D-Glucosamine
Also known as glucosamine, 2-amino-2-deoxy-D-glucopyranose, chitosamine
Key facts
What buyers check first
- CAS number
- 3416-24-8
- Formula
- C6H13NO5
- Physical form
- Solid
- Melting point
- 88 °C
- HS code
- 293299
- Category
- Hair care agents
What is D-Glucosamine?
Plain description, key identifiers and synonyms
2-amino-2-deoxy-D-glucopyranose is a D-glucosamine whose structure comprises D-glucopyranose having an amino substituent at position 2. It has a role as a geroprotector, a mouse metabolite and an Escherichia coli metabolite. It is functionally related to a D-glucopyranose. It is a conjugate base of a 2-ammonio-2-deoxy-D-glucopyranose.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol
- CAS number
- 3416-24-8 CAS number cross-checkedOther or deprecated CAS: 90-77-7
- EC number
- 222-311-2
- Molecular formula
- C6H13NO5
- MDL number
- MFCD09025572
- INCI name
- GLUCOSAMINE
- InChIKey
- MSWZFWKMSRAUBD-IVMDWMLBSA-N
- InChI
- InChI=1S/C6H13NO5/c7-3-5(10)4(9)2(1-8)12-6(3)11/h2-6,8-11H,1,7H2/t2-,3-,4-,5-,6?/m1/s1
- Canonical SMILES
- NC1C(O)OC(CO)C(O)C1O
- Isomeric SMILES
- C([C@@H]1[C@H]([C@@H]([C@H](C(O1)O)N)O)O)O
Synonyms
- glucosamine
- 2-amino-2-deoxy-D-glucopyranose
- chitosamine
- (3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol
- Glucosamina
- Mediflex
- (3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)tetrahydro-2H-pyran-2,4,5-triol
- 2-Deoxy-2-amino-D-glucose
- D-GlcN
- 2-deoxy-2-amino-d-glucopyranose
- 2-Amino-2-deoxy-D-glucose
- 2-deoxy-2-amino-glucose
- 2-amino-2-deoxy-glucopyranose
- 2-Deoxy-2-Amino-Glucopyranose
- 2-amino-2-deoxy-glucopyranoside
- 2-Deoxy-2-Amino-Glucopyranoside
- 2-amino-2-deoxy-d-glucopyranoside
- 2-Deoxy-2-Amino-D-Glucopyranoside
- D-Glucopyranose, 2-deoxy-2-Amino-
- 2-Amino-2-deoxy-glucose
- glucosamin
- Glucosaminum
- D-Glucose, 2-amino-2-deoxy-
- Cidaflex
- Schiff
Show all 38 synonymsShow fewer synonyms
- Optiflex-G
- GlcN
- SNFG:GlcN
- GlcN (SNFG)
- 2 Amino 2 Deoxyglucose
- GlyTouCan:G80384UV
- (3S,4S,5R,6S)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol
- D-(+)-Glucosamine
- D-Glucopyranose, 2-amino-2-deoxy-
- Glucopyranose, 2-amino-2-deoxy-
- Glucopyranose, 2-amino-2-deoxy-, d-
- Glucosamine free base
- D-Glucosamine, Chitosamine
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Physical form | Solidexp.Measured value |
|---|---|
| Melting point | 88 °Cexp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 179.17 g/molcalc.Computed value |
|---|---|
| Exact mass | 179.0794 Dacalc.Computed value |
| LogP (octanol/water) | -3.25calc.Computed value |
| Topological polar surface area | 116.2 Ųcalc.Computed value |
| Hydrogen bond donors | 5calc.Computed value |
| Hydrogen bond acceptors | 6calc.Computed value |
| Rotatable bonds | 1calc.Computed value |
| Heavy atoms | 12calc.Computed value |
| Rings | 1calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 1calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 5calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
D-Glucosamine suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- ManufacturerUnclaimed profileGlucosamineGrade, purity and minimum order on requestPrice on request
- China ManufacturerUnclaimed profileGlucosamineGrade, purity and minimum order on requestPrice on request
- China ManufacturerUnclaimed profileGlucosamineGrade, purity and minimum order on requestPrice on request
- Price on request
- China, WuhanUnclaimed profileGlucosamineGrade, purity and minimum order on requestPrice on request
- India, MumbaiUnclaimed profileD-GlucosamineGrade, purity and minimum order on requestPrice on request
- United States, Watsonville ManufacturerUnclaimed profileSchiffGrade, purity and minimum order on requestPrice on request
- India, Ahmedabad ManufacturerUnclaimed profileGlucosamineGrade, purity and minimum order on requestPrice on request
- China, Huaian ManufacturerUnclaimed profileGlucosamineGrade, purity and minimum order on requestPrice on request
- United States, Lehi ManufacturerUnclaimed profileGlucosamineGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
103 suppliers in 25 countries
- China27
- United States23
- India12
- Spain6
- Germany4
- Netherlands3
- and 19 more countries
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D-Glucosamine price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Antiarthritic.
Biochemical research.
Pharmaceutic aid.
Use classes: Cosmetics.
Industries and functions
Cosmetic ingredient, INCI name GLUCOSAMINE(antistatic, hair conditioning)
Roles
- Escherichia coli metabolite
- animal metabolite
- bacterial metabolite
- eukaryotic metabolite
- geroprotector
- mammalian metabolite
- metabolite
- mouse metabolite
- pharmaceutical
- prokaryotic metabolite
- protective agent
Functional uses
- Anti-static agent
- Softener and conditioner
Cosmetic functions
- Antistatic
- Hair conditioning
Pharmacology
Glucosamine is a popular nutritional supplement and natural component of cartilage that is frequently combined with chondroitin sulfate and used for osteoarthritis and nonspecific joint pain. Glucosamine has been implicated in isolated case reports in causing clinically apparent liver injury, but the role of glucosamine as opposed to other herbal components or contaminants has not been shown, and liver injury due to glucosamine or chondroitin must be very rare if it occurs at all.
How it is made
Found in chitin, in mucoproteins, and in mucopolysaccharides.
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- EU cosmetic ingredient inventory
- Active ingredient in FDA approved drug labels
United States
- TSCA inventory (USA)Status: Active in US commerce
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code D-Glucosamine is traded under.
Heterocyclic compounds with oxygen hetero-atom(s) only, other
- China28.9%
- Switzerland * partner reported12.7%
- Germany7.8%
- United States49.7%
- China11.9%
- India * partner reported3.3%
* Partner reported figures, a lower bound.
The HS code shown for D-Glucosamine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Related chemicals
Parent and salt forms, stereoisomers, similar structures and isomers
Salt and hydrate forms
Records that share this compound as their parent
Stereoisomers and isotopic forms
Same connectivity, different stereochemistry or isotopes (same InChIKey skeleton)
Similar structures
Nearest neighbours by Morgan fingerprint Tanimoto similarity
Same formula isomers
Different compounds that share this molecular formula
Frequently asked questions
Quick answers about D-Glucosamine, based on the data on this page
What is D-Glucosamine?
What is D-Glucosamine used for?
Guides for buyers
Practical guides that help when you source, ship or handle D-Glucosamine
- Article, FormulationHow to choose a cosmetic emulsifierA structured way to choose an emulsifier for creams and lotions: emulsion type, HLB and its limits, emulsifier families, formula fit, stability testing and what to ask suppliers.Read
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
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