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Antibiotics and anti-infectives

Cephaloridine

Also known as cefaloridine, Cefaloridin, Cephaloridin

CAS 50-59-9Formula C19H17N3O4S2Molar mass 415.50 g/molEC 200-052-6
GHS signal word: Warning. Pictograms: Harmful or irritant 14 suppliers listed
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Cephaloridine chemical structure, C19H17N3O4S2, CAS 50-59-9
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Crystals
Flash point
No data
Solubility
SOL IN WATER
HS code
294190
Category
Antibiotics and anti-infectives
Illustrative photo, 25 kg white woven sacks of powder on a pallet in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Cephaloridine?

Plain description, key identifiers and synonyms

Cefaloridine is a cephalosporin compound having pyridinium-1-ylmethyl and 2-thienylacetamido side-groups. A first-generation semisynthetic derivative of cephalosporin C. It has a role as an antibacterial drug. It is a cephalosporin, a semisynthetic derivative and a beta-lactam antibiotic allergen.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
CAS number
50-59-9 CAS number cross-checked
EC number
200-052-6
Molecular formula
C19H17N3O4S2
UNII
LVZ1VC61HB
InChIKey
CZTQZXZIADLWOZ-CRAIPNDOSA-N
InChI
InChI=1S/C19H17N3O4S2/c23-14(9-13-5-4-8-27-13)20-15-17(24)22-16(19(25)26)12(11-28-18(15)22)10-21-6-2-1-3-7-21/h1-8,15,18H,9-11H2,(H-,20,23,25,26)/t15-,18-/m1/s1
Canonical SMILES
O=C(Cc1cccs1)NC1C(=O)N2C(C(=O)[O-])=C(C[n+]3ccccc3)CSC12
Isomeric SMILES
C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)CC3=CC=CS3)C(=O)[O-])C[N+]4=CC=CC=C4

Synonyms

  • cefaloridine
  • Cefaloridin
  • Cephaloridin
  • Cephaloridinum
  • Cephalomycine
  • Cefalorizin
  • Cepaloridin
  • Loridine
  • Cefaloridina
  • Ceflorin
  • Cepalorin
  • Kefloridin
  • Ceporin
  • Cefaloridinum
  • Glaxoridin
  • Ampligram
  • Ceporine
  • Deflorin
  • Keflodin
  • Keflordin
  • Ceporan
  • Kefspor
  • Sefacin
  • Betaine cephaloridine
  • Aliporina
Show all 39 synonyms
  • SCH 11527
  • LILLY 40602
  • CEPH 87/4
  • N-(7-(2'-Thienylacetamidoceph-3-ylmethyl))-pyridinium-2-carboxylate
  • N-(7-((2-Thienyl)acetamido)ceph-3-em-3-ylmethyl)pyridinium-4-carboxylate
  • 7-((2-Thienyl)acetamido)-3-(1-pyridylmethyl)cephalosporanic acid
  • (6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • 7-(Thiophene-2-acetamido)-3-(1-pyridylmethyl)-3-cephem-4-carboxylic acid betaine
  • 7-(alpha-(2-Thienyl)acetamido)-3-(1-pyridylmethyl)-3-cephem-4-carboxylic acid betaine
  • Pyridinium, 1-((2-carboxy-8-oxo-7-((2-thienylacetyl)amino)-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-, inner salt, (6R-trans)-
  • Pyridinium, 1-((2-carboxy-8-oxo-7-(2-(2-thienyl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-, hydroxide, inner salt
  • 3-(pyridinium-1-ylmethyl)-7beta-[(2-thienylacetyl)amino]-3,4-didehydrocepham-4-carboxylate
  • 3-(pyridinium-1-ylmethyl)-7beta-((2-thienylacetyl)amino)-3,4-didehydrocepham-4-carboxylate
  • (6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-((2-thiophen-2-ylacetyl)amino)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystalsexp.
Flash point
No dataexp.
Solubility
SOL IN WATERexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
415.50 g/molcalc.
Exact mass
415.066 Dacalc.
LogP (octanol/water)
-0.32calc.
Topological polar surface area
93.42 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
6calc.
Heavy atoms
28calc.
Rings
4calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.26calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(Cc1cccs1)NC1C(=O)N2C=C(C[n+]3ccccc3)CSC12

O=C(Cc1cccs1)NC1C(=O)N2C=C(C[n+]3ccccc3)CSC12

4 rings, 25 atoms.

11 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H317May cause an allergic skin reaction.
Precautionary statements (8)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Cephaloridine suppliers

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All 14 suppliers
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Where suppliers are based

14 suppliers in 5 countries

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Cephaloridine price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Veterinary medication:.

Pharmacological actions

  • Anti-Bacterial Agents

Roles

  • antibacterial agent
  • antibacterial drug
  • antiinfective agent
  • antimicrobial agent
  • antimicrobial drug
  • pharmaceutical

Pharmacology

Cephaloridine is a semisynthetic, broad-spectrum, first-generation cephalosporin with antibacterial activity. Cephaloridine binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

How it is made

Reaction of 7-aminocephalosporanic acid with thiophene acetyl chloride in acetone to form cephalothin, then heating with a thiocyanate, pyridine, and phosphoric acid, followed by ph adjustment with a mineral acid

Aq mixt of cephalothin, thiocyanate, pyridine, & phosphoric acid is heated for several hr. On cooling, diluting with water, & adjusting ph with mineral acid, cephaloridine thiocyanate salt precipitates which is purified & converted to cephaloridine by ph adjustment or by interaction with ion-exchange resin.

Cefalotin + pyridine (deacetylation)

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Cephaloridine is traded under.

HS 2941.90Indicative HS code

Antibiotics, other

World exports in 2024
$6.39B
+2.3% vs 2023, imports $6.97B
2019 to 2024
Top exporters
  1. China39.7%
  2. United States11.3%
  3. Switzerland * partner reported10.9%
Top importers
  1. Italy15.0%
  2. India * partner reported12.0%
  3. China8.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Cephaloridine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Cephaloridine, based on the data on this page

What is Cephaloridine?

Cefaloridine is a cephalosporin compound having pyridinium-1-ylmethyl and 2-thienylacetamido side-groups. A first-generation semisynthetic derivative of cephalosporin C. It has a role as an antibacterial drug. It is a cephalosporin, a semisynthetic derivative and a beta-lactam antibiotic allergen.

What is the CAS number of Cephaloridine?

The CAS registry number of Cephaloridine is 50-59-9.

What is the molecular formula and weight of Cephaloridine?

The molecular formula of Cephaloridine is C19H17N3O4S2 and its molar mass is 415.50 g/mol.

What is Cephaloridine used for?

Veterinary medication:.

Is Cephaloridine hazardous?

Cephaloridine carries the GHS signal word "Warning". Main hazards: may cause an allergic skin reaction. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Cephaloridine?

Cephaloridine is usually classified under HS code 294190 (Antibiotics, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Cephaloridine?

CompoundList lists 14 suppliers of Cephaloridine in China, United States, France, United Kingdom and 1 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Cephaloridine?

Suppliers quote Cephaloridine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Cephaloridine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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