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Respiratory, allergy and digestive drugs

Ciclesonide

Also known as Alvesco, Omnaris, Zetonna

CAS 126544-47-6Formula C32H44O7Molar mass 540.70 g/molEC 685-344-5
GHS signal word: Danger. Pictograms: Serious health hazard 70 suppliers listed Drug substance
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Ciclesonide chemical structure, C32H44O7, CAS 126544-47-6
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
126544-47-6
Formula
C32H44O7
Molar mass
540.70 g/mol
EC number
685-344-5
HS code
293729
Category
Respiratory, allergy and digestive drugs

What is Ciclesonide?

Plain description, key identifiers and synonyms

Ciclesonide is an organic molecular entity.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
[2-[(1S,2S,4R,6R,8S,9S,11S,12S,13R)-6-cyclohexyl-11-hydroxy-9,13-dimethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxoethyl] 2-methylpropanoate
CAS number
126544-47-6Other or deprecated CAS: 141845-82-1
EC number
685-344-5
Molecular formula
C32H44O7
UNII
S59502J185
InChIKey
LUKZNWIVRBCLON-GXOBDPJESA-N
InChI
InChI=1S/C32H44O7/c1-18(2)28(36)37-17-25(35)32-26(38-29(39-32)19-8-6-5-7-9-19)15-23-22-11-10-20-14-21(33)12-13-30(20,3)27(22)24(34)16-31(23,32)4/h12-14,18-19,22-24,26-27,29,34H,5-11,15-17H2,1-4H3/t22-,23-,24-,26+,27+,29+,30-,31-,32+/m0/s1
Canonical SMILES
CC(C)C(=O)OCC(=O)C12OC(C3CCCCC3)OC1CC1C3CCC4=CC(=O)C=CC4(C)C3C(O)CC12C
Isomeric SMILES
CC(C)C(=O)OCC(=O)[C@@]12[C@@H](C[C@@H]3[C@@]1(C[C@@H]([C@H]4[C@H]3CCC5=CC(=O)C=C[C@]45C)O)C)O[C@H](O2)C6CCCCC6

Synonyms

  • Alvesco
  • Omnaris
  • Zetonna
  • Ciclesonida
  • Alvesco 80
  • Alvesco 160
  • (R)-11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with cyclohexanecarboxaldehyde, 21-isobutyrate
  • ciclesonidum
  • Aservo EquiHaler
  • Ciclesonide (Standard)
  • 2-{6-cyclohexyl-11-hydroxy-9,13-dimethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosa-14,17-dien-8-yl}-2-oxoethyl 2-methylpropanoate
  • Osonase
  • Osonide
  • Omnair
  • RPR 251526
  • Alvesco HFA
  • Omnaris HFA
  • Alvesco (TN)
  • Omnaris (TN)
  • sobutyrate
  • Ciclesonide (JAN/USAN/INN)
  • Ciclesonide CRS
  • Zetonna (TN)
  • Alvesco, Ciclesonide
  • Ciclesonide 100 microg/mL in Acetonitrile
Show all 27 synonyms
  • el-87-6
  • Ciclesonide, >=98% (HPLC)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
540.70 g/molcalc.
Exact mass
540.3087 Dacalc.
LogP (octanol/water)
4.7calc.
Topological polar surface area
99.13 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
7calc.
Rotatable bonds
5calc.
Heavy atoms
39calc.
Rings
6calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.78calc.
Formal charge
0calc.
Stereocentres
9calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1C=CC2C(=C1)CCC1C2CCC2C1CC1OC(C3CCCCC3)OC12

O=C1C=CC2C(=C1)CCC1C2CCC2C1CC1OC(C3CCCCC3)OC12

6 rings, 27 atoms.

11 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H360May damage fertility or the unborn child.
  • H361Suspected of damaging fertility or the unborn child.
  • H361fdSuspected of damaging fertility. Suspected of damaging the unborn child.
  • H373May cause damage to organs through prolonged or repeated exposure.
  • H413May cause long lasting harmful effects to aquatic life.
Precautionary statements (8)
  • P203Obtain, read and follow all safety instructions before use.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Ciclesonide suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 70 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

70 suppliers in 13 countries

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Ciclesonide price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals, Animal Drugs.

Pharmacological actions

  • Anti-Allergic Agents
  • Glucocorticoids

Roles

  • anti-allergic agent
  • anti-asthmatic agent
  • antimicrobial agent
  • antiviral agent
  • nasal decongestant
  • pharmaceutical

Pharmacology

Ciclesonide is a nonhalogenated, synthetic, inhaled corticosteroid (ICS) with anti-inflammatory and potential antiviral activities. Upon administration by oral inhalation into the lungs, ciclesonide (CIC) is converted by local esterases to its active metabolite desisobutyryl-ciclesonide (des-CIC), which binds to intracellular glucocorticoid receptors (GRs). The ligand-bound GRs regulate gene expressions, which lead to inhibitory activities against multiple cell types, such as mast cells, eosinophils, basophils, lymphocytes, macrophages and neutrophils, and various mediators associated with inflammation, such as histamine, eicosanoids, leukotrienes and cytokines. In addition, ciclesonide may suppress the replication of human coronavirus by targeting viral nonstructural protein 15 (NSP15).

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ciclesonide is traded under.

HS 2937.29Indicative HS code

Steroidal hormones, their derivatives and structural analogues, other

World exports in 2024
$2.32B
+5.7% vs 2023, imports $2.41B
2019 to 2024
Top exporters
  1. Belgium25.3%
  2. United States24.9%
  3. China13.0%
Top importers
  1. Italy18.0%
  2. Canada13.0%
  3. Belgium12.2%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Ciclesonide is indicative (it is known at chapter level only). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ciclesonide, based on the data on this page

What is Ciclesonide?

Ciclesonide is an organic molecular entity.

What is the CAS number of Ciclesonide?

The CAS registry number of Ciclesonide is 126544-47-6. Other or deprecated CAS numbers: 141845-82-1.

What is the molecular formula and weight of Ciclesonide?

The molecular formula of Ciclesonide is C32H44O7 and its molar mass is 540.70 g/mol.

What is Ciclesonide used for?

Use classes: Pharmaceuticals, Animal Drugs.

Is Ciclesonide hazardous?

Ciclesonide carries the GHS signal word "Danger". Main hazards: may damage fertility or the unborn child, suspected of damaging fertility or the unborn child, suspected of damaging fertility. suspected of damaging the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Ciclesonide?

Ciclesonide is usually classified under HS code 293729 (Steroidal hormones, their derivatives and structural analogues, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ciclesonide?

CompoundList lists 70 suppliers of Ciclesonide in United States, China, India, Germany and 9 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Ciclesonide in India?

7 suppliers in India list Ciclesonide on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Ciclesonide?

Suppliers quote Ciclesonide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Ciclesonide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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