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Analgesics and anti-inflammatories

Bufexamac

Also known as 2-(4-Butoxyphenyl)-N-hydroxyacetamide, Bufexamic acid, Parfenac

CAS 2438-72-4Formula C12H17NO3Molar mass 223.27 g/molEC 219-451-1
GHS signal word: Warning. Pictograms: Harmful or irritant 22 suppliers listed
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Bufexamac chemical structure, C12H17NO3, CAS 2438-72-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
2438-72-4
Formula
C12H17NO3
Molar mass
223.27 g/mol
EC number
219-451-1
HS code
292800
Category
Analgesics and anti-inflammatories

What is Bufexamac?

Plain description, key identifiers and synonyms

Bufexamac is a hydroxamic acid derived from phenylacetamide in which the benzene moiety is substituted at C-4 by a butoxy group. It has anti-inflammatory, analgesic, and antipyretic properties. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic and an antipyretic. It is a hydroxamic acid and an aromatic ether.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-(4-butoxyphenyl)-N-hydroxyacetamide
CAS number
2438-72-4 CAS number cross-checked
EC number
219-451-1
Molecular formula
C12H17NO3
UNII
4T3C38J78L
MDL number
MFCD00078936
InChIKey
MXJWRABVEGLYDG-UHFFFAOYSA-N
InChI
InChI=1S/C12H17NO3/c1-2-3-8-16-11-6-4-10(5-7-11)9-12(14)13-15/h4-7,15H,2-3,8-9H2,1H3,(H,13,14)
SMILES (canonical and isomeric)
CCCCOC1=CC=C(C=C1)CC(=O)NO

Synonyms

  • 2-(4-Butoxyphenyl)-N-hydroxyacetamide
  • Bufexamic acid
  • Parfenac
  • Anderm
  • Paraderm
  • Bufexamaco
  • p-Butoxyphenylacetohydroxamic acid
  • 4-Butoxy-N-hydroxybenzeneacetamide
  • Bufexamacum
  • 4-Butoxyphenylacetohydroxamic acid
  • 2-(p-Butoxyphenyl)-acetohydroxamic acid
  • CP 1044 J3
  • Acide p-butoxyphenylacethydroxamique
  • Bufexamacratiopharm
  • Bufexamac ratiopharm
  • p-Butoxyphenylacethydroxamic Acid
  • p Butoxyphenylacethydroxamic Acid
  • Droxaryl
  • Parfenal
  • Feximac
  • Mofenar
  • Flogicid
  • Malipuran
  • Norfemac
  • Flogocid N plastigel
Show all 33 synonyms
  • 2-(p-Butoxyphenyl)acetohydroxamic acid
  • Benzeneacetamide, 4-butoxy-N-hydroxy-
  • 2-(4-butoxyphenyl)acetohydroxamic acid
  • CP 1044
  • ACETOHYDROXAMIC ACID, 2-(p-BUTOXYPHENYL)-
  • 2-(4-butoxyphenyl)ethanehydroxamic acid
  • Droxarol
  • Bufessamac

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
223.27 g/molcalc.
Exact mass
223.1208 Dacalc.
LogP (octanol/water)
1.91calc.
Topological polar surface area
58.56 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
6calc.
Heavy atoms
16calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.42calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H317May cause an allergic skin reaction.
Precautionary statements (12)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Bufexamac suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 22 suppliers
22 of 22 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

22 suppliers in 8 countries

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Bufexamac price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Anti-Inflammatory Agents, Non-Steroidal

Roles

  • analgesic
  • anti-inflammatory agent
  • anti-inflammatory drug
  • antipyretic
  • antirheumatic drug
  • non-narcotic analgesic
  • non-steroidal anti-inflammatory drug
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Bufexamac is traded under.

HS 2928.00Indicative HS code

Organic derivatives of hydrazine or of hydroxylamine

World exports in 2024
$1.38B
−9.0% vs 2023, imports $1.52B
2019 to 2024
Top exporters
  1. Switzerland * partner reported44.0%
  2. China18.4%
  3. Italy9.4%
Top importers
  1. Brazil21.8%
  2. United States12.8%
  3. Italy10.8%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Bufexamac is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Bufexamac, based on the data on this page

What is Bufexamac?

Bufexamac is a hydroxamic acid derived from phenylacetamide in which the benzene moiety is substituted at C-4 by a butoxy group. It has anti-inflammatory, analgesic, and antipyretic properties. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic and an antipyretic.

What is the CAS number of Bufexamac?

The CAS registry number of Bufexamac is 2438-72-4.

What is the molecular formula and weight of Bufexamac?

The molecular formula of Bufexamac is C12H17NO3 and its molar mass is 223.27 g/mol.

What is Bufexamac used for?

Use classes: Pharmaceuticals.

Is Bufexamac hazardous?

Bufexamac carries the GHS signal word "Warning". Main hazards: harmful if swallowed, may cause an allergic skin reaction. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Bufexamac?

Bufexamac is usually classified under HS code 292800 (Organic derivatives of hydrazine or of hydroxylamine). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Bufexamac?

CompoundList lists 22 suppliers of Bufexamac in China, United States, Italy, Germany and 4 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Bufexamac in India?

1 supplier in India list Bufexamac on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Bufexamac?

Suppliers quote Bufexamac on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Bufexamac

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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