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Skin conditioning agents and actives

Dodecanedioic acid

Also known as 1,12-Dodecanedioic acid, 1,10-Decanedicarboxylic acid, Decamethylenedicarboxylic acid

CAS 693-23-2Formula C12H22O4Molar mass 230.30 g/molEC 211-746-3
GHS signal word: Warning. Pictograms: Harmful or irritant 47 suppliers listed
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Dodecanedioic acid chemical structure, C12H22O4, CAS 693-23-2
2D chemical structure

Key facts

What buyers check first

All properties
Physical form
Liquid
Melting point
130 to 132
Solubility
SOL IN HOT TOLUENE, ALC, HOT ACETIC ACID, SLIGHTLY SOL IN HOT WATER
HS code
291719
Category
Skin conditioning agents and actives
Illustrative photo, assorted laboratory chemical bottles and jars on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Dodecanedioic acid?

Plain description, key identifiers and synonyms

Dodecanedioic acid is an alpha,-dicarboxylic acid that is dodecane in which the methyl groups have been oxidised to the corresponding carboxylic acids. It has a role as an EC 1.1.1.1 (alcohol dehydrogenase) inhibitor and a human metabolite. It is a dicarboxylic fatty acid and an alpha,omega-dicarboxylic acid. It is a conjugate acid of a dodecanedioate(2-). It derives from a hydride of a dodecane.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
dodecanedioic acid
CAS number
693-23-2 CAS number cross-checkedOther or deprecated CAS: 142610-44-4, 53037-60-8
EC number
211-746-3
Molecular formula
C12H22O4
UNII
978YU42Q6I
MDL number
MFCD00002735
INCI name
DODECANEDIOIC ACID
InChIKey
TVIDDXQYHWJXFK-UHFFFAOYSA-N
InChI
InChI=1S/C12H22O4/c13-11(14)9-7-5-3-1-2-4-6-8-10-12(15)16/h1-10H2,(H,13,14)(H,15,16)
SMILES (canonical and isomeric)
C(CCCCCC(=O)O)CCCCC(=O)O

Synonyms

  • 1,12-Dodecanedioic acid
  • 1,10-Decanedicarboxylic acid
  • Decamethylenedicarboxylic acid
  • 1,10-Dicarboxydecane
  • dodecandioic acid
  • n-Dodecanedioic acid
  • 1.10-Decanedic
  • Dodecanedioicacid
  • n-Dodecanedioate
  • Decane-1,10-dicarboxylic acid
  • Twelve alkyl acid
  • dodecane dioic acid
  • Corfree M 2
  • 1,12-Dodecanedioate
  • n-Dodecane-a,w-dioate
  • 1,10-dicarboxy decane
  • SL-AH
  • Decamethylenedicarboxylate
  • 1,10-Decanedicarboxylate
  • Dodecanedioic acid, 99%
  • n-Dodecane-a,w-dioic acid
  • Dodecanedioic acid (NIST)
  • Dodecanedioic acid, Refined
  • 1, 10-Decanedicarboxylic acid
  • n-Dodecane-alpha,omega-dioic acid

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Physical form
Liquidexp.
Melting point
130 to 132exp.
Solubility
SOL IN HOT TOLUENE, ALC, HOT ACETIC ACID, SLIGHTLY SOL IN HOT WATERexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
230.30 g/molcalc.
Exact mass
230.1518 Dacalc.
LogP (octanol/water)
3.06calc.
Topological polar surface area
74.6 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
11calc.
Heavy atoms
16calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.83calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
Precautionary statements (9)
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Dodecanedioic acid suppliers

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All 47 suppliers
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Where suppliers are based

47 suppliers in 12 countries

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Dodecanedioic acid price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Intermediate.

Industrial uses: Intermediate, Corrosion inhibitor, Plasticizer, Monomers, Lubricating agent, Wetting agent (non-aqueous), Binder.

Consumer uses: Anti-freeze agent.

Cosmetic ingredient, INCI name DODECANEDIOIC ACID(skin conditioning)

Roles

  • animal metabolite
  • enzyme inhibitor
  • eukaryotic metabolite
  • human metabolite
  • mammalian metabolite
  • metabolite

Functional uses

  • Chemical reaction regulator
  • Corrosion inhibitor
  • Flow promoter
  • Softener and conditioner

Cosmetic functions

  • Skin conditioning

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Dodecanedioic acid is traded under.

HS 2917.19Indicative HS code

Acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and…

World exports in 2024
$718M
+8.1% vs 2023, imports $915M
2019 to 2024
Top exporters
  1. China46.6%
  2. United States13.7%
  3. Germany10.1%
Top importers
  1. United States16.2%
  2. Denmark11.8%
  3. Germany10.0%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Dodecanedioic acid is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Dodecanedioic acid, based on the data on this page

What is Dodecanedioic acid?

Dodecanedioic acid is an alpha,-dicarboxylic acid that is dodecane in which the methyl groups have been oxidised to the corresponding carboxylic acids. It has a role as an EC 1.1.1.1 (alcohol dehydrogenase) inhibitor and a human metabolite. It is a dicarboxylic fatty acid and an alpha,omega-dicarboxylic acid.

What is the CAS number of Dodecanedioic acid?

The CAS registry number of Dodecanedioic acid is 693-23-2. Other or deprecated CAS numbers: 142610-44-4, 53037-60-8.

What is the molecular formula and weight of Dodecanedioic acid?

The molecular formula of Dodecanedioic acid is C12H22O4 and its molar mass is 230.30 g/mol.

What is Dodecanedioic acid used for?

Intermediate. Industrial uses: Intermediate, Corrosion inhibitor, Plasticizer, Monomers, Lubricating agent, Wetting agent (non-aqueous), Binder. Consumer uses: Anti-freeze agent.

Is Dodecanedioic acid hazardous?

Dodecanedioic acid carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Dodecanedioic acid?

Dodecanedioic acid is usually classified under HS code 291719 (Acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Dodecanedioic acid?

CompoundList lists 47 suppliers of Dodecanedioic acid in China, United States, Germany, Italy and 8 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Dodecanedioic acid?

Suppliers quote Dodecanedioic acid on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Dodecanedioic acid

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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