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Impurities and reference standards

(-)-Anatabine

Also known as Anatabine, 3-[(2S)-1,2,3,6-tetrahydropyridin-2-yl]pyridine, (S)-1,2,3,6-Tetrahydro-2,3'-bipyridine

CAS 581-49-7Formula C10H12N2Molar mass 160.22 g/mol
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(-)-Anatabine chemical structure, C10H12N2, CAS 581-49-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
581-49-7
Formula
C10H12N2
Molar mass
160.22 g/mol
HS code
293979
Category
Impurities and reference standards

What is (-)-Anatabine?

Plain description, key identifiers and synonyms

Anatabine is a member of bipyridines.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-[(2S)-1,2,3,6-tetrahydropyridin-2-yl]pyridine
CAS number
581-49-7 CAS number cross-checked
Molecular formula
C10H12N2
UNII
5PP654XB7D
MDL number
MFCD01669938
InChIKey
SOPPBXUYQGUQHE-JTQLQIEISA-N
InChI
InChI=1S/C10H12N2/c1-2-7-12-10(5-1)9-4-3-6-11-8-9/h1-4,6,8,10,12H,5,7H2/t10-/m0/s1
Canonical SMILES
C1=CCC(c2cccnc2)NC1
Isomeric SMILES
C1C=CCN[C@@H]1C2=CN=CC=C2

Synonyms

  • Anatabine
  • 3-[(2S)-1,2,3,6-tetrahydropyridin-2-yl]pyridine
  • (S)-1,2,3,6-Tetrahydro-2,3'-bipyridine
  • 2,3'-Bipyridine, 1,2,3,6-tetrahydro-, (S)-
  • 3-((2S)-1,2,3,6-tetrahydropyridin-2-yl)pyridine
  • (S)-(-)-Anatabine
  • Nicotine EP Impurity A
  • 2,3'-Bipyridine, 1,2,3,6-tetrahydro-, (2S)-
  • (2S)-1,2,3,6-tetrahydro-2,3'-bipyridine
  • (S)-Anatabine
  • Anatabine, (-)-
  • US8609708, 50 Anatabine
  • Nicotine impurity a
  • Nicotine resinate impurity a
  • Nicotine ditartrate dihydrate impurity a

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
160.22 g/molcalc.
Exact mass
160.10 Dacalc.
LogP (octanol/water)
1.67calc.
Topological polar surface area
24.92 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
1calc.
Heavy atoms
12calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.3calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1=CCC(c2cccnc2)NC1

C1=CCC(c2cccnc2)NC1

2 rings, 12 atoms, the (±)-1,2,3,6-Tetrahydro-2,3'-bipyridine ring system.

19 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

(-)-Anatabine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 5 suppliers
5 of 5 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

5 suppliers in 3 countries

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(-)-Anatabine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacology

Anatabine is an alkaloid found in low concentrations in plants in the Solanaceae family, which includes tobacco and tomato plants, with potential nicotine mimetic and anti-inflammatory activities. Following oral administration, anatabine may mimic the neurological effects of nicotine exposure. This agent may not have the addictive properties of nicotine, therefore, it may be appropriate for use in treating nicotine withdrawal symptoms during smoking cessation.

Read more

Anatabine may also exert its anti-inflammatory effect by the inhibition of the signal transducer and activator of transcription 3 (STAT3) which then prevents the activation of the nuclear factor kappa B (NF-kB), which is a key regulator of proinflammatory cytokine release. Urine concentrations of anatabine can be used to assess the extent of tobacco use.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code (-)-Anatabine is traded under.

HS 2939.79Indicative HS code

Alkaloids of vegetal origin, other than cocaine, ecgonine, salts, esters and other derivatives, not elsewhere…

World exports in 2024
$701M
+18.9% vs 2023, imports $830M
2019 to 2024
Top exporters
  1. Switzerland * partner reported25.3%
  2. Germany21.4%
  3. India * partner reported14.9%
Top importers
  1. United States20.9%
  2. Germany14.7%
  3. Italy14.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for (-)-Anatabine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about (-)-Anatabine, based on the data on this page

What is (-)-Anatabine?

Anatabine is a member of bipyridines.

What is the CAS number of (-)-Anatabine?

The CAS registry number of (-)-Anatabine is 581-49-7.

What is the molecular formula and weight of (-)-Anatabine?

The molecular formula of (-)-Anatabine is C10H12N2 and its molar mass is 160.22 g/mol.

Is (-)-Anatabine hazardous?

No GHS hazard classification for (-)-Anatabine is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of (-)-Anatabine?

(-)-Anatabine is usually classified under HS code 293979 (Alkaloids, natural or reproduced by synthesis, and their salts, ethers, esters and other…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy (-)-Anatabine?

CompoundList lists 5 suppliers of (-)-Anatabine in China, India and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy (-)-Anatabine in India?

1 supplier in India list (-)-Anatabine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of (-)-Anatabine?

Suppliers quote (-)-Anatabine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle (-)-Anatabine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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