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Cardiovascular and metabolic drugs

Fenofibrate

Also known as Procetofen, Tricor, Lipantil

CAS 49562-28-9Formula C20H21ClO4Molar mass 360.84 g/molEC 256-376-3
GHS signal word: Warning. Pictograms: Serious health hazard 201 suppliers listed Drug substance
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Fenofibrate chemical structure, C20H21ClO4, CAS 49562-28-9
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Crystals from isopropanol
Melting point
80 to 81
Solubility
Practically insoluble in water, slightly soluble in methanol, ethanol, soluble in aceton…
HS code
291899
Category
Cardiovascular and metabolic drugs
Illustrative photo, closed blue fibre drums on a pallet in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Fenofibrate?

Plain description, key identifiers and synonyms

Fenofibrate is a chlorobenzophenone that is (4-chlorophenyl)(phenyl)methanone substituted by a [2-methyl-1-oxo-1-(propan-2-yloxy)propan-2-yl]oxy group at position 1 on the phenyl ring. It has a role as a geroprotector, an antilipemic drug, a xenobiotic and an environmental contaminant. It is a chlorobenzophenone, an aromatic ether, an isopropyl ester and a member of monochlorobenzenes. It is functionally related to a benzophenone.

Fenofibrate is a drug of the fibrate class, mainly used to reduce cholesterol levels.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate
CAS number
49562-28-9 CAS number cross-checked
EC number
256-376-3
Molecular formula
C20H21ClO4
UNII
U202363UOS
MDL number
MFCD00133314
InChIKey
YMTINGFKWWXKFG-UHFFFAOYSA-N
InChI
InChI=1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3
SMILES (canonical and isomeric)
CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl

Synonyms

  • Procetofen
  • Tricor
  • Lipantil
  • Fenobrate
  • Lipanthyl
  • Lipidil
  • Lipoclar
  • Antara
  • Finofibrate
  • Fenogal
  • Lipofene
  • Liposit
  • Nolipax
  • Secalip
  • Triglide
  • Elasterin
  • Fenoglide
  • Fenotard
  • Protolipan
  • Ankebin
  • Lipofen
  • Lipsin
  • Fenofibrato
  • Fenofibratum
  • Procetofene
Show all 39 synonyms
  • propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate
  • Antara (micronized)
  • Supralip
  • Fenofibrate micronized
  • Tricor (micronized)
  • Fenofibrate (micronized)
  • Propanoic acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-, 1-methylethyl ester
  • 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester
  • Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate
  • Fenofibrate delayed release
  • Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate
  • Propanoic acid, 2-(4-(4-chlorobenzoyl)phenoxy)-2-methyl-, 1-methylethyl ester
  • Phenofibrate
  • Lofibra

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystals from isopropanolexp.
Melting point
80 to 81exp.
Solubility
Practically insoluble in water, slightly soluble in methanol, ethanol, soluble in acetone, ether, benzene, chloroformexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
360.84 g/molcalc.
Exact mass
360.1128 Dacalc.
LogP (octanol/water)
4.68calc.
Topological polar surface area
52.6 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
6calc.
Heavy atoms
25calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.3calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(c1ccccc1)c1ccccc1

O=C(c1ccccc1)c1ccccc1

2 rings, 14 atoms, the Benzophenone ring system.

5,108 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H373May cause damage to organs through prolonged or repeated exposure.
  • H413May cause long lasting harmful effects to aquatic life.
Precautionary statements (4)
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P273Avoid release to the environment.
  • P319Get medical help if you feel unwell.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Fenofibrate suppliers

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All 201 suppliers
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Where suppliers are based

201 suppliers in 23 countries

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Fenofibrate price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Adjunctive therapy to diet to reduce elevated LDL-C, Total-C, triglycerides and Apo B, and to increase HDL-C in adult patients with hypercholesterolemia or mixed dyslipidemia.

Therapeutic category: Antilipemic.

Use classes: Cardiovascular system.

Pharmacological actions

  • Hypolipidemic Agents

Roles

  • anti-HIV agent
  • anti-inflammatory agent
  • anti-obesity agent
  • antiatherosclerotic agent
  • anticholesteremic drug
  • antihypertensive agent
  • antilipemic drug
  • antimicrobial agent
  • antineoplastic agent
  • antiviral agent
  • cardiovascular drug
  • environmental contaminant
  • geroprotector
  • hypoglycemic agent
  • pharmaceutical
  • protective agent
  • xenobiotic

Pharmacology

Fenofibrate is a Peroxisome Proliferator Receptor alpha Agonist. The mechanism of action of fenofibrate is as a Peroxisome Proliferator-activated Receptor alpha Agonist.

How it is made

Fenofibrate is prepared from 4-chloro-4-hydroxybenzophenone either in analogy to the synthesis of clofibric acid and in the final step converted into the isopropyl ester or by alkylation with preformed isopropyl alpha-bromoisobutyrate.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Fenofibrate is traded under.

HS 2918.99Indicative HS code

Carboxylic acids, with additional oxygen function (not alcohol, phenol, aldehyde or ketone)…

World exports in 2024
$1.46B
−1.1% vs 2023, imports $1.54B
2019 to 2024
Top exporters
  1. China40.0%
  2. India * partner reported26.6%
  3. Germany8.0%
Top importers
  1. United States25.6%
  2. Brazil6.7%
  3. Argentina5.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Fenofibrate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Fenofibrate, based on the data on this page

What is Fenofibrate?

Fenofibrate is a chlorobenzophenone that is (4-chlorophenyl)(phenyl)methanone substituted by a [2-methyl-1-oxo-1-(propan-2-yloxy)propan-2-yl]oxy group at position 1 on the phenyl ring. It has a role as a geroprotector, an antilipemic drug, a xenobiotic and an environmental contaminant.

What is the CAS number of Fenofibrate?

The CAS registry number of Fenofibrate is 49562-28-9.

What is the molecular formula and weight of Fenofibrate?

The molecular formula of Fenofibrate is C20H21ClO4 and its molar mass is 360.84 g/mol.

What is Fenofibrate used for?

Adjunctive therapy to diet to reduce elevated LDL-C, Total-C, triglycerides and Apo B, and to increase HDL-C in adult patients with hypercholesterolemia or mixed dyslipidemia. Therapeutic category: Antilipemic. Use classes: Cardiovascular system.

Is Fenofibrate hazardous?

Fenofibrate carries the GHS signal word "Warning". Main hazards: may cause damage to organs through prolonged or repeated exposure, may cause long lasting harmful effects to aquatic life. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Fenofibrate?

Fenofibrate is usually classified under HS code 291899 (Carboxylic acids with additional oxygen function and their anhydrides, halides…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Fenofibrate?

CompoundList lists 201 suppliers of Fenofibrate in China, India, United States, Germany and 19 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Fenofibrate in India?

53 suppliers in India list Fenofibrate on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Fenofibrate?

Suppliers quote Fenofibrate on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Fenofibrate

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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