CompoundList

Guanine

Also known as 2-Amino-6-hydroxypurine, 2-Aminohypoxanthine, Guanin

Guanine chemical structure, C5H5N5O, CAS 73-40-5
2D chemical structure

Key facts

What buyers check first

Appearance
Several desmotropic forms, usually amorphous
Melting point
360 °C
Boiling point
SUBLIMES
Solubility
CRYSTALLINE POWDER, LOSES WATER @ 100 °C & HYDROGEN CHLORIDE @ 200 °C, PRACTICALLY INSOL…
HS code
293359
Category
Dyes and pigments
Illustrative photo, 25 kg white woven sacks of powder on a pallet in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Guanine?

Plain description, key identifiers and synonyms

Guanine is a 2-aminopurine carrying a 6-oxo substituent. It has a role as a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a human metabolite and an algal metabolite. It is a member of 2-aminopurines, an oxopurine and a purine nucleobase. It derives from a hydride of a 9H-purine.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-amino-1,7-dihydropurin-6-one
CAS number
73-40-5 CAS number cross-checkedOther or deprecated CAS: 66224-64-4, 71660-36-1
EC number
200-799-8
Molecular formula
C5H5N5O
UNII
5Z93L87A1R
MDL number
MFCD00071533
INCI name
CI 75170, GUANINE
InChIKey
UYTPUPDQBNUYGX-UHFFFAOYSA-N
InChI
InChI=1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)
SMILES (canonical and isomeric)
C1=NC2=C(N1)C(=O)NC(=N2)N

Synonyms

  • 2-Amino-6-hydroxypurine
  • 2-Aminohypoxanthine
  • Guanin
  • Mearlmaid
  • Guanine enol
  • Pearl essence
  • Stella Polaris
  • Dew Pearl
  • Naturon
  • Natural white 1
  • Natural pearl essence
  • 6H-Purin-6-one, 2-amino-1,7-dihydro-
  • 2-Amino-1,7-dihydro-6H-purin-6-one
  • CI Natural white 1
  • C.I. Natural White 1
  • Hypoxanthine, 2-amino-
  • 6-Hydroxy-2-aminopurine
  • 2-amino-1,7-dihydropurin-6-one
  • CI 75170
  • 2-amino-3,7-dihydropurin-6-one
  • C.I. 75170
  • C.i. no. 75170 (guanine)
  • 2-amino-6,9-dihydro-1H-purin-6-one
  • 2-amino-6,7-dihydro-3H-purin-6-one
  • 2-amino-1H-purin-6(7H)-one
Show all 36 synonyms
  • 2-Amino-6-purinol
  • 2-amino-1,9-dihydro-6H-purin-6-one
  • 2-amino-9H-purin-6-ol
  • 6H-Purin-6-one, 2-amino-1,9-dihydro-
  • Mearlmaid AA
  • Guanine, 98%
  • 2-amino-1,9-dihydropurin-6-one
  • 2-Amino-6-hydroxy-1H-purine
  • 2-amino-1h-purin-6(9h)-one
  • 2-Amino-1,9-dihydro-purin-6-one
  • 2-aminohydropurin-6-one

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Several desmotropic forms, usually amorphousexp.
Melting point
360 °Cexp.
Boiling point
SUBLIMESexp.
Solubility
CRYSTALLINE POWDER, LOSES WATER @ 100 °C & HYDROGEN CHLORIDE @ 200 °C, PRACTICALLY INSOL IN WATER, ALC, ETHER, SOL IN ACIDULATED WATER /HYDROCHLORIDE/exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
151.13 g/molcalc.
Exact mass
151.0494 Dacalc.
LogP (octanol/water)
-0.77calc.
Topological polar surface area
100.5 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
0calc.
Heavy atoms
11calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=c1[nH]cnc2nc[nH]c12

O=c1[nH]cnc2nc[nH]c12

2 rings, 10 atoms, the Hypoxanthine ring system.

586 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Guanine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 123 suppliers
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Where suppliers are based

123 suppliers in 16 countries

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Guanine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Biochemical research, cosmetics.

Color additive.

Use classes: Cosmetics.

Cosmetic ingredient, INCI name CI 75170(colorant)

Roles

  • Escherichia coli metabolite
  • Saccharomyces cerevisiae metabolite
  • algal metabolite
  • animal metabolite
  • antineoplastic agent
  • bacterial metabolite
  • eukaryotic metabolite
  • fungal metabolite
  • human metabolite
  • mammalian metabolite
  • metabolite
  • mouse metabolite
  • pharmaceutical
  • prokaryotic metabolite

Functional uses

  • Dye
  • Opacifer

Cosmetic functions

  • Colorant
  • Opacifying

Pharmacology

Guanine is a purine base that is a constituent of nucleotides occurring in nucleic acids.

How it is made

Fisher, ber 30, 2226 (1897), traube, ber 33, 1371 (1900). German patents 134,984 (1903), 158,591 (1903), 162,336 (1904). Preparation of (15)n-isotopic guanine following traube's synthesis: plentl, schoenheimer, j biol chem 153, 203 (1944).

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory
  • EU Cosmetics Regulation Annex IV, allowed colourant
    Name: CI 75170, Ref no: 113, Annex ref: IV/113

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Guanine is traded under.

HS 2933.59Indicative HS code

Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring, other

World exports in 2024
$18.4B
+10.5% vs 2023, imports $24.8B
2019 to 2024
Top exporters
  1. Ireland43.6%
  2. Switzerland * partner reported26.3%
  3. China7.9%
Top importers
  1. Slovenia30.3%
  2. United States30.1%
  3. Germany15.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Guanine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Guanine, based on the data on this page

What is Guanine?

Guanine is a 2-aminopurine carrying a 6-oxo substituent. It has a role as a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a human metabolite and an algal metabolite. It is a member of 2-aminopurines, an oxopurine and a purine nucleobase.

What is the CAS number of Guanine?

The CAS registry number of Guanine is 73-40-5. Other or deprecated CAS numbers: 66224-64-4, 71660-36-1.

What is the molecular formula and weight of Guanine?

The molecular formula of Guanine is C5H5N5O and its molar mass is 151.13 g/mol.

What is Guanine used for?

Biochemical research, cosmetics. Color additive. Use classes: Cosmetics.

Is Guanine hazardous?

Guanine carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Guanine?

Guanine is usually classified under HS code 293359 (Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Guanine?

CompoundList lists 123 suppliers of Guanine in China, United States, Germany, United Kingdom and 12 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Guanine in India?

5 suppliers in India list Guanine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Guanine?

Suppliers quote Guanine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Guanine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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