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Skin conditioning agents and actives

Laurocapram

Also known as Azone, 2H-Azepin-2-one, 1-dodecylhexahydro-, 1-Dodecylazacycloheptan-2-one

CAS 59227-89-3Formula C18H35NOMolar mass 281.48 g/molEC 261-668-9
GHS signal word: Warning. Pictograms: Harmful or irritant 25 suppliers listed
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Laurocapram chemical structure, C18H35NO, CAS 59227-89-3
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Clear, colorless liquid
Melting point
-7 °C
Boiling point
160 °C
Density
0.91 g/cm³
Solubility
Freely soluble in most solvents
HS code
293379
Category
Skin conditioning agents and actives
Illustrative photo, 200 litre steel drums of liquid in a chemical plant
Typical packagingIllustrative packaging image, not the actual product

What is Laurocapram?

Plain description, key identifiers and synonyms

Laurocapram is a member of caprolactams.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-dodecylazepan-2-one
CAS number
59227-89-3 CAS number cross-checked
EC number
261-668-9
Molecular formula
C18H35NO
UNII
1F3X9DRV9X
MDL number
MFCD00190580
INCI name
LAUROCAPRAM
InChIKey
AXTGDCSMTYGJND-UHFFFAOYSA-N
InChI
InChI=1S/C18H35NO/c1-2-3-4-5-6-7-8-9-10-13-16-19-17-14-11-12-15-18(19)20/h2-17H2,1H3
SMILES (canonical and isomeric)
CCCCCCCCCCCCN1CCCCCC1=O

Synonyms

  • Azone
  • 2H-Azepin-2-one, 1-dodecylhexahydro-
  • 1-Dodecylazacycloheptan-2-one
  • Tranzone
  • 1-Dodecylhexahydro-2H-azepin-2-one
  • N-Lauryl caprolactam
  • Laurocapramum
  • 1-n-Dodecylazacycloheptan-2-One
  • N-Dodecyl-epsilon-caprolactam
  • N-Dodecylcaprolactam
  • 1-dodecylazepan-2-one
  • USAF ND-72
  • TraZone
  • N-n-dodecylcaprolactam
  • Laurocapram (USAN/INN)
  • 2H-Azepin-2-one, hexahydro-N-lauryl-
  • Laurocapram (water soluble)
  • 4-21-00-03206 (Beilstein Handbook Reference)
  • 1-dodecylazacycloheptane-2-one
  • 1-Dodecyl-2-azepanone, AldrichCPR
  • Azon, Azone, 1-Dodecylazacycloheptan-2-one, N-Dodecylcaprolactam, 1-Dodecylhexahydro-2H-azepin-2-one
  • laurocapram, azon, azone, 1-dodecylazacycloheptan-2-one, n-dodecylcaprolactam, 1-dodecylhexahydro-2h-azepin-2-one

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Clear, colorless liquidexp.
Melting point
-7 °Cexp.
Boiling point
160 °Cexp.
Density
0.91 g/cm³exp.
Solubility
Freely soluble in most solventsexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
281.48 g/molcalc.
Exact mass
281.2719 Dacalc.
LogP (octanol/water)
5.31calc.
Topological polar surface area
20.31 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
11calc.
Heavy atoms
20calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.94calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CCCCCN1

O=C1CCCCCN1

1 ring, 8 atoms, the Caprolactam ring system.

420 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302 + H312 + H332Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled.
  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
  • H413May cause long lasting harmful effects to aquatic life.
Precautionary statements (21)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Laurocapram suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 25 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

25 suppliers in 2 countries

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Laurocapram price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Caprolactam derivative used to enhance percutaneous absorption of physiologically active agents. Also exhibits intrinsic anti-inflammatory activity.

Relatively low concentrations of the odorless, nonirritating solvent 1-dodecylazacycloheptan-2-one ... have been shown to increase the penetration of antibiotics, corticosteroids, and fluorouracil.

Pharmaceutical aid (excipient).

Cosmetic ingredient, INCI name LAUROCAPRAM(skin conditioning)

Functional uses

  • Softener and conditioner

Cosmetic functions

  • Skin conditioning

Pharmacology

Laurocapram is a percutaneous enhancer. Upon application to the skin, laurocapram interacts with lipids in the stratum corneum and may enhance the ability of the skin to absorb a hydrophilic chemical.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Laurocapram is traded under.

HS 2933.79Indicative HS code

Lactams, other lactams

World exports in 2024
$16.2B
−64.4% vs 2023, imports $15.4B
2019 to 2024
Top exporters
  1. Ireland37.0%
  2. France * partner reported15.6%
  3. Spain11.3%
Top importers
  1. Germany27.8%
  2. Ireland18.9%
  3. Panama * partner reported12.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Laurocapram is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Laurocapram, based on the data on this page

What is Laurocapram?

Laurocapram is a member of caprolactams.

What is the CAS number of Laurocapram?

The CAS registry number of Laurocapram is 59227-89-3.

What is the molecular formula and weight of Laurocapram?

The molecular formula of Laurocapram is C18H35NO and its molar mass is 281.48 g/mol.

What is Laurocapram used for?

Caprolactam derivative used to enhance percutaneous absorption of physiologically active agents. Also exhibits intrinsic anti-inflammatory activity. Relatively low concentrations of the odorless, nonirritating solvent 1-dodecylazacycloheptan-2-one ...

Is Laurocapram hazardous?

Laurocapram carries the GHS signal word "Warning". Main hazards: harmful if swallowed. harmful in contact with skin. harmful if inhaled, causes skin irritation, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Laurocapram?

Laurocapram is usually classified under HS code 293379 (Lactams, other lactams). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Laurocapram?

CompoundList lists 25 suppliers of Laurocapram in China and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Laurocapram?

Suppliers quote Laurocapram on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Laurocapram

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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