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Oncology and immunology drugs

Fleroxacin

Also known as Megalone, Megalocin, Fleroxicin

CAS 79660-72-3Formula C17H18F3N3O3Molar mass 369.34 g/molEC 677-525-2
GHS signal word: Warning. Pictograms: Serious health hazard 32 suppliers listed
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Fleroxacin chemical structure, C17H18F3N3O3, CAS 79660-72-3
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
79660-72-3
Formula
C17H18F3N3O3
Molar mass
369.34 g/mol
EC number
677-525-2
HS code
293359
Category
Oncology and immunology drugs

What is Fleroxacin?

Plain description, key identifiers and synonyms

Fleroxacin is a fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-negative bacteria. It has a role as an antibacterial drug, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor and a topoisomerase IV inhibitor. It is a monocarboxylic acid, a member of quinolines, a difluorobenzene, a N-alkylpiperazine and a fluoroquinolone antibiotic.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
CAS number
79660-72-3 CAS number cross-checkedOther or deprecated CAS: 79660-53-0
EC number
677-525-2
Molecular formula
C17H18F3N3O3
UNII
N804LDH51K
MDL number
MFCD00864880
InChIKey
XBJBPGROQZJDOJ-UHFFFAOYSA-N
InChI
InChI=1S/C17H18F3N3O3/c1-21-4-6-22(7-5-21)15-12(19)8-10-14(13(15)20)23(3-2-18)9-11(16(10)24)17(25)26/h8-9H,2-7H2,1H3,(H,25,26)
SMILES (canonical and isomeric)
CN1CCN(CC1)C2=C(C=C3C(=C2F)N(C=C(C3=O)C(=O)O)CCF)F

Synonyms

  • Megalone
  • Megalocin
  • Fleroxicin
  • Fleroxacino
  • Quinodis
  • Fleroxacine
  • Fleroxacinum
  • AM 833
  • FLRX
  • 6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
  • Ro 23-6240/000
  • Ro-23-6240/000
  • 3-Quinolinecarboxylic acid, 6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-
  • Ro 236240
  • Ro 23 6240
  • 6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
  • Ro 23-6240
  • 6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
  • Fleroxacin (Quinodis)
  • 6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid
  • RO 23-6240, AM-833
  • Megalosin
  • Megalocin (TN)
  • Megalone (TN)
  • Fleroxacin (JAN/USAN/INN)
Show all 26 synonyms
  • 6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methylpiperazino)-4-oxo-3-quinolinecarboxylic acid

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
369.34 g/molcalc.
Exact mass
369.13 Dacalc.
LogP (octanol/water)
1.7calc.
Topological polar surface area
65.78 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
4calc.
Heavy atoms
26calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.41calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=c1cc[nH]c2cc(N3CCNCC3)ccc12

O=c1cc[nH]c2cc(N3CCNCC3)ccc12

3 rings, 17 atoms.

110 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H371May cause damage to organs.
Precautionary statements (6)
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P308 + P316If exposed or concerned: Get emergency medical help immediately.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Fleroxacin suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 32 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

32 suppliers in 7 countries

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Fleroxacin price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Anti-Infective Agents
  • Topoisomerase II Inhibitors

Roles

  • antibacterial agent
  • antibacterial drug
  • antiinfective agent
  • antimicrobial agent
  • antimicrobial drug
  • enzyme inhibitor
  • pharmaceutical
  • topoisomerase IV inhibitor
  • topoisomerase inhibitor

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Fleroxacin is traded under.

HS 2933.59Indicative HS code

Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring, other

World exports in 2024
$18.4B
+10.5% vs 2023, imports $24.8B
2019 to 2024
Top exporters
  1. Ireland43.6%
  2. Switzerland * partner reported26.3%
  3. China7.9%
Top importers
  1. Slovenia30.3%
  2. United States30.1%
  3. Germany15.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Fleroxacin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Fleroxacin, based on the data on this page

What is Fleroxacin?

Fleroxacin is a fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-negative bacteria.

What is the CAS number of Fleroxacin?

The CAS registry number of Fleroxacin is 79660-72-3. Other or deprecated CAS numbers: 79660-53-0.

What is the molecular formula and weight of Fleroxacin?

The molecular formula of Fleroxacin is C17H18F3N3O3 and its molar mass is 369.34 g/mol.

What is Fleroxacin used for?

Use classes: Pharmaceuticals.

Is Fleroxacin hazardous?

Fleroxacin carries the GHS signal word "Warning". Main hazards: may cause damage to organs. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Fleroxacin?

Fleroxacin is usually classified under HS code 293359 (Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Fleroxacin?

CompoundList lists 32 suppliers of Fleroxacin in United States, China, Germany, France and 3 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Fleroxacin?

Suppliers quote Fleroxacin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Fleroxacin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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