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Dye intermediates

Ethylmorpholine

Also known as 4-Ethylmorpholine, N-Ethylmorpholine, Morpholine, 4-ethyl-

CAS 100-74-3Formula C6H13NOMolar mass 115.18 g/molEC 202-885-0
GHS signal word: Danger. Pictograms: Flammable, Corrosive, Acute toxicity (severe), Harmful or irritant 16 suppliers listed
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Ethylmorpholine chemical structure, C6H13NO, CAS 100-74-3
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Colorless liquid
Melting point
-62.8 °C
Boiling point
138 to 139
Density
Relative density (water = 1): 0.99
Flash point
32 °C
HS code
293499
Category
Dye intermediates
UN number
UN 1993
Illustrative photo, an amber glass solvent bottle with clear liquid on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Ethylmorpholine?

Plain description, key identifiers and synonyms

N-ethyl morpholine appears as a colorless liquid with a strong ammonia-like odor. Severely irritates skin, eyes, and mucous membranes. Moderately soluble in water and less dense than water. Flash point 83 °F.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-ethylmorpholine
CAS number
100-74-3 CAS number cross-checked
EC number
202-885-0
Molecular formula
C6H13NO
UNII
ECM0G991FQ
MDL number
MFCD00006177
InChIKey
HVCNXQOWACZAFN-UHFFFAOYSA-N
InChI
InChI=1S/C6H13NO/c1-2-7-3-5-8-6-4-7/h2-6H2,1H3
SMILES (canonical and isomeric)
CCN1CCOCC1

Synonyms

  • 4-Ethylmorpholine
  • N-Ethylmorpholine
  • Morpholine, 4-ethyl-
  • N-Ethylmorfolin
  • N-ethyl morpholine
  • 4-ethyl-morpholine
  • N-ethyl-morpholine
  • N-ethylmopholine
  • N-ethyhnorpholine
  • Texacat NEM
  • Toyocat NEM
  • 4-ethylmorpholirie
  • Dabco NEM
  • morpholine, N-ethyl-
  • 4-Ethylmorpholine, 97%
  • 4-27-00-00023 (Beilstein Handbook Reference)
  • N-Ethylmorpholine, reag
  • 4-Ethylmorpholine, >=97.0% (GC)
  • 4-Ethylmorpholine, BioXtra, suitable for protein sequencing, >=99.5% (GC)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless liquidexp.
Odour
AMMONIACAL ODORexp.
Melting point
-62.8 °Cexp.
Boiling point
138 to 139exp.
Density
Relative density (water = 1): 0.99exp.
Flash point
32 °Cexp.
Autoignition temperature
185 °Cexp.
Solubility
SOL IN ALL PROPORTIONS IN WATER, ETHANOL & ETHER, SOL IN ACETONEexp.
Vapour pressure
6.1 MM HG @ 20 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
115.18 g/molcalc.
Exact mass
115.0997 Dacalc.
LogP (octanol/water)
0.34calc.
Topological polar surface area
12.47 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
1calc.
Heavy atoms
8calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1COCCN1

C1COCCN1

1 ring, 6 atoms, the Morpholine ring system.

5,994 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS02: Flammable
Flammable
GHS05: Corrosive
Corrosive
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant
320NFPA 704 rating

Hazard statements

  • H226Flammable liquid and vapour.
  • H302 + H312 + H332Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled.
  • H302Harmful if swallowed.
  • H311Toxic in contact with skin.
  • H312Harmful in contact with skin.
  • H314Causes severe skin burns and eye damage.
  • H315Causes skin irritation.
  • H318Causes serious eye damage.
  • H319Causes serious eye irritation.
  • H332Harmful if inhaled.
  • H335May cause respiratory irritation.
Precautionary statements (37)
  • P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P233Keep container tightly closed.
  • P240Ground and bond container and receiving equipment.
  • P241Use explosion-proof electrical, ventilating and lighting equipment.
  • P242Use non-sparking tools.
  • P243Take action to prevent static discharges.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P262Do not get in eyes, on skin, or on clothing.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P301 + P330 + P331If swallowed: Rinse mouth. Do not induce vomiting.
  • P302 + P352If on skin: Wash with plenty of water.
  • P302 + P361 + P354If on skin: Take off immediately all contaminated clothing. Immediately rinse with water for several minutes.
  • P303 + P361 + P353If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P316Get emergency medical help immediately.
  • P317Get medical help.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P363Wash contaminated clothing before reuse.
  • P370 + P378In case of fire: Use appropriate media to extinguish.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P403 + P235Store in a well-ventilated place. Keep cool.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 1993
Transport hazard class
3
Packing group
III

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Ethylmorpholine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 16 suppliers
16 of 16 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

16 suppliers in 6 countries

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Ethylmorpholine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Urethane foam catalyst.

Intermediate for dyestuffs, pharmaceuticals, rubber accelerators & emulsifying agents, solvent for dyes, resins, oils.

Commonly used substrate for enzyme reactions.

Industrial uses: Catalyst.

Consumer uses: Catalyst.

Functional uses

  • Catalyst

How it is made

Reaction of morpholine with diethyl sulfate

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ethylmorpholine is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Ethylmorpholine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ethylmorpholine, based on the data on this page

What is Ethylmorpholine?

N-ethyl morpholine appears as a colorless liquid with a strong ammonia-like odor. Severely irritates skin, eyes, and mucous membranes. Moderately soluble in water and less dense than water. Flash point 83 °F.

What is the CAS number of Ethylmorpholine?

The CAS registry number of Ethylmorpholine is 100-74-3.

What is the molecular formula and weight of Ethylmorpholine?

The molecular formula of Ethylmorpholine is C6H13NO and its molar mass is 115.18 g/mol.

What is Ethylmorpholine used for?

Urethane foam catalyst. Intermediate for dyestuffs, pharmaceuticals, rubber accelerators & emulsifying agents, solvent for dyes, resins, oils. Commonly used substrate for enzyme reactions. Industrial uses: Catalyst. Consumer uses: Catalyst.

Is Ethylmorpholine hazardous?

Ethylmorpholine carries the GHS signal word "Danger". Main hazards: flammable liquid and vapour, harmful if swallowed. harmful in contact with skin. harmful if inhaled, harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Ethylmorpholine?

Ethylmorpholine is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ethylmorpholine?

CompoundList lists 16 suppliers of Ethylmorpholine in China, India, United States, Canada and 2 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Ethylmorpholine in India?

4 suppliers in India list Ethylmorpholine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Ethylmorpholine?

Suppliers quote Ethylmorpholine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Ethylmorpholine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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