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3-Hydroxypropionic acid

Also known as 3-Hydroxypropanoic acid, Hydracrylic acid, beta-Hydroxypropionic acid

3-Hydroxypropionic acid chemical structure, C3H6O3, CAS 503-66-2
2D chemical structure

Key facts

What buyers check first

CAS number
503-66-2
Formula
C3H6O3
Molar mass
90.08 g/mol
EC number
207-974-8
HS code
291819
Category
Impurities and reference standards

What is 3-Hydroxypropionic acid?

Plain description, key identifiers and synonyms

3-hydroxypropionic acid is a 3-hydroxy monocarboxylic acid that is propionic acid in which one of the hydrogens attached to the terminal carbon is replaced by a hydroxy group. It has a role as an Escherichia coli metabolite and a human metabolite. It is an omega-hydroxy-short-chain fatty acid and a 3-hydroxy monocarboxylic acid. It is functionally related to a propionic acid. It is a conjugate acid of a 3-hydroxypropionate.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-hydroxypropanoic acid
CAS number
503-66-2 CAS number cross-checkedOther or deprecated CAS: 25718-95-0
EC number
207-974-8
Molecular formula
C3H6O3
UNII
C4ZF6XLD2X
MDL number
MFCD00058998
INCI name
3-HYDROXYPROPIONIC ACID
InChIKey
ALRHLSYJTWAHJZ-UHFFFAOYSA-N
InChI
InChI=1S/C3H6O3/c4-2-1-3(5)6/h4H,1-2H2,(H,5,6)
SMILES (canonical and isomeric)
C(CO)C(=O)O

Synonyms

  • 3-Hydroxypropanoic acid
  • Hydracrylic acid
  • beta-Hydroxypropionic acid
  • hydroxypropionic acid
  • Ethylene lactic acid
  • beta-Lactic acid
  • 3-Hydroxypropanoate
  • beta-hydroxypropionate
  • Propanoic acid, 3-hydroxy-
  • 3-Hydroxy-propanoic acid
  • Ethylenelacticacid
  • Glyceric acid, 2-deoxy-
  • b-Hydroxypropionate
  • Propionic acid, 3-hydroxy-
  • 3-Hydroxypropionic Acid (contains varying amounts of 3,3-Oxydipropionic Acid)
  • b-Hydroxypropionic acid
  • 3-Hydroxypropionic acid, 30% in water
  • 3-Hydroxypropanoic acid30% in water
  • Ethylenelactic acid
  • Famotidine Impurity 13
  • beta-Hydroxypropionicacid
  • Ethylenelactate
  • beta-lacticacid
  • b-Lactic acid
  • 2-Deoxyglycerate
Show all 31 synonyms
  • 2-Deoxy-glycericaci
  • 2-Deoxyglyceric acid
  • Glycericacid,2-deoxy-
  • Propionicacid,3-hydroxy-
  • beta-Hydroxypropionsalphaure
  • Alrhlsyjtwahjz-uhfffaoysa-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
90.08 g/molcalc.
Exact mass
90.0317 Dacalc.
LogP (octanol/water)
-0.55calc.
Topological polar surface area
57.53 ร…ยฒcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
2calc.
Heavy atoms
6calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.67calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS05: Corrosive
Corrosive
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H315Causes skin irritation.
  • H318Causes serious eye damage.
  • H335May cause respiratory irritation.
Precautionary statements (19)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

3-Hydroxypropionic acid suppliers

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3-Hydroxypropionic acid price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name 3-HYDROXYPROPIONIC ACID(skin conditioning - miscellaneous)

Roles

  • Escherichia coli metabolite
  • animal metabolite
  • bacterial metabolite
  • eukaryotic metabolite
  • human metabolite
  • mammalian metabolite
  • metabolite
  • prokaryotic metabolite

Cosmetic functions

  • Skin conditioning - miscellaneous

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code 3-Hydroxypropionic acid is traded under.

HS 2918.19Indicative HS code

Carboxylic acids with alcohol function but without other oxygen function, theirโ€ฆ

World exports in 2024
$1.37B
+0.5% vs 2023, imports $1.18B
2019 to 2024
Top exporters
  1. China23.7%
  2. Italy14.7%
  3. India * partner reported12.0%
Top importers
  1. Germany11.7%
  2. South Korea9.8%
  3. Italy9.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for 3-Hydroxypropionic acid is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about 3-Hydroxypropionic acid, based on the data on this page

What is 3-Hydroxypropionic acid?

3-hydroxypropionic acid is a 3-hydroxy monocarboxylic acid that is propionic acid in which one of the hydrogens attached to the terminal carbon is replaced by a hydroxy group. It has a role as an Escherichia coli metabolite and a human metabolite.

What is the CAS number of 3-Hydroxypropionic acid?

The CAS registry number of 3-Hydroxypropionic acid is 503-66-2. Other or deprecated CAS numbers: 25718-95-0.

What is the molecular formula and weight of 3-Hydroxypropionic acid?

The molecular formula of 3-Hydroxypropionic acid is C3H6O3 and its molar mass is 90.08 g/mol.

What is 3-Hydroxypropionic acid used for?

Known uses and roles of 3-Hydroxypropionic acid include skin conditioning agents in cosmetics and personal care, escherichia coli metabolite, animal metabolite, bacterial metabolite, eukaryotic metabolite and 5 more.

Is 3-Hydroxypropionic acid hazardous?

3-Hydroxypropionic acid carries the GHS signal word "Danger". Main hazards: harmful if swallowed, causes skin irritation, causes serious eye damage. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of 3-Hydroxypropionic acid?

3-Hydroxypropionic acid is usually classified under HS code 291819 (Carboxylic acids with alcohol function but without other oxygen function, theirโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy 3-Hydroxypropionic acid?

CompoundList lists 44 suppliers of 3-Hydroxypropionic acid in China, United States, Germany, United Kingdom and 5 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of 3-Hydroxypropionic acid?

Suppliers quote 3-Hydroxypropionic acid on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle 3-Hydroxypropionic acid

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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