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Alkaloids

Harmine

Also known as 7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole, Banisterine, Telepathine

CAS 442-51-3Formula C13H12N2OMolar mass 212.25 g/molEC 207-131-4
GHS signal word: Warning. Pictograms: Harmful or irritant 79 suppliers listed
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Harmine chemical structure, C13H12N2O, CAS 442-51-3
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
442-51-3
Formula
C13H12N2O
Molar mass
212.25 g/mol
EC number
207-131-4
HS code
293979
Category
Alkaloids

What is Harmine?

Plain description, key identifiers and synonyms

Harmine is a harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7. It has a role as a metabolite, an EC 1.4.3.4 (monoamine oxidase) inhibitor and an anti-HIV agent. It derives from a hydride of a harman.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
7-methoxy-1-methyl-9H-pyrido[3,4-b]indole
CAS number
442-51-3 CAS number cross-checkedOther or deprecated CAS: 122992-92-1
EC number
207-131-4
Molecular formula
C13H12N2O
UNII
4FHH5G48T7
MDL number
MFCD00004958
InChIKey
BXNJHAXVSOCGBA-UHFFFAOYSA-N
InChI
InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3
SMILES (canonical and isomeric)
CC1=NC=CC2=C1NC3=C2C=CC(=C3)OC

Synonyms

  • 7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole
  • Banisterine
  • Telepathine
  • Leucoharmine
  • Yageine
  • Yajeine
  • 9H-Pyrido[3,4-b]indole, 7-methoxy-1-methyl-
  • 1-Methyl-7-methoxy-beta-carboline
  • 7-Methoxy-1-methyl-9H-pyrido(3,4-b)indole
  • 9H-Pyrido(3,4-b)indole, 7-methoxy-1-methyl-
  • 7-Methoxy-1-methyl-9H-beta-carboline
  • Harmin
  • Harmine (Telepathine)
  • Banisterin
  • Telepathin
  • Yagein
  • Harmin hydrochloride
  • 7-methoxy-1-methylbeta-carboline
  • Garmin
  • HRM
  • Telepathien
  • Telepathine,
  • Yageine,
  • 3anr
  • Harmine (Standard)
Show all 28 synonyms
  • Harmine, 98%
  • 5-23-12-00237 (Beilstein Handbook Reference)
  • DivK1c_006707

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
212.25 g/molcalc.
Exact mass
212.095 Dacalc.
LogP (octanol/water)
3.03calc.
Topological polar surface area
37.91 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
1calc.
Heavy atoms
16calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.15calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2c(c1)[nH]c1cnccc12

c1ccc2c(c1)[nH]c1cnccc12

3 rings, 13 atoms, the beta-Carboline ring system.

374 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302 + H312 + H332Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled.
  • H302Harmful if swallowed.
  • H312Harmful in contact with skin.
  • H319Causes serious eye irritation.
  • H332Harmful if inhaled.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Harmine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 79 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

79 suppliers in 12 countries

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Harmine price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Hallucinogens
  • Monoamine Oxidase Inhibitors

Roles

  • anti-HIV agent
  • antimicrobial agent
  • antiviral agent
  • enzyme inhibitor
  • hypoglycemic agent
  • metabolite
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Harmine is traded under.

HS 2939.79Indicative HS code

Alkaloids of vegetal origin, other than cocaine, ecgonine, salts, esters and other derivatives, not elsewhere…

World exports in 2024
$701M
+18.9% vs 2023, imports $830M
2019 to 2024
Top exporters
  1. Switzerland * partner reported25.3%
  2. Germany21.4%
  3. India * partner reported14.9%
Top importers
  1. United States20.9%
  2. Germany14.7%
  3. Italy14.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Harmine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Harmine, based on the data on this page

What is Harmine?

Harmine is a harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7. It has a role as a metabolite, an EC 1.4.3.4 (monoamine oxidase) inhibitor and an anti-HIV agent. It derives from a hydride of a harman.

What is the CAS number of Harmine?

The CAS registry number of Harmine is 442-51-3. Other or deprecated CAS numbers: 122992-92-1.

What is the molecular formula and weight of Harmine?

The molecular formula of Harmine is C13H12N2O and its molar mass is 212.25 g/mol.

What is Harmine used for?

Known uses and roles of Harmine include anti-hiv agent, antimicrobial agent, antiviral agent, enzyme inhibitor, hypoglycemic agent and 4 more.

Is Harmine hazardous?

Harmine carries the GHS signal word "Warning". Main hazards: harmful if swallowed. harmful in contact with skin. harmful if inhaled, harmful if swallowed, harmful in contact with skin. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Harmine?

Harmine is usually classified under HS code 293979 (Alkaloids, natural or reproduced by synthesis, and their salts, ethers, esters and other…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Harmine?

CompoundList lists 79 suppliers of Harmine in United States, China, United Kingdom, Germany and 8 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Harmine?

Suppliers quote Harmine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Harmine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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