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Cardiovascular and metabolic drugs

Gemfibrozil

Also known as 5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic acid, Lopid, Lipur

CAS 25812-30-0Formula C15H22O3Molar mass 250.34 g/molEC 247-280-2
GHS signal word: Warning. Pictograms: Harmful or irritant, Serious health hazard, Hazardous to the environment 101 suppliers listed Drug substance
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Gemfibrozil chemical structure, C15H22O3, CAS 25812-30-0
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Crystals from hexane
Melting point
62 °C
Boiling point
159 °C
HS code
291899
Category
Cardiovascular and metabolic drugs
Illustrative photo, drums, an IBC tote and sacks in a chemical warehouse in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Gemfibrozil?

Plain description, key identifiers and synonyms

Gemfibrozil is an aromatic ether. It has a role as an antilipemic drug. It is functionally related to a valeric acid.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid
CAS number
25812-30-0 CAS number cross-checkedOther or deprecated CAS: 114413-98-8
EC numbers
247-280-2, 657-339-8
Molecular formula
C15H22O3
UNII
Q8X02027X3
MDL number
MFCD00079335
InChIKey
HEMJJKBWTPKOJG-UHFFFAOYSA-N
InChI
InChI=1S/C15H22O3/c1-11-6-7-12(2)13(10-11)18-9-5-8-15(3,4)14(16)17/h6-7,10H,5,8-9H2,1-4H3,(H,16,17)
SMILES (canonical and isomeric)
CC1=CC(=C(C=C1)C)OCCCC(C)(C)C(=O)O

Synonyms

  • 5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic acid
  • Lopid
  • Lipur
  • Jezil
  • Gemfibrozilum
  • Gemfibrozilo
  • Gemlipid
  • Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl-
  • 2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid
  • Gen-Fibro
  • 2,2-Dimethyl-5-(2,5-xylyloxy)valeriansaeure
  • CI 719
  • 2,2-Dimethyl-5-(2,5-dimethylphenoxy)valeriansaeure
  • Valeric acid, 2,2-dimethyl-5-(2,5-xylyloxy)-
  • Gemfibrosil
  • Lopid R
  • ApoGemfibrozil
  • GenGemfibrozil
  • Genlip
  • NuGemfibrozil
  • Apo Gemfibrozil
  • Gen Gemfibrozil
  • Nu Gemfibrozil
  • Novo Gemfibrozil
  • PMS Gemfibrozil
Show all 37 synonyms
  • Gemfibrozil, SBPA
  • Gemfibrozil, GenRX
  • Bayvit, Gemfibrozilo
  • Gemfibrozil, Healthsense
  • Emfib
  • Decrelip
  • Lanaterom
  • Micolip
  • Regulip
  • Sinelip
  • WL-Gemfibrozil
  • Innogem

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystals from hexaneexp.
Melting point
62 °Cexp.
Boiling point
159 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
250.34 g/molcalc.
Exact mass
250.1569 Dacalc.
LogP (octanol/water)
3.57calc.
Topological polar surface area
46.53 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
6calc.
Heavy atoms
18calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.53calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H302Harmful if swallowed.
  • H351Suspected of causing cancer.
  • H361Suspected of damaging fertility or the unborn child.
  • H411Toxic to aquatic life with long lasting effects.
Precautionary statements (11)
  • P203Obtain, read and follow all safety instructions before use.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P330Rinse mouth.
  • P391Collect spillage.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Gemfibrozil suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 101 suppliers
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Where suppliers are based

101 suppliers in 17 countries

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Gemfibrozil price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Medication: Lipid regulator.

Therapeutic category: Antilipemic.

Pharmacological actions

  • Cytochrome P-450 CYP2C8 Inhibitors
  • Hypolipidemic Agents

Roles

  • analgesic
  • anti-HIV agent
  • anti-anaemic agent
  • antidyskinesia agent
  • antilipemic drug
  • antimicrobial agent
  • antineoplastic agent
  • antiparkinson drug
  • antiviral agent
  • cardiovascular drug
  • hypoglycemic agent
  • immunomodulator
  • immunosuppressive agent
  • pharmaceutical

Functional uses

  • Pharmaceutical

Pharmacology

Gemfibrozil is a Peroxisome Proliferator Receptor alpha Agonist. The mechanism of action of gemfibrozil is as a Peroxisome Proliferator-activated Receptor alpha Agonist.

How it is made

It is prepared by reaction of the lithium salt of sodium or magnesium isobutyrate (made by reaction of the absolutely dry isobutyrates with butyllithium) with 3-(2,5-xylyloxy)propyl bromide.

Preparation: M. Hayashi et al., De 2700021, eidem, US 4052512 (both 1977 to Ono).

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Gemfibrozil is traded under.

HS 2918.99Indicative HS code

Carboxylic acids, with additional oxygen function (not alcohol, phenol, aldehyde or ketone)…

World exports in 2024
$1.46B
−1.1% vs 2023, imports $1.54B
2019 to 2024
Top exporters
  1. China40.0%
  2. India * partner reported26.6%
  3. Germany8.0%
Top importers
  1. United States25.6%
  2. Brazil6.7%
  3. Argentina5.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Gemfibrozil is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Gemfibrozil, based on the data on this page

What is Gemfibrozil?

Gemfibrozil is an aromatic ether. It has a role as an antilipemic drug. It is functionally related to a valeric acid.

What is the CAS number of Gemfibrozil?

The CAS registry number of Gemfibrozil is 25812-30-0. Other or deprecated CAS numbers: 114413-98-8.

What is the molecular formula and weight of Gemfibrozil?

The molecular formula of Gemfibrozil is C15H22O3 and its molar mass is 250.34 g/mol.

What is Gemfibrozil used for?

Medication: Lipid regulator. Therapeutic category: Antilipemic.

Is Gemfibrozil hazardous?

Gemfibrozil carries the GHS signal word "Warning". Main hazards: harmful if swallowed, suspected of causing cancer, suspected of damaging fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Gemfibrozil?

Gemfibrozil is usually classified under HS code 291899 (Carboxylic acids with additional oxygen function and their anhydrides, halides…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Gemfibrozil?

CompoundList lists 101 suppliers of Gemfibrozil in United States, China, United Kingdom, India and 13 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Gemfibrozil in India?

5 suppliers in India list Gemfibrozil on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Gemfibrozil?

Suppliers quote Gemfibrozil on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Gemfibrozil

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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