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Skin conditioning agents and actives

Gallium maltolate

Also known as tris(maltolato)gallium(III), tris(3-hydroxy-2-methyl-4H-pyran-4-onato)gallium(III), 4H-pyran-4-one, 3-hydroxy-2-methyl-, gallium salt (3:1)

CAS 108560-70-9Formula C18H15GaO9Molar mass 445.03 g/mol
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Gallium maltolate chemical structure, C18H15GaO9, CAS 108560-70-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
108560-70-9
Formula
C18H15GaO9
Molar mass
445.03 g/mol
HS code
293299
Category
Skin conditioning agents and actives

What is Gallium maltolate?

Plain description, key identifiers and synonyms

Gallium Maltolate is an orally bioavailable form of the element gallium (Ga) composed of a trivalent gallium cation (Ga3+) coordinated to three maltolate ligands, with anti-inflammatory, anti-proliferative, antineoplastic, analgesic, antiresorptive and antibacterial activities. Upon administration of gallium maltolate, Ga3+, which is structurally similar to the ferric ion (Fe3+), competes with and replaces Fe3+ in many vital Fe 3+-mediated biological reactions.. Unlike Fe3+, Ga3+ cannot be reduced, cannot participate in redox reactions and cannot mimic Fe3+ functions. In rapidly proliferating cells, such as cancer cells, high amounts of iron are needed for DNA synthesis.

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The incorporation of Ga3+ inactivates the Fe3+-dependent enzyme ribonucleotide reductase (RR), an enzyme essential for DNA synthesis, leading to an inhibition of DNA synthesis and induction of cell death in rapidly proliferating cells. Gallium similarly reduces bacterial cell growth. In addition, Ga3+ is able to suppress inflammation through the down-regulation of pro-inflammatory cells and the inhibition of pro-inflammatory cytokine secretion. Gallium also exerts analgesic effects due to the inhibition of Fe3+-dependent enzymes involved in inflammation and may interfere with the activity of certain metalloproteinases and neuropeptides that are implicated in pain. Also, gallium is able to inhibit bone resorption by osteoclasts, may inhibit metastasis to bone and may prevent the destruction of bone by tumors.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
gallium tris(2-methyl-4-oxopyran-3-olate)
CAS number
108560-70-9
Molecular formula
C18H15GaO9
UNII
17LEI49C2G
MDL number
MFCD27976780
INCI name
GALLIUM MALTOLATE
InChIKey
ASYYOZSDALANRF-UHFFFAOYSA-K
InChI
InChI=1S/3C6H6O3.Ga/c3*1-4-6(8)5(7)2-3-9-4;/h3*2-3,8H,1H3;/q;;;+3/p-3
SMILES (canonical and isomeric)
CC1=C(C(=O)C=CO1)[O-].CC1=C(C(=O)C=CO1)[O-].CC1=C(C(=O)C=CO1)[O-].[Ga+3]

Synonyms

  • tris(maltolato)gallium(III)
  • tris(3-hydroxy-2-methyl-4H-pyran-4-onato)gallium(III)
  • 4H-pyran-4-one, 3-hydroxy-2-methyl-, gallium salt (3:1)
  • gallium tris(2-methyl-4-oxo-4H-pyran-3-olate)
  • gallium, 2-methyl-4-oxopyran-3-olate
  • C18H15GaO9
  • gallium, 2-methyl-4-oxidanylidene-pyran-3-olate
  • 3-bis[(2-methyl-4-oxopyran-3-yl)oxy]gallanyloxy-2-methylpyran-4-one
  • Gallium, tris(3-(hydroxy-.kappa.o)-2-methyl-4H-pyran-4-onato-.kappa.o4)-, (oc-6-21)-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
445.03 g/molcalc.
Exact mass
443.9972 Dacalc.
LogP (octanol/water)
-0.32calc.
Topological polar surface area
159.8 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
9calc.
Rotatable bonds
0calc.
Heavy atoms
28calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.17calc.
Formal charge
0calc.
Stereocentres
0calc.
Components
4calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=c1ccocc1

O=c1ccocc1

1 ring, 7 atoms, the 4H-Pyran-4-one ring system.

339 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Gallium maltolate suppliers

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Where suppliers are based

1 supplier in 1 country

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Gallium maltolate price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name GALLIUM MALTOLATE(skin conditioning)

Cosmetic functions

  • Skin conditioning

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Gallium maltolate is traded under.

HS 2932.99Indicative HS code

Heterocyclic compounds with oxygen hetero-atom(s) only, other

World exports in 2024
$3.81B
+10.3% vs 2023, imports $7.05B
2019 to 2024
Top exporters
  1. China28.9%
  2. Switzerland * partner reported12.7%
  3. Germany7.8%
Top importers
  1. United States49.7%
  2. China11.9%
  3. India * partner reported3.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Gallium maltolate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Gallium maltolate, based on the data on this page

What is Gallium maltolate?

Gallium Maltolate is an orally bioavailable form of the element gallium (Ga) composed of a trivalent gallium cation (Ga3+) coordinated to three maltolate ligands, with anti-inflammatory, anti-proliferative, antineoplastic, analgesic, antiresorptive and antibacterial activities.

What is the CAS number of Gallium maltolate?

The CAS registry number of Gallium maltolate is 108560-70-9.

What is the molecular formula and weight of Gallium maltolate?

The molecular formula of Gallium maltolate is C18H15GaO9 and its molar mass is 445.03 g/mol.

What is Gallium maltolate used for?

Known uses and roles of Gallium maltolate include skin conditioning agents in cosmetics and personal care and skin conditioning.

Is Gallium maltolate hazardous?

No GHS hazard classification for Gallium maltolate is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Gallium maltolate?

Gallium maltolate is usually classified under HS code 293299 (Heterocyclic compounds with oxygen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Gallium maltolate?

CompoundList lists 1 supplier of Gallium maltolate in China. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Gallium maltolate?

Suppliers quote Gallium maltolate on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Gallium maltolate

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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