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Pharmaceuticals and APIs

Lenacapavir

Also known as GS-HIV, Yeztugo, QNG

CAS 2189684-44-2Formula C39H32ClF10N7O5S2Molar mass 968.30 g/mol
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Lenacapavir chemical structure, C39H32ClF10N7O5S2, CAS 2189684-44-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
2189684-44-2
Formula
C39H32ClF10N7O5S2
Molar mass
968.30 g/mol
HS code
293590
Category
Pharmaceuticals and APIs

What is Lenacapavir?

Plain description, key identifiers and synonyms

Lenacapavir is a first-in-class capsid inhibitor being investigated for use in HIV-1 treatment.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-[(1S)-1-[3-[4-chloro-3-(methanesulfonamido)-1-(2,2,2-trifluoroethyl)indazol-7-yl]-6-(3-methyl-3-methylsulfonylbut-1-ynyl)-2-pyridinyl]-2-(3,5-difluorophenyl)ethyl]-2-[(2S,4R)-5,5-difluoro-9-(trifluoromethyl)-7,8-diazatricyclo[4.3.0.02,4]nona-1(6),8-dien-7-yl]acetamide
CAS number
2189684-44-2
Molecular formula
C39H32ClF10N7O5S2
UNII
A9A0O6FB4H
InChIKey
BRYXUCLEHAUSDY-WEWMWRJBSA-N
InChI
InChI=1S/C39H32ClF10N7O5S2/c1-36(2,63(3,59)60)10-9-21-5-6-22(23-7-8-26(40)30-32(23)57(17-37(43,44)45)54-35(30)55-64(4,61)62)31(51-21)27(13-18-11-19(41)14-20(42)12-18)52-28(58)16-56-34-29(33(53-56)39(48,49)50)24-15-25(24)38(34,46)47/h5-8,11-12,14,24-25,27H,13,15-17H2,1-4H3,(H,52,58)(H,54,55)/t24-,25+,27-/m0/s1
Canonical SMILES
CC(C)(C#Cc1ccc(-c2ccc(Cl)c3c(NS(C)(=O)=O)nn(CC(F)(F)F)c23)c(C(Cc2cc(F)cc(F)c2)NC(=O)Cn2nc(C(F)(F)F)c3c2C(F)(F)C2CC32)n1)S(C)(=O)=O
Isomeric SMILES
CC(C)(C#CC1=NC(=C(C=C1)C2=C3C(=C(C=C2)Cl)C(=NN3CC(F)(F)F)NS(=O)(=O)C)[C@H](CC4=CC(=CC(=C4)F)F)NC(=O)CN5C6=C([C@H]7C[C@H]7C6(F)F)C(=N5)C(F)(F)F)S(=O)(=O)C

Synonyms

  • GS-HIV
  • Yeztugo
  • QNG
  • Lenacapavir (USAN/INN)
  • Lenacapavir(GS-6207)?
  • Yeztugo (twice-yearly injection)
  • WHO 11108

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
968.30 g/molcalc.
Exact mass
967.1435 Dacalc.
LogP (octanol/water)
7.66calc.
Topological polar surface area
157.9 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
8calc.
Rotatable bonds
11calc.
Heavy atoms
64calc.
Rings
7calc.
Aromatic rings
5calc.
Fraction sp3 carbons
0.39calc.
Formal charge
0calc.
Stereocentres
3calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(Cn1ncc2c1CC1CC21)NC(Cc1ccccc1)c1ncccc1-c1cccc2cn[nH]c12

O=C(Cn1ncc2c1CC1CC21)NC(Cc1ccccc1)c1ncccc1-c1cccc2cn[nH]c12

7 rings, 36 atoms.

7 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Lenacapavir suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 9 suppliers
9 of 9 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

9 suppliers in 3 countries

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Lenacapavir price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Roles

  • anti-HIV agent
  • antimicrobial agent
  • antiviral agent

Pharmacology

Lenacapavir is a Human Immunodeficiency Virus 1 Capsid Inhibitor. The mechanism of action of lenacapavir is as a HIV Capsid Inhibitor, and Cytochrome P450 3A Inhibitor, and P-Glycoprotein Inhibitor, and Breast Cancer Resistance Protein Inhibitor.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Lenacapavir is traded under.

HS 2935.90Indicative HS code

Sulphonamides, other

World exports in 2024
$5.64B
−11.0% vs 2023, imports $8.56B
2019 to 2024
Top exporters
  1. Ireland43.1%
  2. China12.0%
  3. India * partner reported9.5%
Top importers
  1. United States23.6%
  2. Slovenia19.1%
  3. Spain11.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Lenacapavir is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Lenacapavir, based on the data on this page

What is Lenacapavir?

Lenacapavir is a first-in-class capsid inhibitor being investigated for use in HIV-1 treatment.

What is the CAS number of Lenacapavir?

The CAS registry number of Lenacapavir is 2189684-44-2.

What is the molecular formula and weight of Lenacapavir?

The molecular formula of Lenacapavir is C39H32ClF10N7O5S2 and its molar mass is 968.30 g/mol.

What is Lenacapavir used for?

Known uses and roles of Lenacapavir include anti-hiv agent, antimicrobial agent and antiviral agent.

Is Lenacapavir hazardous?

No GHS hazard classification for Lenacapavir is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Lenacapavir?

Lenacapavir is usually classified under HS code 293590 (Sulphonamides, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Lenacapavir?

CompoundList lists 9 suppliers of Lenacapavir in China, India and South Korea. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Lenacapavir in India?

2 suppliers in India list Lenacapavir on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Lenacapavir?

Suppliers quote Lenacapavir on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Lenacapavir

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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