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Impurities and reference standards

Formoterol

Also known as Oxis, Formoterolum, N-[2-hydroxy-5-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]phenyl]formamide

CAS 73573-87-2Formula C19H24N2O4Molar mass 344.41 g/molEC 615-991-0
GHS signal word: Danger. Pictograms: Harmful or irritant, Serious health hazard 49 suppliers listed Drug substance
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Formoterol chemical structure, C19H24N2O4, CAS 73573-87-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
73573-87-2
Formula
C19H24N2O4
Molar mass
344.41 g/mol
Solubility
In water, 1.12 × 10⁺⁴ mg/L at 25 °C /Estimated/
HS code
292429
Category
Impurities and reference standards

What is Formoterol?

Plain description, key identifiers and synonyms

N-[2-hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide is a phenylethanoloamine having 4-hydroxy and 3-formamido substituents on the phenyl ring and an N-(4-methoxyphenyl)propan-2-yl substituent. It is a member of formamides, a member of phenylethanolamines, a member of phenols, a secondary alcohol and a secondary amino compound.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-[2-hydroxy-5-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]phenyl]formamide
CAS number
73573-87-2 CAS number cross-checkedOther or deprecated CAS: 126587-85-7, 128954-45-0
EC numbers
615-991-0, 936-018-9
Molecular formula
C19H24N2O4
InChIKey
BPZSYCZIITTYBL-UHFFFAOYSA-N
InChI
InChI=1S/C19H24N2O4/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22)
SMILES (canonical and isomeric)
CC(CC1=CC=C(C=C1)OC)NCC(C2=CC(=C(C=C2)O)NC=O)O

Synonyms

  • Oxis
  • Formoterolum
  • N-[2-hydroxy-5-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]phenyl]formamide
  • (+-)-Formoterol
  • 2'-hydroxy-5'-(1-hydroxy-2-((p-methoxy-alpha-methylphenethyl)amino)ethyl)formanilide
  • 2'-hydroxy-5'-{1-hydroxy-2-[(p-methoxy-alpha-methylphenethyl)amino]ethyl}formanilide
  • N-(2-hydroxy-5-(1-hydroxy-2-(1-(4-methoxyphenyl)propan-2-ylamino)ethyl)phenyl)formamide
  • (+-)-2'-Hydroxy-5'-((RS)-1-hydroxy-2-(((RS)-p-methoxy-alpha-methylphenethyl)amino)ethyl)formanilide
  • Eformoterol
  • n-[2-hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide
  • Formoterol (INN)
  • Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, [R-(R*,S*)]-
  • N-[2-hydroxy-5-(1-hydroxy-2-{[2-(4-methoxyphenyl)-1-methylethyl]amino}ethyl)phenyl]formamide
  • Oxis (TN)
  • Oxeze/Oxis
  • N-(2-Hydroxy-5-(1-hydroxy-2-((1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)phenyl)formamide
  • n-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide
  • Formoterol Impurity 109
  • N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methyl-ethyl]amino]ethyl]phenyl]formamide
  • N-[2-hydroxy-5-[(1rs)-1-hydroxy-2-[[(1rs)-2(4methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl] formamide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Solubility
In water, 1.12 × 10⁺⁴ mg/L at 25 °C /Estimated/exp.
Vapour pressure
5.0 × 10⁻¹⁴ mm Hg at 25 °C /Estimated/exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
344.41 g/molcalc.
Exact mass
344.1736 Dacalc.
LogP (octanol/water)
2.22calc.
Topological polar surface area
90.82 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
9calc.
Heavy atoms
25calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.32calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(CCNCCc2ccccc2)cc1

c1ccc(CCNCCc2ccccc2)cc1

2 rings, 17 atoms, the 2-Phenyl-N-(2-phenylethyl)ethan-1-amine ring system.

271 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H332Harmful if inhaled.
  • H361Suspected of damaging fertility or the unborn child.
  • H362May cause harm to breast-fed children.
  • H370Causes damage to organs.
  • H372Causes damage to organs through prolonged or repeated exposure.
  • H412Harmful to aquatic life with long lasting effects.
Precautionary statements (17)
  • P203Obtain, read and follow all safety instructions before use.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P263Avoid contact during pregnancy and while nursing.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P308 + P316If exposed or concerned: Get emergency medical help immediately.
  • P317Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Formoterol suppliers

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All 49 suppliers
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Where suppliers are based

49 suppliers in 10 countries

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Formoterol price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Medication: antiasthmatic.

Roles

  • adrenergic agent
  • adrenergic agonist
  • anti-asthmatic agent
  • anti-asthmatic drug
  • antimicrobial agent
  • antiviral agent
  • beta-adrenergic agonist
  • beta-adrenergic drug
  • bronchodilator agent
  • neurotransmitter agent
  • pharmaceutical

Pharmacology

Formoterol is a beta2-Adrenergic Agonist. The mechanism of action of formoterol is as an Adrenergic beta2-Agonist.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Formoterol is traded under.

HS 2924.29Indicative HS code

Cyclic amides (including cyclic carbamates) and their derivatives, salts thereof, other

World exports in 2024
$5.69B
−5.1% vs 2023, imports $5.8B
2019 to 2024
Top exporters
  1. China32.3%
  2. Switzerland * partner reported13.6%
  3. Norway * partner reported12.8%
Top importers
  1. United States15.9%
  2. Ireland15.8%
  3. Germany11.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Formoterol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Formoterol, based on the data on this page

What is Formoterol?

N-[2-hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide is a phenylethanoloamine having 4-hydroxy and 3-formamido substituents on the phenyl ring and an N-(4-methoxyphenyl)propan-2-yl substituent.

What is the CAS number of Formoterol?

The CAS registry number of Formoterol is 73573-87-2. Other or deprecated CAS numbers: 126587-85-7, 128954-45-0.

What is the molecular formula and weight of Formoterol?

The molecular formula of Formoterol is C19H24N2O4 and its molar mass is 344.41 g/mol.

What is Formoterol used for?

Medication: antiasthmatic.

Is Formoterol hazardous?

Formoterol carries the GHS signal word "Danger". Main hazards: harmful if inhaled, suspected of damaging fertility or the unborn child, may cause harm to breast-fed children. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Formoterol?

Formoterol is usually classified under HS code 292429 (Cyclic amides (including cyclic carbamates) and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Formoterol?

CompoundList lists 49 suppliers of Formoterol in China, United States, Germany, Spain and 6 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Formoterol?

Suppliers quote Formoterol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Formoterol

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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