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Cationic surfactants

Edelfosine

Also known as ET-18-OMe, 1-O-Octadecyl-2-O-methyl-rac-glycero-3-phosphocholine, Edelfosina

CAS 70641-51-9Formula C27H58NO6PMolar mass 523.74 g/mol
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Edelfosine chemical structure, C27H58NO6P, CAS 70641-51-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
70641-51-9
Formula
C27H58NO6P
Molar mass
523.74 g/mol
HS code
292390
Category
Cationic surfactants

What is Edelfosine?

Plain description, key identifiers and synonyms

1-octadecyl-2-methylglycero-3-phosphocholine is a glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2-methoxy-3-octadecoxypropyl) 2-(trimethylazaniumyl)ethyl phosphate
CAS number
70641-51-9 CAS number cross-checkedOther or deprecated CAS: 65492-82-2
Molecular formula
C27H58NO6P
UNII
1Y6SNA8L5S
MDL number
MFCD00135190
InChIKey
MHFRGQHAERHWKZ-UHFFFAOYSA-N
InChI
InChI=1S/C27H58NO6P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-23-32-25-27(31-5)26-34-35(29,30)33-24-22-28(2,3)4/h27H,6-26H2,1-5H3
SMILES (canonical and isomeric)
CCCCCCCCCCCCCCCCCCOCC(COP(=O)([O-])OCC[N+](C)(C)C)OC

Synonyms

  • ET-18-OMe
  • 1-O-Octadecyl-2-O-methyl-rac-glycero-3-phosphocholine
  • Edelfosina
  • Edelfosinum
  • ET 18-OCH3
  • 1-Octadecyl-2-methylglycero-3-phosphocholine
  • Racemic 1-O-octadecyl-2-O-methylglycero-3-phosphocholine
  • 1-Octadecyl-2-methylglycero-3-phosphorylcholine
  • rac-1-Octadecyl-2-methoxyglycero-3-phosphocholine
  • 1-O-Octadecyl-2-O-methyl-rac-glyceryl-3-phosphorylcholine
  • ET-18-O-Methyl
  • 1-Octadecyl-2-methyl-sn-glycero-3-phosphocholine
  • ET18-Ome
  • 2-methoxy-PAF
  • ET-18-Och(3)
  • 1-O-Octadecyl-2-methyl-3-phosphatidylcholine
  • 1-Octadecyl-2-methoxyglycero-3-phosphorylcholine
  • 1-Octadecyl-2-methoxy-sn-glycero-3-phosphorylcholine
  • 1-O-octadecyl-2-O-methylglycerophosphocholine
  • 1-O-octadecyl-2-O-methyl-glycero-phosphocholine
  • 1-Octadecyl-2-methoxy-rac-glycero-3-phosphocholine
  • Et-18-OCH3
  • Ro 14-5243
  • 2-methoxy-3-(octadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate
  • NIOSH/GA4029000
Show all 35 synonyms
  • (2-methoxy-3-octadecoxypropyl) 2-(trimethylazaniumyl)ethyl phosphate
  • 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, hydroxide, inner salt, 4-oxide, (+-)-
  • 2-methoxy-3-(octadecyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate
  • rac-1-Octadecyl-2-methoxy-glycerophosphocholine
  • Choline hydroxide, (+-)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate, inner salt
  • Choline hydroxide, 2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate, inner salt
  • 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, inner salt, 4-oxide, (+/-)-
  • 1-Octadecyl-2-methylphosphorylcholine
  • Choline, 1-octadecyl-2-methoxy-3-phosphoryl-
  • Phosphorylcholine, 1-octadecyl-2-methyl- (alp)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
523.74 g/molcalc.
Exact mass
523.4002 Dacalc.
LogP (octanol/water)
6.49calc.
Topological polar surface area
77.05 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
27calc.
Heavy atoms
35calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Edelfosine suppliers

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All 4 suppliers
4 of 4 offers

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Where suppliers are based

4 suppliers in 2 countries

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Edelfosine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Industries and functions

Pharmacological actions

  • Antineoplastic Agents
  • Phosphodiesterase Inhibitors

Pharmacology

Edelfosine is a synthetic analog of lysophosphatidylcholine, an ether lipid, possessing anti-leishmanial and antineoplastic activity. The mechanism of action for edelfosine has not been fully elucidated. Targeting cellular membranes, edelfosine modulates membrane permeability, membrane lipid composition, and phospholipid metabolism. Edelfosine also inhibits the phosphatidylinositol 3 kinase (PI3K)-AKT/PKB survival pathway, possibly activating the pro-apoptotic stress-activated protein kinase (SAPK/JNK) pathways, thereby inducing apoptosis. In addition, this agent inhibits protein kinase C, intracellular activation of the Fas/CD95 receptor, and intracellular acidification. Anti-leishmanial activity may be due to inhibition of a glycosomal alkyl-specific-acylCoA acyltransferase. (NCI)

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Edelfosine is traded under.

HS 2923.90Indicative HS code

Quaternary ammonium salts and hydroxides whether or not chemically defined not elsewhere classified…

World exports in 2024
$1.07B
+14.4% vs 2023, imports $1.16B
2019 to 2024
Top exporters
  1. China36.7%
  2. United States14.2%
  3. Netherlands9.4%
Top importers
  1. South Korea10.7%
  2. Germany10.1%
  3. United States9.9%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Edelfosine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Edelfosine, based on the data on this page

What is Edelfosine?

1-octadecyl-2-methylglycero-3-phosphocholine is a glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.

What is the CAS number of Edelfosine?

The CAS registry number of Edelfosine is 70641-51-9. Other or deprecated CAS numbers: 65492-82-2.

What is the molecular formula and weight of Edelfosine?

The molecular formula of Edelfosine is C27H58NO6P and its molar mass is 523.74 g/mol.

What is Edelfosine used for?

Known uses and roles of Edelfosine include surfactants in home care and cleaning, antineoplastic agents and phosphodiesterase inhibitors.

Is Edelfosine hazardous?

No GHS hazard classification for Edelfosine is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Edelfosine?

Edelfosine is usually classified under HS code 292390 (Quaternary ammonium salts and hydroxides, lecithins and other phosphoaminolipids…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Edelfosine?

CompoundList lists 4 suppliers of Edelfosine in United States and China. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Edelfosine?

Suppliers quote Edelfosine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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