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Cosmetic antioxidants

Maslinic acid

Also known as Crategolic acid, Crataegolic acid, Maslic acid

CAS 4373-41-5Formula C30H48O4Molar mass 472.71 g/molEC 610-137-3
12 suppliers listed
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Maslinic acid chemical structure, C30H48O4, CAS 4373-41-5
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Crystalline solid
Melting point
249 to 250 °C
Density
1.15 g/cm³
Solubility
Solubility of 0.3 mg/mL in a 1:2 solution of Ethanol:Buffered Water (pH 7.2) at 25 °C
HS code
291819
Category
Cosmetic antioxidants
Illustrative photo, 25 kg white woven sacks of powder on a pallet in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Maslinic acid?

Plain description, key identifiers and synonyms

Maslinic acid is a pentacyclic triterpenoid that is olean-12-ene substituted by hydroxy groups at positions 2 and 3 and a carboxy group at position 28 (the 2alpha,3beta stereoisomer). It is isolated from Olea europaea and Salvia canariensis and exhibits anti-inflammatory, antioxidant and antineoplastic activity. It has a role as an antioxidant, an antineoplastic agent, an anti-inflammatory agent and a plant metabolite. It is a pentacyclic triterpenoid and a dihydroxy monocarboxylic acid. It derives from a hydride of an oleanane.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
CAS number
4373-41-5 CAS number cross-checked
EC number
610-137-3
Molecular formula
C30H48O4
UNII
E233J88OHQ
MDL number
MFCD00049293
INCI name
MASLINIC ACID
InChIKey
MDZKJHQSJHYOHJ-LLICELPBSA-N
InChI
InChI=1S/C30H48O4/c1-25(2)12-14-30(24(33)34)15-13-28(6)18(19(30)16-25)8-9-22-27(5)17-20(31)23(32)26(3,4)21(27)10-11-29(22,28)7/h8,19-23,31-32H,9-17H2,1-7H3,(H,33,34)/t19-,20+,21-,22+,23-,27-,28+,29+,30-/m0/s1
Canonical SMILES
CC1(C)CCC2(C(=O)O)CCC3(C)C(=CCC4C5(C)CC(O)C(O)C(C)(C)C5CCC43C)C2C1
Isomeric SMILES
C[C@@]12CC[C@@H]3[C@@]([C@H]1CC=C4[C@]2(CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)C)(C[C@H]([C@@H](C3(C)C)O)O)C

Synonyms

  • Crategolic acid
  • Crataegolic acid
  • Maslic acid
  • Masilinic acid
  • 2alpha-hydroxyoleanolic acid
  • 2alpha,3beta-dihydroxyurs-12-en-29-oic acid
  • 2-hydroxyoleanolic acid
  • Olean-12-en-28-oic acid, 2,3-dihydroxy-, (2alpha,3beta)-
  • (2alpha, 3beta)-2,3-dihydroxyolean-12-en-28-oic acid
  • (2beta, 3alpha)-2,3-dihydroxyolean-12-en-28-oic acid
  • (2alpha, 3beta)-2,3-dihydroxy-olean-12-en-28-oic acid
  • olean-12-en-28-oic acid, 2,3-dihydroxy-, (2alpha, 3beta)-
  • 2alpha,3beta-dihydroxyolean-12-en-28-oic acid
  • Maslinicacid
  • maslinatic acid
  • Maslinic-acid
  • Maslinic acid (Standard)
  • alpha-hydroxyoleanolic acid
  • 2alpha-hydroxyl oleanolic acid
  • Maslinic acid, analytical standard
  • Maslinic acid, >=98% (HPLC)
  • Crategolic acid, 2-Hydroxyoleanolic acid
  • 2alpha,3beta-dihydroxyolean-12-en-28-acid
  • 2alpha,3beta-dihydroxy-12-oleanen-28-oic acid
  • 2alpha,3beta-dihydroxy-olean-12-en-28-oic acid
Show all 30 synonyms
  • (2alpha,3beta)- 2,3-dihydroxy-Olean-12-en-28-oate
  • (2alpha,3beta)-2,3-dihydroxyolean-12-en-28-oic acid
  • (2alpha,3beta)-2,3-dihydroxy-Olean-12-en-28-oate
  • (2alpha,3beta)- 2,3-dihydroxy-Olean-12-en-28-oic acid
  • (2alpha,3beta)-2,3-dihydroxy-Olean-12-en-28-oic acid

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystalline solidexp.
Melting point
249 to 250 °Cexp.
Density
1.15 g/cm³exp.
Solubility
Solubility of 0.3 mg/mL in a 1:2 solution of Ethanol:Buffered Water (pH 7.2) at 25 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
472.71 g/molcalc.
Exact mass
472.3553 Dacalc.
LogP (octanol/water)
6.2calc.
Topological polar surface area
77.76 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
1calc.
Heavy atoms
34calc.
Rings
5calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.9calc.
Formal charge
0calc.
Stereocentres
9calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1=C2C3CCCCC3CCC2C2CCC3CCCCC3C2C1

C1=C2C3CCCCC3CCC2C2CCC3CCCCC3C2C1

5 rings, 22 atoms.

402 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Maslinic acid suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 12 suppliers
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Where suppliers are based

12 suppliers in 3 countries

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Maslinic acid price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Maslinic acid is reported to have potent antioxidant, anti-cancer, anti-HIV and anti-inflammatory activities.

Maslinic acid is a protease inhibitor that, among other features, has the capacity of regulating cell growth. It is useful for cancer treatment, as it allows to control the hyperplasia and hypertrophy processes, typical of this disease.

Investigated the mechanisms of maslinic acid with regard to its inhibitory effects on the growth of HT29 colon-cancer cells. High concentrations of maslinic acid are present in the protective wax-like coating of olives. Our results show that treatment with maslinic acid results in a significant inhibition of cell proliferation in a dose-dependent manner and causes apoptotic death in colon-cancer cells.

Read more

We found that it inhibits considerably the expression of Bcl-2 whilst increasing that of Bax, it also stimulates the release of mitochondrial cytochrome-c and activates caspase-9 and caspase-3. All these results point clearly to the activation of the mitochondrial apoptotic pathway in response to the treatment of HT29 colon-cancer cells with maslinic acid. Our results suggest that maslinic acid has the potential to provide significant natural defence against colon-cancer.

Maslinic acid has multiple biological and antimicrobial activities including anti-malarial activity.

Cosmetic ingredient, INCI name MASLINIC ACID(antioxidant, skin conditioning)

Roles

  • anti-inflammatory agent
  • antineoplastic agent
  • antioxidant
  • eukaryotic metabolite
  • metabolite
  • pharmaceutical
  • plant metabolite

Functional uses

  • Antioxidant
  • Softener and conditioner

Cosmetic functions

  • Antioxidant
  • Skin conditioning

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Maslinic acid is traded under.

HS 2918.19Indicative HS code

Carboxylic acids with alcohol function but without other oxygen function, their…

World exports in 2024
$1.37B
+0.5% vs 2023, imports $1.18B
2019 to 2024
Top exporters
  1. China23.7%
  2. Italy14.7%
  3. India * partner reported12.0%
Top importers
  1. Germany11.7%
  2. South Korea9.8%
  3. Italy9.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Maslinic acid is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Maslinic acid, based on the data on this page

What is Maslinic acid?

Maslinic acid is a pentacyclic triterpenoid that is olean-12-ene substituted by hydroxy groups at positions 2 and 3 and a carboxy group at position 28 (the 2alpha,3beta stereoisomer). It is isolated from Olea europaea and Salvia canariensis and exhibits anti-inflammatory, antioxidant and antineoplastic activity.

What is the CAS number of Maslinic acid?

The CAS registry number of Maslinic acid is 4373-41-5.

What is the molecular formula and weight of Maslinic acid?

The molecular formula of Maslinic acid is C30H48O4 and its molar mass is 472.71 g/mol.

What is Maslinic acid used for?

Maslinic acid is reported to have potent antioxidant, anti-cancer, anti-HIV and anti-inflammatory activities. Maslinic acid is a protease inhibitor that, among other features, has the capacity of regulating cell growth.

Is Maslinic acid hazardous?

No GHS hazard classification for Maslinic acid is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Maslinic acid?

Maslinic acid is usually classified under HS code 291819 (Carboxylic acids with alcohol function but without other oxygen function, their…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Maslinic acid?

CompoundList lists 12 suppliers of Maslinic acid in China, Spain and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Maslinic acid?

Suppliers quote Maslinic acid on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Maslinic acid

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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