Cefovecin
Also known as Cefovecin (ema epar: veterinary), cefovecina, cefovecine
Key facts
What buyers check first
- CAS number
- 234096-34-5
- Formula
- C17H19N5O6S2
- Molar mass
- 453.50 g/mol
- HS code
- 294190
- Category
- Impurities and reference standards
What is Cefovecin?
Plain description, key identifiers and synonyms
Cefovecin is a semisynthetic, broad-spectrum, third-generation cephalosporin with antibacterial activity. Cefovecin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-3-[(2S)-oxolan-2-yl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- CAS number
- 234096-34-5 CAS number cross-checked
- Molecular formula
- C17H19N5O6S2
- UNII
- 0D1OL46ZIE
- InChIKey
- ZJGQFXVQDVCVOK-QFKLAVHZSA-N
- InChI
- InChI=1S/C17H19N5O6S2/c1-27-21-10(8-6-30-17(18)19-8)13(23)20-11-14(24)22-12(16(25)26)7(5-29-15(11)22)9-3-2-4-28-9/h6,9,11,15H,2-5H2,1H3,(H2,18,19)(H,20,23)(H,25,26)/b21-10-/t9-,11+,15+/m0/s1
- Canonical SMILES
- CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(C3CCCO3)CSC12)c1csc(N)n1
- Isomeric SMILES
- CO/N=C(/C1=CSC(=N1)N)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)[C@@H]4CCCO4)C(=O)O
Synonyms
- Cefovecin (ema epar: veterinary)
- cefovecina
- cefovecine
- cefovecinum
- (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-3-[(2S)-oxolan-2-yl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- Convenia (veterinary)
- Cephalosporin Impurity 10 (Cefovecin)
- Cephalosporin Impurity 11 (Cefovecin)
- (6R,7R)-7-(((2Z)-(2-Aminothiazol-4-yl)(methoxyimino)acetyl)amino)-8-oxo-3-((2S)-tetrahydrofuran-2-yl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
- (6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-3-((S)-tetrahydrofuran-2-yl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 453.50 g/molcalc.Computed value |
|---|---|
| Exact mass | 453.0777 Dacalc.Computed value |
| LogP (octanol/water) | -0.01calc.Computed value |
| Topological polar surface area | 156.4 Ųcalc.Computed value |
| Hydrogen bond donors | 3calc.Computed value |
| Hydrogen bond acceptors | 10calc.Computed value |
| Rotatable bonds | 6calc.Computed value |
| Heavy atoms | 30calc.Computed value |
| Rings | 4calc.Computed value |
| Aromatic rings | 1calc.Computed value |
| Fraction sp3 carbons | 0.47calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 3calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Cefovecin suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- India, Chennai ManufacturerUnclaimed profileCefovecinGrade, purity and minimum order on requestPrice on request
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Where suppliers are based
1 supplier in 1 country
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Cefovecin price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Industries and functions
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- Active ingredient in FDA approved drug labels
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Cefovecin is traded under.
Antibiotics, other
- China39.7%
- United States11.3%
- Switzerland * partner reported10.9%
* Partner reported figures, a lower bound.
The HS code shown for Cefovecin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Cefovecin, based on the data on this page
What is Cefovecin?
What is the CAS number of Cefovecin?
What is the molecular formula and weight of Cefovecin?
What is Cefovecin used for?
Is Cefovecin hazardous?
What is the HS code of Cefovecin?
Where can I buy Cefovecin?
Where can I buy Cefovecin in India?
What is the price of Cefovecin?
Guides for buyers
Practical guides that help when you source, ship or handle Cefovecin
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
- Guide, Trade and logisticsHS codes for chemicals and why they matterHow the Harmonized System classifies chemicals, the chapters that matter, the rules for chemically defined compounds and mixtures, and practical steps to find the right code.Read
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