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Amines and amides

(Hydroxymethyl)urea

Also known as N-(Hydroxymethyl)urea, Methylolurea, Monomethylolurea

CAS 1000-82-4Formula C2H6N2O2Molar mass 90.08 g/molEC 213-674-8
GHS signal word: Warning. Pictograms: Harmful or irritant 4 suppliers listed Drug substance
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(Hydroxymethyl)urea chemical structure, C2H6N2O2, CAS 1000-82-4
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Prisms from alcohol
Melting point
111 °C
Solubility
VERY SOL IN WATER, SOL IN METHANOL, ACETIC ACID, SOL IN HOT ALCOHOL, INSOL IN ETHER
HS code
292419
Category
Amines and amides
Illustrative photo, assorted laboratory chemical bottles and jars on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is (Hydroxymethyl)urea?

Plain description, key identifiers and synonyms

N-(hydroxymethyl)urea is a member of the class of ureas that is urea in which one of the amino hydrogens is replaced by a hydroxymethyl group.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
hydroxymethylurea
CAS number
1000-82-4 CAS number cross-checkedOther or deprecated CAS: 78200-36-9
EC number
213-674-8
Molecular formula
C2H6N2O2
UNII
15BY095DMS
InChIKey
VGGLHLAESQEWCR-UHFFFAOYSA-N
InChI
InChI=1S/C2H6N2O2/c3-2(6)4-1-5/h5H,1H2,(H3,3,4,6)
SMILES (canonical and isomeric)
C(NC(=O)N)O

Synonyms

  • N-(Hydroxymethyl)urea
  • Methylolurea
  • Monomethylolurea
  • 1-(Hydroxymethyl)urea
  • N-Methylolurea
  • Mono(hydroxymethyl)urea
  • Urea, (hydroxymethyl)-
  • MILKBODyLotion
  • hydroxymethylurea
  • Urea, hydroxymethyl-
  • Methylol urea
  • Methyl hydroxyurea
  • Methylolureas
  • Hydroxymethyl-urea
  • Urea, N-(hydroxymethyl)-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Prisms from alcoholexp.
Melting point
111 °Cexp.
Solubility
VERY SOL IN WATER, SOL IN METHANOL, ACETIC ACID, SOL IN HOT ALCOHOL, INSOL IN ETHERexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
90.08 g/molcalc.
Exact mass
90.0429 Dacalc.
LogP (octanol/water)
-1.4calc.
Topological polar surface area
75.35 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
1calc.
Heavy atoms
6calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.5calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

(Hydroxymethyl)urea suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 4 suppliers
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Where suppliers are based

4 suppliers in 2 countries

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(Hydroxymethyl)urea price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

In urea-formaldehyde resins, in molding adhesives, for treating textiles and wood.

Industrial uses: Intermediate.

How it is made

Combination of urea and formaldehyde, in the presence of salts or alkaline catalysts.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code (Hydroxymethyl)urea is traded under.

HS 2924.19Indicative HS code

Acyclic amides (including acyclic carbamates) and their derivatives, salts thereof, other

World exports in 2024
$2.38B
−1.7% vs 2023, imports $2.22B
2019 to 2024
Top exporters
  1. China34.7%
  2. Germany12.5%
  3. India * partner reported6.8%
Top importers
  1. United States17.5%
  2. Germany8.8%
  3. India * partner reported6.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for (Hydroxymethyl)urea is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about (Hydroxymethyl)urea, based on the data on this page

What is (Hydroxymethyl)urea?

N-(hydroxymethyl)urea is a member of the class of ureas that is urea in which one of the amino hydrogens is replaced by a hydroxymethyl group.

What is the CAS number of (Hydroxymethyl)urea?

The CAS registry number of (Hydroxymethyl)urea is 1000-82-4. Other or deprecated CAS numbers: 78200-36-9.

What is the molecular formula and weight of (Hydroxymethyl)urea?

The molecular formula of (Hydroxymethyl)urea is C2H6N2O2 and its molar mass is 90.08 g/mol.

What is (Hydroxymethyl)urea used for?

In urea-formaldehyde resins, in molding adhesives, for treating textiles and wood. Industrial uses: Intermediate.

Is (Hydroxymethyl)urea hazardous?

(Hydroxymethyl)urea carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of (Hydroxymethyl)urea?

(Hydroxymethyl)urea is usually classified under HS code 292419 (Acyclic amides (including acyclic carbamates) and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy (Hydroxymethyl)urea?

CompoundList lists 4 suppliers of (Hydroxymethyl)urea in United States and Germany. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of (Hydroxymethyl)urea?

Suppliers quote (Hydroxymethyl)urea on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle (Hydroxymethyl)urea

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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