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Cardiovascular and metabolic drugs

Glipizide

Also known as Glucotrol, Glydiazinamide, Glibenese

CAS 29094-61-9Formula C21H27N5O4SMolar mass 445.55 g/molEC 249-427-6
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Glipizide chemical structure, C21H27N5O4S, CAS 29094-61-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
29094-61-9
Formula
C21H27N5O4S
Molar mass
445.55 g/mol
EC number
249-427-6
HS code
293590
Category
Cardiovascular and metabolic drugs

What is Glipizide?

Plain description, key identifiers and synonyms

Glipizide is an N-sulfonylurea that is glyburide in which the (5-chloro-2-methoxybenzoyl group is replaced by a (5-methylpyrazin-2-yl)carbonyl group. An oral hypoglycemic agent, it is used in the treatment of type 2 diabetes mellitus. It has a role as a hypoglycemic agent, an EC 2.7.1.33 (pantothenate kinase) inhibitor and an insulin secretagogue. It is a monocarboxylic acid amide, a member of pyrazines, an aromatic amide and a N-sulfonylurea.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-5-methylpyrazine-2-carboxamide
CAS number
29094-61-9 CAS number cross-checkedOther or deprecated CAS: 172964-66-8
EC number
249-427-6
Molecular formula
C21H27N5O4S
UNII
X7WDT95N5C
MDL number
MFCD00072159
InChIKey
ZJJXGWJIGJFDTL-UHFFFAOYSA-N
InChI
InChI=1S/C21H27N5O4S/c1-15-13-24-19(14-23-15)20(27)22-12-11-16-7-9-18(10-8-16)31(29,30)26-21(28)25-17-5-3-2-4-6-17/h7-10,13-14,17H,2-6,11-12H2,1H3,(H,22,27)(H2,25,26,28)
SMILES (canonical and isomeric)
CC1=CN=C(C=N1)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3

Synonyms

  • Glucotrol
  • Glydiazinamide
  • Glibenese
  • Melizide
  • Minidiab
  • Minodiab
  • Dipazide
  • Glucozide
  • Glupitel
  • Glupizide
  • Napizide
  • Sucrazide
  • Mindiab
  • Ozidia
  • Glibetin
  • Glidiab
  • Glucolip
  • Minidab
  • Aldiab
  • Digrin
  • Glican
  • Glipid
  • Glyde
  • Gluco-Rite
  • Glucotrol XL
Show all 39 synonyms
  • Glipizida
  • Glipizidum
  • CP 28720
  • CP 28,720
  • Glipizide slow release
  • CP-28,720
  • 1-Cyclohexyl-3-((p-(2-(5-methylpyrazinecarboxamido)ethyl)phenyl)sulfonyl)urea
  • Glidiazinamide
  • Glypidizine
  • Pyrazinecarboxamide, N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-5-methyl-
  • 1-cyclohexyl-3-[[p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl]sulfonyl]urea
  • N-(4-(beta-(5-Methylpyrazine-2-carboxamido)ethyl)benzenesulphonyl)-N'-cyclohexylurea
  • N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-5-methylpyrazine-2-carboxamide
  • Urea, 1-cyclohexyl-3-((p-(2-(5-methylpyrazinecarboxamido)ethyl)phenyl)sulfonyl)-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
445.55 g/molcalc.
Exact mass
445.1784 Dacalc.
LogP (octanol/water)
2.08calc.
Topological polar surface area
130.2 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
7calc.
Heavy atoms
31calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.43calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(NC1CCCCC1)NS(=O)(=O)c1ccc(CCNC(=O)c2cnccn2)cc1

O=C(NC1CCCCC1)NS(=O)(=O)c1ccc(CCNC(=O)c2cnccn2)cc1

3 rings, 30 atoms.

9 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Glipizide suppliers

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All 154 suppliers
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Where suppliers are based

154 suppliers in 19 countries

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Glipizide price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Industries and functions

Pharmacological actions

  • Hypoglycemic Agents

Roles

  • antiatherosclerotic agent
  • antineoplastic agent
  • cardiovascular drug
  • enzyme inhibitor
  • hypoglycemic agent
  • insulin secretagogue
  • pharmaceutical
  • secretagogue

Pharmacology

Glipizide is a Sulfonylurea.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Glipizide is traded under.

HS 2935.90Indicative HS code

Sulphonamides, other

World exports in 2024
$5.64B
−11.0% vs 2023, imports $8.56B
2019 to 2024
Top exporters
  1. Ireland43.1%
  2. China12.0%
  3. India * partner reported9.5%
Top importers
  1. United States23.6%
  2. Slovenia19.1%
  3. Spain11.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Glipizide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Glipizide, based on the data on this page

What is Glipizide?

Glipizide is an N-sulfonylurea that is glyburide in which the (5-chloro-2-methoxybenzoyl group is replaced by a (5-methylpyrazin-2-yl)carbonyl group. An oral hypoglycemic agent, it is used in the treatment of type 2 diabetes mellitus.

What is the CAS number of Glipizide?

The CAS registry number of Glipizide is 29094-61-9. Other or deprecated CAS numbers: 172964-66-8.

What is the molecular formula and weight of Glipizide?

The molecular formula of Glipizide is C21H27N5O4S and its molar mass is 445.55 g/mol.

What is Glipizide used for?

Known uses and roles of Glipizide include antidiabetics in pharmaceuticals, antiatherosclerotic agent, antineoplastic agent, cardiovascular drug, enzyme inhibitor and 5 more.

Is Glipizide hazardous?

No GHS hazard classification for Glipizide is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Glipizide?

Glipizide is usually classified under HS code 293590 (Sulphonamides, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Glipizide?

CompoundList lists 154 suppliers of Glipizide in United States, China, India, Germany and 15 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Glipizide in India?

30 suppliers in India list Glipizide on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Glipizide?

Suppliers quote Glipizide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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