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Sulfur and phosphorus compounds

Bisphenol S

Also known as 4,4'-Sulfonyldiphenol, Bis(4-hydroxyphenyl) sulfone, Phenol, 4,4'-sulfonylbis-

CAS 80-09-1Formula C12H10O4SMolar mass 250.28 g/molEC 201-250-5
GHS signal word: Danger. Pictograms: Serious health hazard 85 suppliers listed
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Bisphenol S chemical structure, C12H10O4S, CAS 80-09-1
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
White, crystalline powder
Melting point
240.5 °C
Density
1.3663 g/cm³ at 15 °C
Solubility
Insoluble in water
HS code
293090
Category
Sulfur and phosphorus compounds
Illustrative photo, off-white crystalline powder in fibre drums in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Bisphenol S?

Plain description, key identifiers and synonyms

4,4'-sulfonyldiphenol is a sulfone that is diphenyl sulfone in which both of the para hydrogens have been replaced by hydroxy groups. It has a role as an endocrine disruptor and a metabolite. It is a bisphenol and a sulfone. It is functionally related to a diphenyl sulfone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-(4-hydroxyphenyl)sulfonylphenol
CAS number
80-09-1 CAS number cross-checkedOther or deprecated CAS: 25641-61-6
EC numbers
201-250-5, 247-158-9
Molecular formula
C12H10O4S
UNII
3OX4RR782R
MDL number
MFCD00002350
InChIKey
VPWNQTHUCYMVMZ-UHFFFAOYSA-N
InChI
InChI=1S/C12H10O4S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8,13-14H
SMILES (canonical and isomeric)
C1=CC(=CC=C1O)S(=O)(=O)C2=CC=C(C=C2)O

Synonyms

  • 4,4'-Sulfonyldiphenol
  • Bis(4-hydroxyphenyl) sulfone
  • Phenol, 4,4'-sulfonylbis-
  • 4-(4-hydroxyphenyl)sulfonylphenol
  • 4,4'-Dihydroxydiphenyl sulfone
  • Bis(p-hydroxyphenyl) sulfone
  • Diphone C
  • Bis(4-hydroxyphenyl)sulfone
  • 1,1'-Sulfonylbis(4-hydroxybenzene)
  • BPS 1
  • 4,4'-Sulphonyldiphenol
  • 1,1'-Sulfonylbis[4-hydroxybenzene]
  • 4,4-Sulfonyldiphenol
  • 4,4'-Sulfonylbisphenol
  • 4-Hydroxyphenyl sulfone
  • 4,4'-Bisphenol S
  • Sulphonylbisphenol
  • Bis(p-hydroxyphenyl)sulfone
  • P,P'-Dihydroxydiphenyl sulfone
  • Phenol, 4,4'-sulfonyldi-
  • 4-[(4-hydroxyphenyl)sulfonyl]phenol
  • 4,4'-dihydroxy diphenyl sulfone
  • Bisphenol-s
  • 4-(4-hydroxybenzenesulfonyl)phenol
  • bisphenols
Show all 37 synonyms
  • 4,4'-dihydroxydiphenylsulfone
  • 4,4'-Dihydroxydiphenyl sulphone
  • 4-(4-hydroxyphenylsulfonyl)phenol
  • DHDPhS
  • Phenol,4'-sulfonylbis-
  • 4,4\'-sulfonyldiphenol
  • Bisphenol S (4,4')
  • 4,4'-Sulfonylbis[phenol]
  • Cambridge id 5137133
  • di-(4-Hydroxyphenyl)sulfone
  • 4-06-00-05809 (Beilstein Handbook Reference)
  • bis(4-hydroxylphenyl) sulfone

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
White, crystalline powderexp.
Melting point
240.5 °Cexp.
Density
1.3663 g/cm³ at 15 °Cexp.
Solubility
Insoluble in waterexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
250.28 g/molcalc.
Exact mass
250.03 Dacalc.
LogP (octanol/water)
1.93calc.
Topological polar surface area
74.6 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
2calc.
Heavy atoms
17calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=S(=O)(c1ccccc1)c1ccccc1

O=S(=O)(c1ccccc1)c1ccccc1

2 rings, 15 atoms, the Diphenyl sulfone ring system.

1,066 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H360FDMay damage fertility. May damage the unborn child.
Precautionary statements (5)
  • P203Obtain, read and follow all safety instructions before use.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Bisphenol S suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 85 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

85 suppliers in 13 countries

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Bisphenol S price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Intermediate, product modification.

Has been patented for a variety of applications, eg, as an electroplating solvent, a washfastening agent, and a component in a phenolic resin.

Bisphenol S is used as a developer in thermal paper, including in products marketed as "BPA-free paper".

Industrial uses: Etching agent, Surfactant (surface active agent), Monomers, Other, Polymerization promoter.

Consumer uses: Etching agent, Monomers, Other.

Roles

  • endocrine disruptor
  • hormone receptor modulator
  • metabolite
  • pharmaceutical
  • receptor modulator

Regulatory status

Inventories, regulations and trade controls that list this substance

Europe

  • EU harmonised classification (CLP Annex VI)
    Index no: 604-098-00-1

Health and food

  • EU Cosmetics Regulation Annex II, prohibited in cosmetics
    Name: 4,4’-sulphonyldiphenol, bisphenol S, Ref no: 1702, Annex ref: II/1702

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Bisphenol S is traded under.

HS 2930.90Indicative HS code

Organo-sulphur compounds, other

World exports in 2024
$5.83B
+0.1% vs 2023, imports $5.93B
2019 to 2024
Top exporters
  1. China40.7%
  2. United States10.9%
  3. Japan9.3%
Top importers
  1. United States13.3%
  2. Brazil12.6%
  3. China6.6%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Bisphenol S is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Bisphenol S, based on the data on this page

What is Bisphenol S?

4,4'-sulfonyldiphenol is a sulfone that is diphenyl sulfone in which both of the para hydrogens have been replaced by hydroxy groups. It has a role as an endocrine disruptor and a metabolite. It is a bisphenol and a sulfone. It is functionally related to a diphenyl sulfone.

What is the CAS number of Bisphenol S?

The CAS registry number of Bisphenol S is 80-09-1. Other or deprecated CAS numbers: 25641-61-6.

What is the molecular formula and weight of Bisphenol S?

The molecular formula of Bisphenol S is C12H10O4S and its molar mass is 250.28 g/mol.

What is Bisphenol S used for?

Intermediate, product modification. Has been patented for a variety of applications, eg, as an electroplating solvent, a washfastening agent, and a component in a phenolic resin. Bisphenol S is used as a developer in thermal paper, including in products marketed as "BPA-free paper".

Is Bisphenol S hazardous?

Bisphenol S carries the GHS signal word "Danger". Main hazards: may damage fertility. may damage the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Bisphenol S?

Bisphenol S is usually classified under HS code 293090 (Organo-sulphur compounds, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Bisphenol S?

CompoundList lists 85 suppliers of Bisphenol S in China, United States, Canada, Germany and 9 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Bisphenol S in India?

2 suppliers in India list Bisphenol S on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Bisphenol S?

Suppliers quote Bisphenol S on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Bisphenol S

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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