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Meldonium

Also known as Mildronate, Kvaterin, 3-(2,2,2-trimethylhydrazine)propionate

Meldonium chemical structure, C6H14N2O2, CAS 76144-81-5
2D chemical structure

Key facts

What buyers check first

CAS number
76144-81-5
Formula
C6H14N2O2
Molar mass
146.19 g/mol
EC number
682-135-0
HS code
291590
Category
Cardiovascular and metabolic drugs

What is Meldonium?

Plain description, key identifiers and synonyms

Meldonium is an ammonium betaine that is beta-alaninate in which one of the amino hydrogens is replaced by a trimethylamino group. A clinically used cardioprotective drug that is used for treatment of heart failure, myocardial infarction, arrhythmia, atherosclerosis and diabetes. It has a role as an EC 1.14.11.1 (gamma-butyrobetaine dioxygenase) inhibitor, a neuroprotective agent and a cardioprotective agent.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-[(trimethylazaniumyl)amino]propanoate
CAS number
76144-81-5 CAS number cross-checkedOther or deprecated CAS: 802032-35-5
EC number
682-135-0
Molecular formula
C6H14N2O2
UNII
73H7UDN6EC
MDL number
MFCD00876389
InChIKey
PVBQYTCFVWZSJK-UHFFFAOYSA-N
InChI
InChI=1S/C6H14N2O2/c1-8(2,3)7-5-4-6(9)10/h7H,4-5H2,1-3H3
SMILES (canonical and isomeric)
C[N+](C)(C)NCCC(=O)[O-]

Synonyms

  • Mildronate
  • Kvaterin
  • 3-(2,2,2-trimethylhydrazine)propionate
  • Quaterine
  • 3-(2,2,2-Trimethyldiazaniumyl)propanoate
  • meldonio
  • 3-(2,2,2-trimethylhydrazin-2-ium-1-yl)propanoate
  • 3-(2,2,2-trimethylhydrazinium)propionate
  • mildronat
  • mindronate
  • Vasonat
  • 3-TMHP
  • N-trimethylhydrazine-3-propionate
  • Quaterin
  • 3-(2,2,2-trimethyldiazan-2-ium-1-yl)propanoate
  • 3-[(trimethylazaniumyl)amino]propanoate
  • Mildronate,Meldonium
  • Meldonium (INN)
  • 2-(2-Carboxyethyl)-1,1,1-trimethylhydrazinium, inner salt
  • 3-[(trimethylamino)amino]propanoic acid
  • 3-[(trimethylammonio)amino]propanoate
  • 2-(2-Carboxyethyl)-1,1,1-trimethylhydrazinium hydroxide inner salt
  • Meldonium, MET-88, Quaterin
  • (3-(2,2,2-Trimethylhydroazini
  • 2-(2-Carboxyethyl)-1,1,1-trimethyl Hydrazinium Inner Salt
Show all 31 synonyms
  • Hydrazinium, 2-(2-carboxyethyl)-1,1,1-trimethyl-, hydroxide, inner salt
  • Meldonium dihydrate - Bio-X trade mark
  • 3-(2,2,2-trimethyldiazan-2-iumyl)propanoate
  • Meldonium dihydrate, >=98% (HPLC), powder
  • 1,1,1-Trimethyl-2-(2-carboxyethyl)hydrazine zwitterion
  • Meldonium dihydrate, European Pharmacopoeia (EP) Reference Standard

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
146.19 g/molcalc.
Exact mass
146.1055 Dacalc.
LogP (octanol/water)
-1.66calc.
Topological polar surface area
52.16 ร…ยฒcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
4calc.
Heavy atoms
10calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.83calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Meldonium suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 21 suppliers
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Meldonium price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Adjuvants, Immunologic
  • Cardiovascular Agents

Roles

  • cardioprotective agent
  • cardiovascular drug
  • enzyme inhibitor
  • neuroprotective agent
  • pharmaceutical
  • protective agent

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Meldonium is traded under.

HS 2915.90Indicative HS code

Saturated acyclic monocarboxylic acids, anhydrides, halides, peroxides, peroxyacids and halogenatedโ€ฆ

World exports in 2024
$3.42B
+5.6% vs 2023, imports $3.55B
2019 to 2024
Top exporters
  1. Indonesia15.9%
  2. Germany13.0%
  3. Malaysia12.4%
Top importers
  1. China14.4%
  2. Netherlands11.7%
  3. United States11.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Meldonium is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Meldonium, based on the data on this page

What is Meldonium?

Meldonium is an ammonium betaine that is beta-alaninate in which one of the amino hydrogens is replaced by a trimethylamino group. A clinically used cardioprotective drug that is used for treatment of heart failure, myocardial infarction, arrhythmia, atherosclerosis and diabetes.

What is the CAS number of Meldonium?

The CAS registry number of Meldonium is 76144-81-5. Other or deprecated CAS numbers: 802032-35-5.

What is the molecular formula and weight of Meldonium?

The molecular formula of Meldonium is C6H14N2O2 and its molar mass is 146.19 g/mol.

What is Meldonium used for?

Known uses and roles of Meldonium include cardiovascular drugs in pharmaceuticals, cardioprotective agent, cardiovascular drug, enzyme inhibitor, neuroprotective agent and 4 more.

Is Meldonium hazardous?

Meldonium carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Meldonium?

Meldonium is usually classified under HS code 291590 (Saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides andโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Meldonium?

CompoundList lists 21 suppliers of Meldonium in China, Canada, United States, Switzerland and 4 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Meldonium?

Suppliers quote Meldonium on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Meldonium

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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