Bezafibrate
Also known as Bezalip, Bezafibrato, Bezatol SR
Key facts
What buyers check first
- CAS number
- 41859-67-0
- Formula
- C19H20ClNO4
- Molar mass
- 361.83 g/mol
- EC number
- 255-567-9
- HS code
- 292429
- Category
- Cardiovascular and metabolic drugs
What is Bezafibrate?
Plain description, key identifiers and synonyms
Bezafibrate is a monocarboxylic acid amide obtained by the formal condensation of the carboxy group of 4-chlorobenzoic acid with the amino group of 2-[4-(2-aminoethyl)phenoxy]-2-methylpropanoic acid. Benafibrate is used for the treatment of hyperlipidaemia. It has a role as a geroprotector, an antilipemic drug, a xenobiotic and an environmental contaminant. It is a monocarboxylic acid, a monocarboxylic acid amide, an aromatic ether and a member of monochlorobenzenes. It is functionally related to a propionic acid.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methylpropanoic acid
- CAS number
- 41859-67-0 CAS number cross-checked
- EC numbers
- 255-567-9, 941-659-2
- Molecular formula
- C19H20ClNO4
- UNII
- Y9449Q51XH
- MDL number
- MFCD00078970
- InChIKey
- IIBYAHWJQTYFKB-UHFFFAOYSA-N
- InChI
- InChI=1S/C19H20ClNO4/c1-19(2,18(23)24)25-16-9-3-13(4-10-16)11-12-21-17(22)14-5-7-15(20)8-6-14/h3-10H,11-12H2,1-2H3,(H,21,22)(H,23,24)
- SMILES (canonical and isomeric)
- CC(C)(C(=O)O)OC1=CC=C(C=C1)CCNC(=O)C2=CC=C(C=C2)Cl
Synonyms
- Bezalip
- Bezafibrato
- Bezatol SR
- Bezafibratum
- BM 15.075
- Propanoic acid, 2-(4-(2-((4-chlorobenzoyl)amino)ethyl)phenoxy)-2-methyl-
- Propanoic acid, 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl-
- Beza Lande
- Beza Puren
- Bezalip-mono
- Fibrazate xl
- Zimbacol xl
- Bezagen xl
- Liparol xl
- Cedur
- Befizal
- Difaterol
- Bezafibrat
- Sklerofibrat
- Azufibrat
- Bezamerck
- Regadrin B
- Bezalip Retard
- 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methylpropanoic acid
- Bezatol SR (TN)
Show all 35 synonymsShow fewer synonyms
- 2-(4-(2-(4-Chlorobenzamido)ethyl)phenoxy)-2-methylpropanoic acid
- 2-(p-(2-(p-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acid
- Bezatol
- 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl-propanoic acid
- 2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]-2-methylpropanoic acid
- durabezur
- Reducterol
- Bezabeta
- Bezacur
- Eulitop
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 361.83 g/molcalc.Computed value |
|---|---|
| Exact mass | 361.1081 Dacalc.Computed value |
| LogP (octanol/water) | 3.55calc.Computed value |
| Topological polar surface area | 75.63 Ųcalc.Computed value |
| Hydrogen bond donors | 2calc.Computed value |
| Hydrogen bond acceptors | 3calc.Computed value |
| Rotatable bonds | 7calc.Computed value |
| Heavy atoms | 25calc.Computed value |
| Rings | 2calc.Computed value |
| Aromatic rings | 2calc.Computed value |
| Fraction sp3 carbons | 0.26calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
O=C(NCCc1ccccc1)c1ccccc1
2 rings, 17 atoms, the N-Phenethylbenzamide ring system.
1,065 other chemicals share this scaffoldSafety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H302Harmful if swallowed.
- H361Suspected of damaging fertility or the unborn child.
Precautionary statements (9)
- P203Obtain, read and follow all safety instructions before use.
- P264Wash skin thoroughly after handling.
- P270Do not eat, drink or smoke when using this product.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P301 + P317If swallowed: Get medical help.
- P318If exposed or concerned, get medical advice.
- P330Rinse mouth.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidBezafibrate suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- China, HangzhouUnclaimed profileBezafibrateGrade, purity and minimum order on requestPrice on request
- India ManufacturerUnclaimed profileBezafibrateGrade, purity and minimum order on requestPrice on request
- Italy ManufacturerUnclaimed profileBezafibrateGrade, purity and minimum order on requestPrice on request
- China, ChangzhouUnclaimed profileBezafibrateGrade, purity and minimum order on requestPrice on request
- China, SuzhouUnclaimed profileBezafibrateGrade, purity and minimum order on requestPrice on request
- Italy, SegrateUnclaimed profileBezafibrateGrade, purity and minimum order on requestPrice on request
- China, ChangzhouUnclaimed profileBezafibrateGrade, purity and minimum order on requestPrice on request
- India, AhmedabadUnclaimed profileBezafibrateGrade, purity and minimum order on requestPrice on request
- Italy, Rodano ManufacturerUnclaimed profileBezafibrateGrade, purity and minimum order on requestPrice on request
- Japan, Ampachi-Gun ManufacturerUnclaimed profileBezafibrateGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
111 suppliers in 17 countries
- United States39
- China36
- India6
- Germany5
- United Kingdom5
- Spain3
- and 11 more countries
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Bezafibrate price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Use classes: Cardiovascular system.
Industries and functions
Pharmacological actions
- Hypolipidemic Agents
Roles
- anticholesteremic drug
- antilipemic drug
- antineoplastic agent
- antipsychotic agent
- cardiovascular drug
- central nervous system depressant
- central nervous system drug
- environmental contaminant
- geroprotector
- hypoglycemic agent
- pharmaceutical
- protective agent
- psychotropic drug
- tranquilizing drug
- xenobiotic
Functional uses
- Pharmaceutical
Pharmacology
Bezafibrate is an agonist of peroxisome proliferator-activated receptor alpha (PPARalpha) with antilipidemic activity. Bezafibrate decreases triglyceride levels, increases high density lipoprotein (HDL) cholesterol levels, and decreases total and low density lipoprotein (LDL) cholesterol levels.
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- Active ingredient in FDA approved drug labels
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Bezafibrate is traded under.
Cyclic amides (including cyclic carbamates) and their derivatives, salts thereof, other
- China32.3%
- Switzerland * partner reported13.6%
- Norway * partner reported12.8%
- United States15.9%
- Ireland15.8%
- Germany11.9%
* Partner reported figures, a lower bound.
The HS code shown for Bezafibrate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Bezafibrate, based on the data on this page
What is Bezafibrate?
What is the CAS number of Bezafibrate?
What is the molecular formula and weight of Bezafibrate?
What is Bezafibrate used for?
Is Bezafibrate hazardous?
What is the HS code of Bezafibrate?
Where can I buy Bezafibrate?
Where can I buy Bezafibrate in India?
What is the price of Bezafibrate?
Guides for buyers
Practical guides that help when you source, ship or handle Bezafibrate
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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