.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-methylaziridine
CAS number
75-55-8 CAS number cross-checked
EC number
200-878-7
Molecular formula
C3H7N
UNII
ULC972Q7TZ
MDL number
MFCD00005118
InChIKey
OZDGMOYKSFPLSE-UHFFFAOYSA-N
InChI
InChI=1S/C3H7N/c1-3-2-4-3/h3-4H,2H2,1H3
SMILES (canonical and isomeric)
CC1CN1

Synonyms

  • Propyleneimine
  • Propylenimine
  • Aziridine, 2-methyl-
  • Methylaziridine
  • 1,2-Propylenimine
  • 2-Methylethylenimine
  • Methylethylenimine
  • Propylene imine
  • 1,2-Propyleneimine
  • 2-Methylazacyclopropane
  • Propilenimina
  • RCRA waste number P067
  • DL-2-Methylaziridine
  • 2-methylethyleneimine
  • Propylene imine (inhibited)
  • 2-Methyl aziridine
  • Propyleneimine, inhibited
  • RCRA waste no. P067
  • 2-methylaziridine (propylenimine)
  • 2-methyl-aziridine
  • 5-20-01-00150 (Beilstein Handbook Reference)
  • UN 1921 (Salt/Mix)
  • Ozdgmoyksfplse-uhfffaoysa-
  • 2-?Methylaziridine (Propylenimine)
  • 2-Methylaziridine, (+/-)-
Show all 27 synonyms
  • 2-Methylaziridine, technical grade, 90%
  • Propyleneimine, inhibited [UN1921] [Flammable liquid]

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless, oily liquidexp.
Odour
Odor like aliphatic aminesexp.
Melting point
-65 °Cexp.
Boiling point
67 °Cexp.
Density
Relative density (water = 1): 0.8exp.
Flash point
-3.9 °Cexp.
Solubility
In water, miscible in all proportionsexp.
Vapour pressure
140 mm Hg at 25 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
57.10 g/molcalc.
Exact mass
57.0578 Dacalc.
LogP (octanol/water)
-0.02calc.
Topological polar surface area
21.94 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
0calc.
Heavy atoms
4calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1CN1

C1CN1

1 ring, 3 atoms, the Aziridine ring system.

720 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS02: Flammable
Flammable
GHS05: Corrosive
Corrosive
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H225Highly flammable liquid and vapour.
  • H300Fatal if swallowed.
  • H310Fatal in contact with skin.
  • H318Causes serious eye damage.
  • H330Fatal if inhaled.
  • H350May cause cancer.
  • H411Toxic to aquatic life with long lasting effects.
Precautionary statements (34)
  • P203Obtain, read and follow all safety instructions before use.
  • P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P233Keep container tightly closed.
  • P240Ground and bond container and receiving equipment.
  • P241Use explosion-proof electrical, ventilating and lighting equipment.
  • P242Use non-sparking tools.
  • P243Take action to prevent static discharges.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P262Do not get in eyes, on skin, or on clothing.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P303 + P361 + P353If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P316Get emergency medical help immediately.
  • P317Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P320Specific treatment is urgent (see supplemental first aid instructions on the label).
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
  • P370 + P378In case of fire: Use appropriate media to extinguish.
  • P391Collect spillage.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P403 + P235Store in a well-ventilated place. Keep cool.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 1921
Transport hazard class
3
Packing group
I

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

2-Methylaziridine suppliers

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Where suppliers are based

6 suppliers in 3 countries

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2-Methylaziridine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Propyleneimine is used as a chemical intermediate in the manufacture of a variety of paper, textile, rubber, and pharmaceutical chemicals. It is also employed in the production of latex surface-coating resins to improve adhesion.

Organic intermediate whose derivatives are used in the paper, textile, rubber, and pharmaceutical industries.

2-Methylaziridine is used in the United States exclusively as a chemical intermediate, and its derivatives are used in the paper, textile, rubber, and pharmaceutical industries. Because it easily forms imines, its primary use is in the modification of latex surface-coating resins to improve adhesion. Because of the substantive bonding of imines to cellulose derivatives, polymers modified with 2-methylaziridine or its derivatives have been used in the adhesive, textile, and paper industries.

Read more

2-Methylaziridine has been used to modify dyes for specific adhesion to cellulose, and derivatives have been used in photography, gelatins, and synthetic resins. In the oil-additive industry, 2-methylaziridine and its derivatives have been used as modifiers for viscosity control, high-pressure performance, and oxidation resistance. Other applications include use in flocculants in petroleum refining, as a modifier for rocket propellant fuels, in fiber modification, and in imine derivatives for use in medicinal and agricultural chemicals.

1,2-Propyleneimine is used as an intermediate in the paper, textile, rubber, and pharmaceutical industries. Its main use is to improve the adhesion of latex surface-coating resins.

Industrial uses: Intermediate.

Pharmacology

Propylenimine is a synthetic, flammable, volatile, colorless oily liquid that is soluble in water, ethanol and most organic solvents. Propylenimine is used in the United States exclusively as an intermediate, and its derivatives are used in the paper, textile, rubber and pharmaceutical industries. Due to its volatility, potential exposure could occur during production, packaging, or use of substances made with this liquid. The primary routes of potential human exposure to propylenimine are inhalation, ingestion and dermal contact. It is reasonably anticipated to be a human carcinogen. (NCI05)

How it is made

2-Methylaziridine can be prepared by addition of hydrogen chloride to 1-amino-2-propanol to form 2-chloropropylamine hydrochloride which is then treated with sodium hydroxide. It is manufactured commercially by combining 1,2-dichloropropane with ammonia at elevated temperatures.

Regulatory status

Inventories, regulations and trade controls that list this substance

Europe

  • EU harmonised classification (CLP Annex VI)
    Index no: 613-033-00-6

Health and food

  • EU Cosmetics Regulation Annex II, prohibited in cosmetics
    Name: 2-Methylaziridine (propyleneimine), Ref no: 730, Annex ref: II/730

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code 2-Methylaziridine is traded under.

HS 2933.99Indicative HS code

Heterocyclic compounds with nitrogen hetero-atom(s) only, other

World exports in 2024
$12.1B
−31.0% vs 2023, imports $28.8B
2019 to 2024
Top exporters
  1. China30.5%
  2. India * partner reported16.3%
  3. Ireland9.0%
Top importers
  1. Slovenia31.7%
  2. Italy24.2%
  3. United States5.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for 2-Methylaziridine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about 2-Methylaziridine, based on the data on this page

What is 2-Methylaziridine?

2-Methylaziridine is a member of aziridines.

What is the CAS number of 2-Methylaziridine?

The CAS registry number of 2-Methylaziridine is 75-55-8.

What is the molecular formula and weight of 2-Methylaziridine?

The molecular formula of 2-Methylaziridine is C3H7N and its molar mass is 57.10 g/mol.

What is 2-Methylaziridine used for?

Propyleneimine is used as a chemical intermediate in the manufacture of a variety of paper, textile, rubber, and pharmaceutical chemicals. It is also employed in the production of latex surface-coating resins to improve adhesion.

Is 2-Methylaziridine hazardous?

2-Methylaziridine carries the GHS signal word "Danger". Main hazards: highly flammable liquid and vapour, fatal if swallowed, fatal in contact with skin. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of 2-Methylaziridine?

2-Methylaziridine is usually classified under HS code 293399 (Heterocyclic compounds with nitrogen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy 2-Methylaziridine?

CompoundList lists 6 suppliers of 2-Methylaziridine in United States, China and Japan. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of 2-Methylaziridine?

Suppliers quote 2-Methylaziridine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle 2-Methylaziridine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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