Guanine
Also known as 2-Amino-6-hydroxypurine, 2-Aminohypoxanthine, Guanin
Key facts
What buyers check first
- Appearance
- Several desmotropic forms, usually amorphous
- Melting point
- 360 °C
- Boiling point
- SUBLIMES
- Solubility
- CRYSTALLINE POWDER, LOSES WATER @ 100 °C & HYDROGEN CHLORIDE @ 200 °C, PRACTICALLY INSOL…
- HS code
- 293359
- Category
- Dyes and pigments

What is Guanine?
Plain description, key identifiers and synonyms
Guanine is a 2-aminopurine carrying a 6-oxo substituent. It has a role as a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a human metabolite and an algal metabolite. It is a member of 2-aminopurines, an oxopurine and a purine nucleobase. It derives from a hydride of a 9H-purine.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 2-amino-1,7-dihydropurin-6-one
- CAS number
- 73-40-5 CAS number cross-checkedOther or deprecated CAS: 66224-64-4, 71660-36-1
- EC number
- 200-799-8
- Molecular formula
- C5H5N5O
- UNII
- 5Z93L87A1R
- MDL number
- MFCD00071533
- INCI name
- CI 75170, GUANINE
- InChIKey
- UYTPUPDQBNUYGX-UHFFFAOYSA-N
- InChI
- InChI=1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)
- SMILES (canonical and isomeric)
- C1=NC2=C(N1)C(=O)NC(=N2)N
Synonyms
- 2-Amino-6-hydroxypurine
- 2-Aminohypoxanthine
- Guanin
- Mearlmaid
- Guanine enol
- Pearl essence
- Stella Polaris
- Dew Pearl
- Naturon
- Natural white 1
- Natural pearl essence
- 6H-Purin-6-one, 2-amino-1,7-dihydro-
- 2-Amino-1,7-dihydro-6H-purin-6-one
- CI Natural white 1
- C.I. Natural White 1
- Hypoxanthine, 2-amino-
- 6-Hydroxy-2-aminopurine
- 2-amino-1,7-dihydropurin-6-one
- CI 75170
- 2-amino-3,7-dihydropurin-6-one
- C.I. 75170
- C.i. no. 75170 (guanine)
- 2-amino-6,9-dihydro-1H-purin-6-one
- 2-amino-6,7-dihydro-3H-purin-6-one
- 2-amino-1H-purin-6(7H)-one
Show all 36 synonymsShow fewer synonyms
- 2-Amino-6-purinol
- 2-amino-1,9-dihydro-6H-purin-6-one
- 2-amino-9H-purin-6-ol
- 6H-Purin-6-one, 2-amino-1,9-dihydro-
- Mearlmaid AA
- Guanine, 98%
- 2-amino-1,9-dihydropurin-6-one
- 2-Amino-6-hydroxy-1H-purine
- 2-amino-1h-purin-6(9h)-one
- 2-Amino-1,9-dihydro-purin-6-one
- 2-aminohydropurin-6-one
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Appearance | Several desmotropic forms, usually amorphousexp.Measured value |
|---|---|
| Melting point | 360 °Cexp.Measured value |
| Boiling point | SUBLIMESexp.Measured value |
| Solubility | CRYSTALLINE POWDER, LOSES WATER @ 100 °C & HYDROGEN CHLORIDE @ 200 °C, PRACTICALLY INSOL IN WATER, ALC, ETHER, SOL IN ACIDULATED WATER /HYDROCHLORIDE/exp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 151.13 g/molcalc.Computed value |
|---|---|
| Exact mass | 151.0494 Dacalc.Computed value |
| LogP (octanol/water) | -0.77calc.Computed value |
| Topological polar surface area | 100.5 Ųcalc.Computed value |
| Hydrogen bond donors | 3calc.Computed value |
| Hydrogen bond acceptors | 4calc.Computed value |
| Rotatable bonds | 0calc.Computed value |
| Heavy atoms | 11calc.Computed value |
| Rings | 2calc.Computed value |
| Aromatic rings | 2calc.Computed value |
| Fraction sp3 carbons | 0calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
O=c1[nH]cnc2nc[nH]c12
2 rings, 10 atoms, the Hypoxanthine ring system.
586 other chemicals share this scaffoldSafety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H315Causes skin irritation.
- H319Causes serious eye irritation.
- H335May cause respiratory irritation.
Precautionary statements (16)
- P261Avoid breathing dust, fume, gas, mist, vapours or spray.
- P264Wash skin thoroughly after handling.
- P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
- P271Use only outdoors or in a well-ventilated area.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P302 + P352If on skin: Wash with plenty of water.
- P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
- P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P319Get medical help if you feel unwell.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P332 + P317If skin irritation occurs: Get medical help.
- P337 + P317If eye irritation persists: Get medical help.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P403 + P233Store in a well-ventilated place. Keep container tightly closed.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidGuanine suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- China, Jingdezhen ManufacturerUnclaimed profileGuanineGrade, purity and minimum order on requestPrice on request
- India, Mumbai ManufacturerUnclaimed profileGuanineGrade, purity and minimum order on requestPrice on request
- Price on request
- Price on request
- China, XiangyangUnclaimed profileGuanineGrade, purity and minimum order on requestPrice on request
- China, QuanzhouUnclaimed profileGuanineGrade, purity and minimum order on requestPrice on request
- China ManufacturerUnclaimed profileGuanineGrade, purity and minimum order on requestPrice on request
- ChinaUnclaimed profileGuanineGrade, purity and minimum order on requestPrice on request
- China, WuhanUnclaimed profileGuanineGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
123 suppliers in 16 countries
- China49
- United States34
- Germany5
- United Kingdom5
- India5
- Hong Kong4
- and 10 more countries
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Guanine price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Biochemical research, cosmetics.
Color additive.
Use classes: Cosmetics.
Industries and functions
Cosmetic ingredient, INCI name CI 75170(colorant)
Roles
- Escherichia coli metabolite
- Saccharomyces cerevisiae metabolite
- algal metabolite
- animal metabolite
- antineoplastic agent
- bacterial metabolite
- eukaryotic metabolite
- fungal metabolite
- human metabolite
- mammalian metabolite
- metabolite
- mouse metabolite
- pharmaceutical
- prokaryotic metabolite
Functional uses
- Dye
- Opacifer
Cosmetic functions
- Colorant
- Opacifying
Pharmacology
Guanine is a purine base that is a constituent of nucleotides occurring in nucleic acids.
How it is made
Fisher, ber 30, 2226 (1897), traube, ber 33, 1371 (1900). German patents 134,984 (1903), 158,591 (1903), 162,336 (1904). Preparation of (15)n-isotopic guanine following traube's synthesis: plentl, schoenheimer, j biol chem 153, 203 (1944).
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- EU cosmetic ingredient inventory
- EU Cosmetics Regulation Annex IV, allowed colourantName: CI 75170, Ref no: 113, Annex ref: IV/113
United States
- TSCA inventory (USA)Status: Active in US commerce
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Guanine is traded under.
Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring, other
- Ireland43.6%
- Switzerland * partner reported26.3%
- China7.9%
- Slovenia30.3%
- United States30.1%
- Germany15.3%
* Partner reported figures, a lower bound.
The HS code shown for Guanine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Guanine, based on the data on this page
What is Guanine?
What is the CAS number of Guanine?
What is the molecular formula and weight of Guanine?
What is Guanine used for?
Is Guanine hazardous?
What is the HS code of Guanine?
Where can I buy Guanine?
Where can I buy Guanine in India?
What is the price of Guanine?
Guides for buyers
Practical guides that help when you source, ship or handle Guanine
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
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