Acrylamide
Also known as 2-Propenamide, prop-2-enamide, Propenamide
Key facts
What buyers check first

What is Acrylamide?
Plain description, key identifiers and synonyms
Acrylamide is a member of the class of acrylamides that results from the formal condensation of acrylic acid with ammonia. It has a role as an alkylating agent, a mutagen, a carcinogenic agent, a neurotoxin and a Maillard reaction product. It is a primary carboxamide, a member of acrylamides and a N-acylammonia. It is functionally related to an acrylic acid.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- prop-2-enamide
- CAS number
- 79-06-1 CAS number cross-checkedOther or deprecated CAS: 9082-06-8, 91079-40-2
- EC numbers
- 201-173-7, 293-428-4, 618-657-2
- Molecular formula
- C3H5NO
- UNII
- 20R035KLCI
- MDL number
- MFCD00008032, MFCD00084392
- INCI name
- POLYACRYLAMIDE
- InChIKey
- HRPVXLWXLXDGHG-UHFFFAOYSA-N
- InChI
- InChI=1S/C3H5NO/c1-2-3(4)5/h2H,1H2,(H2,4,5)
- SMILES (canonical and isomeric)
- C=CC(=O)N
Synonyms
- 2-Propenamide
- prop-2-enamide
- Propenamide
- Acrylic acid amide
- Acrylic amide
- Ethylenecarboxamide
- Vinyl amide
- Akrylamid
- Acrylagel
- Propeneamide
- Optimum
- Amresco Acryl-40
- Propenoic acid amide
- Ethylene Carboxamide
- Amid kyseliny akrylove
- RCRA waste number U007
- Acrylamide Monomer
- Acrylic acid amide (50%)
- 2-Propeneamide
- Amide propenoic acid
- Casein peptone
- acryl amide
- Flokonit E
- Acrylamide Monome
- Stipix AD
Show all 34 synonymsShow fewer synonyms
- Superfloc 84
- Sumitex A 1
- Superfloc 900
- Nacolyte 673
- Aerofloc 3453
- Acrylamide, electrophoresis grade
- AAM
- Acrylamide, ultra pure
- Acrylamide 1000 microg/mL in Methanol
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Appearance | Flake-like crystals from benzeneexp.Measured value |
|---|---|
| Odour | Odorlessexp.Measured value |
| Melting point | 84.5 °Cexp.Measured value |
| Boiling point | 192.6 °Cexp.Measured value |
| Density | 1.13 g/cm³exp.Measured value |
| Flash point | 138 °Cexp.Measured value |
| Autoignition temperature | 240 °Cexp.Measured value |
| Solubility | In water, 3.711 × 10⁺² g/L at 20 °C, 4.048 × 10⁺² g/L at 30 °Cexp.Measured value |
| Vapour pressure | 0.9 Pa (7 × 10⁻³ mm Hg) at 25 °Cexp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 71.08 g/molcalc.Computed value |
|---|---|
| Exact mass | 71.0371 Dacalc.Computed value |
| LogP (octanol/water) | -0.34calc.Computed value |
| Topological polar surface area | 43.09 Ųcalc.Computed value |
| Hydrogen bond donors | 1calc.Computed value |
| Hydrogen bond acceptors | 1calc.Computed value |
| Rotatable bonds | 1calc.Computed value |
| Heavy atoms | 5calc.Computed value |
| Rings | 0calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 0calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H301Toxic if swallowed.
- H312Harmful in contact with skin.
- H315Causes skin irritation.
- H317May cause an allergic skin reaction.
- H319Causes serious eye irritation.
- H332Harmful if inhaled.
- H340May cause genetic defects.
- H350May cause cancer.
- H361fSuspected of damaging fertility.
- H372Causes damage to organs through prolonged or repeated exposure.
Precautionary statements (24)
- P203Obtain, read and follow all safety instructions before use.
- P260Do not breathe dust, fume, gas, mist, vapours or spray.
- P261Avoid breathing dust, fume, gas, mist, vapours or spray.
- P264Wash skin thoroughly after handling.
- P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
- P270Do not eat, drink or smoke when using this product.
- P271Use only outdoors or in a well-ventilated area.
- P272Contaminated work clothing should not be allowed out of the workplace.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P301 + P316If swallowed: Get emergency medical help immediately.
- P302 + P352If on skin: Wash with plenty of water.
- P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
- P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P317Get medical help.
- P318If exposed or concerned, get medical advice.
- P319Get medical help if you feel unwell.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P330Rinse mouth.
- P332 + P317If skin irritation occurs: Get medical help.
- P333 + P317If skin irritation or rash occurs: Get medical help.
- P337 + P317If eye irritation persists: Get medical help.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
- UN number
- UN 2074
- Transport hazard class
- 6.1
- Packing group
- III
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidAcrylamide suppliers
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- India, AhmedabadUnclaimed profileAcrylamideGrade, purity and minimum order on requestPrice on request
- China, ChangshuUnclaimed profileAcrylamideGrade, purity and minimum order on requestPrice on request
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Where suppliers are based
225 suppliers in 31 countries
- India57
- China48
- United States48
- United Kingdom8
- Turkey7
- Germany6
- and 25 more countries
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Acrylamide price
Indicative price range per kg from live supplier offers
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Uses and applications
What the substance is used for, by industry and function
It is used as a reactive monomer and intermediate in the production of organic chemicals. Acrylamide has a wide variety of uses as a polymer or copolymer in such applications as adhesives, fibers, paper sizing, molded parts, water coagulant aids, grouting agent, and textiles.
Synthesis of dyes, ... cross-linking agent, adhesives, paper and textile sizes, soil-conditioning agents, flocculants, sewage and waste treatment, ore processing, permanent-press fabrics.
Used in electrophoresis, molecular biology, genetic engineering.
Acrylamide is used as a reactive monomer and intermediate in the production of organic chemicals and in the synthesis of polyacrylamides. Acrylamide is also used as a flocculent for sewage and waste treatment, soil conditioning agents, ore processing, paper and textile industries, and in the manufacture of dyes, adhesives, and permanent press fabrics.
Industrial uses: Monomers, Processing aids, specific to petroleum production.
Industries and functions
Cosmetic ingredient, INCI name POLYACRYLAMIDE(antistatic, binding, film forming)
Roles
- Maillard reaction product
- aetiopathogenetic role
- alkylating agent
- carcinogenic agent
- genotoxin
- mutagen
- neurotoxin
- poison
- thermal degradation product
Functional uses
- Anti-slip agent
- Anti-static agent
- Binder
- Emulsifier
- Film former
- Hair fixative
- Thickening agent
Cosmetic functions
- Antistatic
- Binding
- Film forming
Pharmacology
Acrylamide is a colorless, odorless, crystalline amide that polymerizes rapidly and can form as a byproduct during the heating of starch-rich foods to high temperatures. Acrylamide is used in the production of polymers mainly in the water treatment industry, pulp and paper industry and textile treatment industry and is used as a laboratory reagent. The polymer is nontoxic, but exposure to the monomer can cause central and peripheral nervous system damage resulting in hallucinations, drowsiness and numbness in the hands and legs. Acrylamide is reasonably anticipated to be a human carcinogen. (NCI05)
How it is made
Sulfuric Acid Process. One mole of acrylonitrile is added to a solution of 1 mol sulfuric acid and 1 mol of water at 60 °C. The mixture is slowly heated to 80 °C, kept for an hour at this temperature, and then cooled to 40 °C. Ammonium sulfate precipitates on neutralization with ammonia and is filtered out. The acrylamide, which crystallizes on cooling the mother liquor to below 10 °C, is purified by recrystallization from benzene.
Catalytic Hydration Process. ... A 50 wt% solution of acrylonitrile in water is slurried with a catalyst such as Raney copper and kept at 120 °C for 2.5 hr.
Read more
Conversion of acrylonitrile is greater than 50% and selectivity to the amide is nearly 100%. This process conveniently makes an aqueous solution of 30 to 50 wt% acrylamide because of the large amount of water required in the reaction.
Prepared from acrylonitrile by treatment with H2SO4 or HCl.
Regulatory status
Inventories, regulations and trade controls that list this substance
Europe
- EU harmonised classification (CLP Annex VI)Index no: 616-003-00-0
Health and food
- EU cosmetic ingredient inventory
- EU Cosmetics Regulation Annex II, prohibited in cosmeticsName: Acrylamide, unless regulated elsewhere in this Regulation, Ref no: 681, Annex ref: II/681
United States
- TSCA inventory (USA)Status: Active in US commerce
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Acrylamide is traded under.
Acyclic amides (including acyclic carbamates) and their derivatives, salts thereof, other
- United States17.5%
- Germany8.8%
- India * partner reported6.7%
* Partner reported figures, a lower bound.
The HS code shown for Acrylamide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Acrylamide, based on the data on this page
What is Acrylamide?
What is the CAS number of Acrylamide?
What is the molecular formula and weight of Acrylamide?
What is Acrylamide used for?
Is Acrylamide hazardous?
What is the HS code of Acrylamide?
Where can I buy Acrylamide?
Where can I buy Acrylamide in India?
What is the price of Acrylamide?
Guides for buyers
Practical guides that help when you source, ship or handle Acrylamide
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, Trade and logisticsShipping dangerous goods: UN numbers, classes and packing groupsHow the UN dangerous goods system works for chemicals, from the nine classes and UN numbers to packing groups, UN packaging marks, labels, documents and segregation.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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