Meldonium
Also known as Mildronate, Kvaterin, 3-(2,2,2-trimethylhydrazine)propionate
Key facts
What buyers check first
- CAS number
- 76144-81-5
- Formula
- C6H14N2O2
- Molar mass
- 146.19 g/mol
- EC number
- 682-135-0
- HS code
- 291590
- Category
- Cardiovascular and metabolic drugs
What is Meldonium?
Plain description, key identifiers and synonyms
Meldonium is an ammonium betaine that is beta-alaninate in which one of the amino hydrogens is replaced by a trimethylamino group. A clinically used cardioprotective drug that is used for treatment of heart failure, myocardial infarction, arrhythmia, atherosclerosis and diabetes. It has a role as an EC 1.14.11.1 (gamma-butyrobetaine dioxygenase) inhibitor, a neuroprotective agent and a cardioprotective agent.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 3-[(trimethylazaniumyl)amino]propanoate
- CAS number
- 76144-81-5 CAS number cross-checkedOther or deprecated CAS: 802032-35-5
- EC number
- 682-135-0
- Molecular formula
- C6H14N2O2
- UNII
- 73H7UDN6EC
- MDL number
- MFCD00876389
- InChIKey
- PVBQYTCFVWZSJK-UHFFFAOYSA-N
- InChI
- InChI=1S/C6H14N2O2/c1-8(2,3)7-5-4-6(9)10/h7H,4-5H2,1-3H3
- SMILES (canonical and isomeric)
- C[N+](C)(C)NCCC(=O)[O-]
Synonyms
- Mildronate
- Kvaterin
- 3-(2,2,2-trimethylhydrazine)propionate
- Quaterine
- 3-(2,2,2-Trimethyldiazaniumyl)propanoate
- meldonio
- 3-(2,2,2-trimethylhydrazin-2-ium-1-yl)propanoate
- 3-(2,2,2-trimethylhydrazinium)propionate
- mildronat
- mindronate
- Vasonat
- 3-TMHP
- N-trimethylhydrazine-3-propionate
- Quaterin
- 3-(2,2,2-trimethyldiazan-2-ium-1-yl)propanoate
- 3-[(trimethylazaniumyl)amino]propanoate
- Mildronate,Meldonium
- Meldonium (INN)
- 2-(2-Carboxyethyl)-1,1,1-trimethylhydrazinium, inner salt
- 3-[(trimethylamino)amino]propanoic acid
- 3-[(trimethylammonio)amino]propanoate
- 2-(2-Carboxyethyl)-1,1,1-trimethylhydrazinium hydroxide inner salt
- Meldonium, MET-88, Quaterin
- (3-(2,2,2-Trimethylhydroazini
- 2-(2-Carboxyethyl)-1,1,1-trimethyl Hydrazinium Inner Salt
Show all 31 synonymsShow fewer synonyms
- Hydrazinium, 2-(2-carboxyethyl)-1,1,1-trimethyl-, hydroxide, inner salt
- Meldonium dihydrate - Bio-X trade mark
- 3-(2,2,2-trimethyldiazan-2-iumyl)propanoate
- Meldonium dihydrate, >=98% (HPLC), powder
- 1,1,1-Trimethyl-2-(2-carboxyethyl)hydrazine zwitterion
- Meldonium dihydrate, European Pharmacopoeia (EP) Reference Standard
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 146.19 g/molcalc.Computed value |
|---|---|
| Exact mass | 146.1055 Dacalc.Computed value |
| LogP (octanol/water) | -1.66calc.Computed value |
| Topological polar surface area | 52.16 ร
ยฒcalc.Computed value |
| Hydrogen bond donors | 1calc.Computed value |
| Hydrogen bond acceptors | 3calc.Computed value |
| Rotatable bonds | 4calc.Computed value |
| Heavy atoms | 10calc.Computed value |
| Rings | 0calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 0.83calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H315Causes skin irritation.
- H319Causes serious eye irritation.
- H335May cause respiratory irritation.
Precautionary statements (16)
- P261Avoid breathing dust, fume, gas, mist, vapours or spray.
- P264Wash skin thoroughly after handling.
- P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
- P271Use only outdoors or in a well-ventilated area.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P302 + P352If on skin: Wash with plenty of water.
- P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
- P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P319Get medical help if you feel unwell.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P332 + P317If skin irritation occurs: Get medical help.
- P337 + P317If eye irritation persists: Get medical help.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P403 + P233Store in a well-ventilated place. Keep container tightly closed.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidMeldonium suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- Price on request
- ChinaUnclaimed profileMildronateGrade, purity and minimum order on requestPrice on request
- ChinaUnclaimed profileMildronateGrade, purity and minimum order on requestPrice on request
- China, NantongUnclaimed profileMildronateGrade, purity and minimum order on requestPrice on request
- China, JinanUnclaimed profileMeldoniumGrade, purity and minimum order on requestPrice on request
- Romania, Otopeni ManufacturerUnclaimed profileMeldoniumGrade, purity and minimum order on requestPrice on request
- China, Chengdu ManufacturerUnclaimed profileMildronateGrade, purity and minimum order on requestPrice on request
- Price on request
- China, Shaoxing ManufacturerUnclaimed profileMildronateGrade, purity and minimum order on requestPrice on request
- United States, Redwood CityUnclaimed profileMeldoniumGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
21 suppliers in 8 countries
- China12
- Canada2
- United States2
- Switzerland1
- Hong Kong1
- Romania1
- and 2 more countries
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Meldonium price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Industries and functions
Pharmacological actions
- Adjuvants, Immunologic
- Cardiovascular Agents
Roles
- cardioprotective agent
- cardiovascular drug
- enzyme inhibitor
- neuroprotective agent
- pharmaceutical
- protective agent
Regulatory status
Inventories, regulations and trade controls that list this substance
No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Meldonium is traded under.
Saturated acyclic monocarboxylic acids, anhydrides, halides, peroxides, peroxyacids and halogenatedโฆ
- China14.4%
- Netherlands11.7%
- United States11.5%
The HS code shown for Meldonium is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Meldonium, based on the data on this page
What is Meldonium?
What is the CAS number of Meldonium?
What is the molecular formula and weight of Meldonium?
What is Meldonium used for?
Is Meldonium hazardous?
What is the HS code of Meldonium?
Where can I buy Meldonium?
What is the price of Meldonium?
Guides for buyers
Practical guides that help when you source, ship or handle Meldonium
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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