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Other active pharmaceutical ingredients

Echothiophate iodide

Also known as Ecothiopate iodide, Echodide, Ecothiophate iodide

CAS 513-10-0Formula C9H23INO3PSMolar mass 383.23 g/molEC 208-152-1
1 supplier listed Drug substance
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Echothiophate iodide chemical structure, C9H23INO3PS, CAS 513-10-0
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
513-10-0
Formula
C9H23INO3PS
Molar mass
383.23 g/mol
EC number
208-152-1
HS code
293090
Category
Other active pharmaceutical ingredients

What is Echothiophate iodide?

Plain description, key identifiers and synonyms

Ecothiopate iodide is the iodide salt of ecothiopate. An irreversible acetylcholinesterase inhibitor, it is used an ocular antihypertensive in the treatment of open-angle glaucoma, particularly when other drugs have proved inadequate. It has a role as an EC 3.1.1.8 (cholinesterase) inhibitor, an antiglaucoma drug and a miotic. It is an iodide salt and a quaternary ammonium salt. It contains an ecothiopate.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-diethoxyphosphorylsulfanylethyl(trimethyl)azanium iodide
CAS number
513-10-0 CAS number cross-checked
EC number
208-152-1
Molecular formula
C9H23INO3PS
UNII
BA9QH3P00T
InChIKey
OVXQHPWHMXOFRD-UHFFFAOYSA-M
InChI
InChI=1S/C9H23NO3PS.HI/c1-6-12-14(11,13-7-2)15-9-8-10(3,4)5;/h6-9H2,1-5H3;1H/q+1;/p-1
SMILES (canonical and isomeric)
CCOP(=O)(OCC)SCC[N+](C)(C)C.[I-]

Synonyms

  • Ecothiopate iodide
  • Echodide
  • Ecothiophate iodide
  • Ecothiopati iodidum
  • Phospholine iodide
  • Iodure d'ecothiopate
  • Ioduro de ecotiopato
  • 217-mi
  • Diethoxyphosphoryl-thiocholine iodide
  • Echothiophate iodide (USP)
  • 2-Diethoxy-phosphinylthioethyl-trimethylammonium iodide
  • Ethanaminium, 2-((diethoxyphosphinyl)thio)-N,N,N-trimethyl-, iodide
  • N-(2-(Diethoxyphosphinylthio)ethyl)trimethylammonium iodide
  • O,O-Diethyl S-2-trimethylammonium ethylphosphonothiolate iodide
  • S-(2-(N,N,N-Trimethylammonio)ethyl) O,O-diethylphosphorothiolate iodide
  • (2-Mercaptoethyl)trimethylammonium iodide S-ester with O,O-diethyl phosphorothioate
  • Ecostigmine iodide
  • Ammonium, (2-mercaptoethyl)trimethyl-, iodide, S-ester with O,O-diethylphosphorothioate
  • 2-((Diethoxyphosphinyl)thio)-N,N,N,-trimethylethanaminium iodide
  • Iodide, Ecothiopate
  • Iodide, Phospholine
  • Iodide, Ecothiophate
  • Iodide, Echothiophate
  • Ethanaminium, 2-[(diethoxyphosphinyl)thio]-N,N,N-trimethyl-, iodide
  • Acothiopate (cation)
Show all 33 synonyms
  • Echothiophate iodide for ophthalmic solution
  • 2-(Diethoxyphosphorylsulfanyl)-N,N,N-trimethylethylaminium iodide
  • (2-Mercaptoethyl)trimethylammonium Iodide S-ester with O,O-diethyl Phosphorothioate, Diethoxyphosphoryl-thiocholine Iodide
  • Echothiopate iodide
  • Ecostigmini jodidum
  • 2-diethoxyphosphorylsulfanylethyl(trimethyl)azanium, iodide
  • Phospholine (the pharmaceutical)
  • 217 MI

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
383.23 g/molcalc.
Exact mass
383.0181 Dacalc.
LogP (octanol/water)
-0.39calc.
Topological polar surface area
35.53 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
8calc.
Heavy atoms
16calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
0calc.
Components
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Echothiophate iodide suppliers

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Echothiophate iodide price

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Cholinesterase Inhibitors
  • Miotics
  • Parasympathomimetics

Roles

  • antiglaucoma drug
  • enzyme inhibitor
  • miotic
  • neurotransmitter agent
  • ophthalmology drug
  • pharmaceutical

Pharmacology

Echothiophate Iodide is the iodide salt form of echothiophate, a long-acting cholinesterase inhibitor with parasympathomimetic activity. Echothiophate iodide potentiates the action of endogenous acetylcholine by inhibiting acetylcholinesterase that hydrolyzes acetylcholine. When applied topically to the eye, this agent prolongs stimulation of the parasympathetic receptors at the neuromuscular junctions of the longitudinal muscle of the ciliary body. Contraction of longitudinal muscle pulls on the scleral spur, and opens the trabecular meshwork, thereby increases aqueous humor outflow from the eye and reduces intraocular pressure.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Echothiophate iodide is traded under.

HS 2930.90Indicative HS code

Organo-sulphur compounds, other

World exports in 2024
$5.83B
+0.1% vs 2023, imports $5.93B
2019 to 2024
Top exporters
  1. China40.7%
  2. United States10.9%
  3. Japan9.3%
Top importers
  1. United States13.3%
  2. Brazil12.6%
  3. China6.6%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Echothiophate iodide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Echothiophate iodide, based on the data on this page

What is Echothiophate iodide?

Ecothiopate iodide is the iodide salt of ecothiopate. An irreversible acetylcholinesterase inhibitor, it is used an ocular antihypertensive in the treatment of open-angle glaucoma, particularly when other drugs have proved inadequate.

What is the CAS number of Echothiophate iodide?

The CAS registry number of Echothiophate iodide is 513-10-0.

What is the molecular formula and weight of Echothiophate iodide?

The molecular formula of Echothiophate iodide is C9H23INO3PS and its molar mass is 383.23 g/mol.

What is Echothiophate iodide used for?

Known uses and roles of Echothiophate iodide include antiglaucoma drug, enzyme inhibitor, miotic, neurotransmitter agent, ophthalmology drug and 4 more.

Is Echothiophate iodide hazardous?

No GHS hazard classification for Echothiophate iodide is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Echothiophate iodide?

Echothiophate iodide is usually classified under HS code 293090 (Organo-sulphur compounds, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Echothiophate iodide?

CompoundList lists 1 supplier of Echothiophate iodide in United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Echothiophate iodide?

Suppliers quote Echothiophate iodide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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