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Impurities and reference standards

Guanidine

Also known as Iminourea, Carbamidine, Aminomethanamidine

CAS 113-00-8Formula CH5N3Molar mass 59.07 g/molEC 204-021-8
GHS signal word: Danger. Pictograms: Flammable, Corrosive, Acute toxicity (severe), Harmful or irritant 45 suppliers listed
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Guanidine chemical structure, CH5N3, CAS 113-00-8
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Deliquescent crystalline mass
Melting point
50 °C
Solubility
In water, 1,840 mg/L at 25 °C
HS code
292529
Category
Impurities and reference standards
Illustrative photo, closed blue fibre drums on a pallet in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Guanidine?

Plain description, key identifiers and synonyms

Guanidine is an aminocarboxamidine, the parent compound of the guanidines. It is a member of guanidines, a carboxamidine and a one-carbon compound. It is a conjugate base of a guanidinium.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
guanidine
CAS number
113-00-8 CAS number cross-checkedOther or deprecated CAS: 50-01-1
EC number
204-021-8
Molecular formula
CH5N3
UNII
JU58VJ6Y3B
InChIKey
ZRALSGWEFCBTJO-UHFFFAOYSA-N
InChI
InChI=1S/CH5N3/c2-1(3)4/h(H5,2,3,4)
SMILES (canonical and isomeric)
C(=N)(N)N

Synonyms

  • Iminourea
  • Carbamidine
  • Aminomethanamidine
  • Carbamamidine
  • Imidourea
  • Aminoformamidine
  • Guanidin
  • H2N-C(=NH)-NH2
  • Phosphate, Guanidine
  • Monohydrate, Guanidine
  • Monohydroiodine, Guanidine
  • Guanidine, free base
  • Guanidine, Hydrochloride
  • GAI
  • Gu
  • Ribavirin Impurity T
  • 4-03-00-00148 (Beilstein Handbook Reference)
  • (NH2)2C=NH

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Deliquescent crystalline massexp.
Melting point
50 °Cexp.
Solubility
In water, 1,840 mg/L at 25 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
59.07 g/molcalc.
Exact mass
59.0483 Dacalc.
LogP (octanol/water)
-1.16calc.
Topological polar surface area
75.89 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
0calc.
Heavy atoms
4calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS02: Flammable
Flammable
GHS05: Corrosive
Corrosive
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H225Highly flammable liquid and vapour.
  • H301Toxic if swallowed.
  • H302 + H332Harmful if swallowed. Harmful if inhaled.
  • H302Harmful if swallowed.
  • H311Toxic in contact with skin.
  • H314Causes severe skin burns and eye damage.
  • H315Causes skin irritation.
  • H318Causes serious eye damage.
  • H319Causes serious eye irritation.
  • H331Toxic if inhaled.
  • H332Harmful if inhaled.
  • H370Causes damage to organs.
Precautionary statements (38)
  • P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P233Keep container tightly closed.
  • P240Ground and bond container and receiving equipment.
  • P241Use explosion-proof electrical, ventilating and lighting equipment.
  • P242Use non-sparking tools.
  • P243Take action to prevent static discharges.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P262Do not get in eyes, on skin, or on clothing.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P301 + P317If swallowed: Get medical help.
  • P301 + P330 + P331If swallowed: Rinse mouth. Do not induce vomiting.
  • P302 + P352If on skin: Wash with plenty of water.
  • P302 + P361 + P354If on skin: Take off immediately all contaminated clothing. Immediately rinse with water for several minutes.
  • P303 + P361 + P353If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P308 + P316If exposed or concerned: Get emergency medical help immediately.
  • P316Get emergency medical help immediately.
  • P317Get medical help.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P363Wash contaminated clothing before reuse.
  • P370 + P378In case of fire: Use appropriate media to extinguish.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P403 + P235Store in a well-ventilated place. Keep cool.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Guanidine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 45 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

45 suppliers in 10 countries

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Guanidine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Organic synthesis.

Starting material for munitions, polymeric resins, flame retardants, and pharmaceuticals.

Use classes: Pesticide transformation products.

Roles

  • antineoplastic agent
  • pharmaceutical

Pharmacology

Guanidine is an Acetylcholine Releasing Agent. The physiologic effect of guanidine is by means of Increased Acetylcholine Activity.

How it is made

From ammonium thiocyanate or thiourea + ammonia

(1) By heating calcium cyanamide with ammonium iodide. (2) By treating urea with ammonia under pressure.

Free guanidine can be isolated from guanidine salts by reaction with a strong base such as an alkali metal hydroxide or methoxide. After removal of the precipitated salt the free guanidine base is obtained as colorless, waxy, very hygroscopic crystals.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Guanidine is traded under.

HS 2925.29Indicative HS code

Imines and their derivatives, salts thereof, other

World exports in 2024
$1.8B
+12.4% vs 2023, imports $1.84B
2019 to 2024
Top exporters
  1. China35.9%
  2. France * partner reported15.5%
  3. Germany9.1%
Top importers
  1. United States13.3%
  2. China13.0%
  3. Brazil9.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Guanidine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Guanidine, based on the data on this page

What is Guanidine?

Guanidine is an aminocarboxamidine, the parent compound of the guanidines. It is a member of guanidines, a carboxamidine and a one-carbon compound. It is a conjugate base of a guanidinium.

What is the CAS number of Guanidine?

The CAS registry number of Guanidine is 113-00-8. Other or deprecated CAS numbers: 50-01-1.

What is the molecular formula and weight of Guanidine?

The molecular formula of Guanidine is CH5N3 and its molar mass is 59.07 g/mol.

What is Guanidine used for?

Organic synthesis. Starting material for munitions, polymeric resins, flame retardants, and pharmaceuticals. Use classes: Pesticide transformation products.

Is Guanidine hazardous?

Guanidine carries the GHS signal word "Danger". Main hazards: highly flammable liquid and vapour, toxic if swallowed, harmful if swallowed. harmful if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Guanidine?

Guanidine is usually classified under HS code 292529 (Imines and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Guanidine?

CompoundList lists 45 suppliers of Guanidine in China, United States, United Kingdom, Spain and 6 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Guanidine?

Suppliers quote Guanidine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Guanidine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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