CompoundList
Sign in
Cosmetic antioxidants

Equol

Also known as (S)-Equol, (-)-(S)-Equol, (-)-Equol

CAS 531-95-3Formula C15H14O3Molar mass 242.27 g/molEC 208-522-2
33 suppliers listed
Get quotes Compare 33 suppliers
Equol chemical structure, C15H14O3, CAS 531-95-3
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
531-95-3
Formula
C15H14O3
Molar mass
242.27 g/mol
EC number
208-522-2
HS code
293299
Category
Cosmetic antioxidants

What is Equol?

Plain description, key identifiers and synonyms

Equol is a member of hydroxyisoflavans.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(3S)-3-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-ol
CAS number
531-95-3 CAS number cross-checkedOther or deprecated CAS: 94105-90-5
EC numbers
208-522-2, 618-999-2
Molecular formula
C15H14O3
UNII
2T6D2HPX7Q
MDL number
MFCD00200962
INCI name
EQUOL
InChIKey
ADFCQWZHKCXPAJ-GFCCVEGCSA-N
InChI
InChI=1S/C15H14O3/c16-13-4-1-10(2-5-13)12-7-11-3-6-14(17)8-15(11)18-9-12/h1-6,8,12,16-17H,7,9H2/t12-/m1/s1
Canonical SMILES
Oc1ccc(C2COc3cc(O)ccc3C2)cc1
Isomeric SMILES
C1[C@H](COC2=C1C=CC(=C2)O)C3=CC=C(C=C3)O

Synonyms

  • (S)-Equol
  • (-)-(S)-Equol
  • (-)-Equol
  • S-Equol
  • 2H-1-Benzopyran-7-ol, 3,4-dihydro-3-(4-hydroxyphenyl)-, (3S)-
  • 4',7-Dihydroxyisoflavan
  • 4',7-Isoflavandiol
  • (S)-(-)-4',7-Isoflavandiol
  • (3S)-3-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol
  • (3S)-3-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-ol
  • (3S)-3,4-Dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol
  • 3' Hydroxy Equol
  • 6' Hydroxy Equol
  • 4' O Methyl Equol
  • Equol, 4'-O-Methyl
  • 4' methoxy 7 isoflavanol
  • (S)-3-(4-Hydroxyphenyl)chroman-7-ol
  • (S)-3,4-Dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol
  • (3S)-3-(4-hydroxyphenyl)chroman-7-ol
  • 7,4'-Isoflavandiol
  • (3S)-Equol
  • Equol, (-)-
  • 3-(4-Hydroxy-phenyl)-chroman-7-ol
  • (S)-3-(4-Hydroxy-phenyl)-chroman-7-ol
  • (?)-Equol
Show all 33 synonyms
  • EQUOL (S)-FORM
  • SE 5OH
  • EQUOL, (S)-
  • AUS 131
  • 3,4-Dihydro-3-(4-hydroxyphenyl)-(S)-2H-1-benzopyran-7-ol
  • S-Equol, >=97% (HPLC)
  • (3s)-3-(4-hydroxyphenyl)-7-chromanol
  • (S)-3,4-Dihydro-3-(4-hydroxyphenyl)-2H-1-be

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
242.27 g/molcalc.
Exact mass
242.0943 Dacalc.
LogP (octanol/water)
2.82calc.
Topological polar surface area
49.69 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
1calc.
Heavy atoms
18calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.2calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(C2COc3ccccc3C2)cc1

c1ccc(C2COc3ccccc3C2)cc1

3 rings, 16 atoms, the Isoflavan ring system.

92 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Equol suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 33 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

33 suppliers in 7 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

Equol price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name EQUOL(antioxidant, hair conditioning, skin conditioning)

Pharmacological actions

  • Phytoestrogens

Roles

  • antineoplastic agent
  • pharmaceutical

Functional uses

  • Antioxidant
  • Softener and conditioner

Cosmetic functions

  • Antioxidant
  • Hair conditioning
  • Skin conditioning

Pharmacology

S-equol is an orally bioavailable, non-steroidal estrogen naturally produced by the metabolism of the isoflavonoid daidzein by human intestinal microflora, with potential chemoprotective and estrogen receptor (ER) modulating activities. S-equol preferentially binds to and activates the beta isoform of ER in certain target tissues, while having an antagonistic effect in other tissues. This modulates the expression of ER-responsive genes in a tissue-specific manner.

Read more

This agent may increase bone mineral density, affect vasomotor symptoms, and may decrease the proliferation rate of susceptible cancer cells. In addition, this agent interferes with the activity of enzymes involved in steroid biosynthesis. S-equol inhibits dihydrotestosterone (DHT) production and may inhibit the proliferation of androgen-driven prostate cancer. S-equol is the biologically active enantiomer while R-equol is essentially inactive and has a weak affinity for alpha-ER.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Equol is traded under.

HS 2932.99Indicative HS code

Heterocyclic compounds with oxygen hetero-atom(s) only, other

World exports in 2024
$3.81B
+10.3% vs 2023, imports $7.05B
2019 to 2024
Top exporters
  1. China28.9%
  2. Switzerland * partner reported12.7%
  3. Germany7.8%
Top importers
  1. United States49.7%
  2. China11.9%
  3. India * partner reported3.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Equol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Equol, based on the data on this page

What is Equol?

Equol is a member of hydroxyisoflavans.

What is the CAS number of Equol?

The CAS registry number of Equol is 531-95-3. Other or deprecated CAS numbers: 94105-90-5.

What is the molecular formula and weight of Equol?

The molecular formula of Equol is C15H14O3 and its molar mass is 242.27 g/mol.

What is Equol used for?

Known uses and roles of Equol include antioxidants in cosmetics and personal care, skin conditioning agents in cosmetics and personal care, hair conditioning agents in cosmetics and personal care, antineoplastic agent, pharmaceutical and 5 more.

Is Equol hazardous?

No GHS hazard classification for Equol is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Equol?

Equol is usually classified under HS code 293299 (Heterocyclic compounds with oxygen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Equol?

CompoundList lists 33 suppliers of Equol in China, United States, Belgium, Germany and 3 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Equol?

Suppliers quote Equol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Equol

Get quotes for Equol

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Equol
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Equol with a 3D view, its CAS number and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/equol-531-95-3" title="Equol structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Cosmetic antioxidants or HS code 293299

33 suppliers
Free quotes, contact stays private
Get quotes