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Cardiovascular and metabolic drugs

Dipyridamole

Also known as Persantin, Dipyridamine, Persantine

CAS 58-32-2Formula C24H40N8O4Molar mass 504.64 g/molEC 200-374-7
GHS signal word: Warning. Pictograms: Harmful or irritant 129 suppliers listed Drug substance
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Dipyridamole chemical structure, C24H40N8O4, CAS 58-32-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
58-32-2
Formula
C24H40N8O4
Molar mass
504.64 g/mol
EC number
200-374-7
HS code
293359
Category
Cardiovascular and metabolic drugs

What is Dipyridamole?

Plain description, key identifiers and synonyms

Dipyridamole is a pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots. It has a role as a vasodilator agent, a platelet aggregation inhibitor, an adenosine phosphodiesterase inhibitor and an EC 3.5.4.4 (adenosine deaminase) inhibitor. It is a member of piperidines, a tetrol, a pyrimidopyrimidine and a tertiary amino compound.

Dipyridamole is a medication that inhibits blood clot formation[3] when given chronically and causes blood vessel dilation when given at high doses over a short time.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol
CAS number
58-32-2 CAS number cross-checked
EC number
200-374-7
Molecular formula
C24H40N8O4
UNII
64ALC7F90C
MDL number
MFCD00010555
InChIKey
IZEKFCXSFNUWAM-UHFFFAOYSA-N
InChI
InChI=1S/C24H40N8O4/c33-15-11-31(12-16-34)23-26-20-19(21(27-23)29-7-3-1-4-8-29)25-24(32(13-17-35)14-18-36)28-22(20)30-9-5-2-6-10-30/h33-36H,1-18H2
SMILES (canonical and isomeric)
C1CCN(CC1)C2=NC(=NC3=C2N=C(N=C3N4CCCCC4)N(CCO)CCO)N(CCO)CCO

Synonyms

  • Persantin
  • Dipyridamine
  • Persantine
  • Curantyl
  • Dipyudamine
  • Dipiridamol
  • Cleridium 150
  • Dypyridamol
  • Iv Persantine
  • Dipyridamolum
  • 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol
  • 2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(piperidin-1-yl)pyrimido[5,4-d][1,3]diazin-2-yl}(2-hydroxyethyl)amino)ethan-1-ol
  • Dipyramidole
  • Novo Dipiradol
  • Apo Dipyridamole
  • 2,2',2'',2'''-{[4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo}tetraethanol
  • dipiridamolo
  • Dipridamole
  • Pyridantin
  • Modaplate
  • Vasyrol
  • Attia
  • Persantin ret
  • Ofcram pr
  • Cerebrovase 25
Show all 38 synonyms
  • Cerebrovase 100
  • 2,2',2'',2'''-((4,8-Di(piperidin-1-yl)pyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetraethanol
  • 2-((2-(bis(2-hydroxyethyl)amino)-4,8-di(piperidin-1-yl)pyrimido(5,4-d)pyrimidin-6-yl)-(2-hydroxyethyl)amino)ethanol
  • 2-((6-(bis(2-hydroxyethyl)amino)-4,8-bis(piperidin-1-yl)pyrimido(5,4-d)(1,3)diazin-2-yl)(2-hydroxyethyl)amino)ethan-1-ol
  • 2,2',2'',2''''-((4,8-Dipiperidinopyrimido-(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetraethanol
  • Dipyridamol
  • Stenocardil
  • Stimolcardio
  • Cardioflux
  • Kurantil
  • Anginal
  • Apricor
  • Coribon

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
504.64 g/molcalc.
Exact mass
504.3173 Dacalc.
LogP (octanol/water)
-0.02calc.
Topological polar surface area
145.4 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
12calc.
Rotatable bonds
12calc.
Heavy atoms
36calc.
Rings
4calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.75calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1nc(N2CCCCC2)c2ncnc(N3CCCCC3)c2n1

c1nc(N2CCCCC2)c2ncnc(N3CCCCC3)c2n1

4 rings, 22 atoms.

22 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Dipyridamole suppliers

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All 129 suppliers
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Where suppliers are based

129 suppliers in 17 countries

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Dipyridamole price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Phosphodiesterase Inhibitors
  • Platelet Aggregation Inhibitors
  • Vasodilator Agents

Roles

  • adenosine phosphodiesterase inhibitor
  • anti-HIV agent
  • anti-anaemic agent
  • anticoagulant
  • antihypertensive agent
  • antimicrobial agent
  • antineoplastic agent
  • antirheumatic drug
  • antiviral agent
  • cardiovascular drug
  • enzyme inhibitor
  • hematologic agent
  • pharmaceutical
  • platelet aggregation inhibitor
  • vasodilator agent

Functional uses

  • Pharmaceutical

Pharmacology

Dipyridamole is a Platelet Aggregation Inhibitor. The physiologic effect of dipyridamole is by means of Decreased Platelet Aggregation.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Dipyridamole is traded under.

HS 2933.59Indicative HS code

Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring, other

World exports in 2024
$18.4B
+10.5% vs 2023, imports $24.8B
2019 to 2024
Top exporters
  1. Ireland43.6%
  2. Switzerland * partner reported26.3%
  3. China7.9%
Top importers
  1. Slovenia30.3%
  2. United States30.1%
  3. Germany15.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Dipyridamole is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Dipyridamole, based on the data on this page

What is Dipyridamole?

Dipyridamole is a pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

What is the CAS number of Dipyridamole?

The CAS registry number of Dipyridamole is 58-32-2.

What is the molecular formula and weight of Dipyridamole?

The molecular formula of Dipyridamole is C24H40N8O4 and its molar mass is 504.64 g/mol.

What is Dipyridamole used for?

Use classes: Pharmaceuticals.

Is Dipyridamole hazardous?

Dipyridamole carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Dipyridamole?

Dipyridamole is usually classified under HS code 293359 (Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Dipyridamole?

CompoundList lists 129 suppliers of Dipyridamole in China, United States, India, Germany and 13 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Dipyridamole in India?

18 suppliers in India list Dipyridamole on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Dipyridamole?

Suppliers quote Dipyridamole on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Dipyridamole

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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