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Pharmaceuticals and APIs

Brimonidine

Also known as Bromoxidine, 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine, 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline

CAS 59803-98-4Formula C11H10BrN5Molar mass 292.14 g/molEC 620-306-3
GHS signal word: Danger. Pictograms: Acute toxicity (severe) 104 suppliers listed Drug substance
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Brimonidine chemical structure, C11H10BrN5, CAS 59803-98-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
59803-98-4
Formula
C11H10BrN5
Molar mass
292.14 g/mol
EC number
620-306-3
HS code
293329
Category
Pharmaceuticals and APIs

What is Brimonidine?

Plain description, key identifiers and synonyms

Brimonidine is a member of imidazoles, a secondary amine and a quinoxaline derivative. It has a role as an alpha-adrenergic agonist, an antihypertensive agent and an adrenergic agonist.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine
CAS number
59803-98-4 CAS number cross-checked
EC number
620-306-3
Molecular formula
C11H10BrN5
UNII
E6GNX3HHTE
MDL number
MFCD00153878
InChIKey
XYLJNLCSTIOKRM-UHFFFAOYSA-N
InChI
InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)
SMILES (canonical and isomeric)
C1CN=C(N1)NC2=C(C3=NC=CN=C3C=C2)Br

Synonyms

  • Bromoxidine
  • 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine
  • 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline
  • brimonidina
  • brimonidinum
  • UK-1430418 FREE BASE
  • AGN-190342 FREE BASE
  • Brimodine
  • UK 14,304
  • 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-6-quinoxalinamine
  • 6-Quinoxalinamine, 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-
  • AGN 190342
  • C11H10BrN5
  • UK 14304
  • 5-Bromo-N-(2-imidazolin-2-yl)-6-quinoxalinamine
  • Brimonidine (INN)
  • UK 14304, AGN190342
  • UK 14304-18
  • UK 14304 (tartrate), AGN190342 (tartrate)
  • 5-Bromo-N-(4,5-dihydro-2-imidazolyl)quinoxalin-6-amine
  • LK 14304-18
  • Brimonidine (Standard)
  • Tocris-0425
  • [3H]-UK14304
  • Brimonidine 100 microg/mL in Acetonitrile
Show all 27 synonyms
  • brimonidine (UK14304)
  • [3H]brimonidine (UK14304)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
292.14 g/molcalc.
Exact mass
291.012 Dacalc.
LogP (octanol/water)
1.76calc.
Topological polar surface area
62.2 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
1calc.
Heavy atoms
17calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.18calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1cnc2cc(NC3=NCCN3)ccc2n1

c1cnc2cc(NC3=NCCN3)ccc2n1

3 rings, 16 atoms, the N-(4,5-Dihydro-1H-imidazol-2-yl)quinoxalin-6-amine ring system.

15 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)

Hazard statements

  • H301Toxic if swallowed.
Precautionary statements (7)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Brimonidine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 104 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

104 suppliers in 16 countries

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Brimonidine price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Roles

  • adrenergic agent
  • adrenergic agonist
  • alpha-adrenergic agonist
  • alpha-adrenergic drug
  • antiglaucoma drug
  • antihypertensive agent
  • cardiovascular drug
  • neurotransmitter agent
  • ophthalmology drug
  • pharmaceutical

Pharmacology

Brimonidine is an alpha-Adrenergic Agonist. The mechanism of action of brimonidine is as an Adrenergic alpha-Agonist.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Brimonidine is traded under.

HS 2933.29Indicative HS code

Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the…

World exports in 2024
$1.43B
−7.6% vs 2023, imports $1.47B
2019 to 2024
Top exporters
  1. China28.1%
  2. France * partner reported12.7%
  3. India * partner reported10.3%
Top importers
  1. United Kingdom13.0%
  2. United States7.9%
  3. China6.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Brimonidine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Brimonidine, based on the data on this page

What is Brimonidine?

Brimonidine is a member of imidazoles, a secondary amine and a quinoxaline derivative. It has a role as an alpha-adrenergic agonist, an antihypertensive agent and an adrenergic agonist.

What is the CAS number of Brimonidine?

The CAS registry number of Brimonidine is 59803-98-4.

What is the molecular formula and weight of Brimonidine?

The molecular formula of Brimonidine is C11H10BrN5 and its molar mass is 292.14 g/mol.

What is Brimonidine used for?

Use classes: Pharmaceuticals.

Is Brimonidine hazardous?

Brimonidine carries the GHS signal word "Danger". Main hazards: toxic if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Brimonidine?

Brimonidine is usually classified under HS code 293329 (Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Brimonidine?

CompoundList lists 104 suppliers of Brimonidine in United States, China, India, United Kingdom and 12 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Brimonidine in India?

9 suppliers in India list Brimonidine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Brimonidine?

Suppliers quote Brimonidine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Brimonidine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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