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Analgesics and anti-inflammatories

Meloxicam

Also known as Mobic, Metacam, Mobicox

CAS 71125-38-7Formula C14H13N3O4S2Molar mass 351.41 g/molEC 615-253-8
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Serious health hazard 152 suppliers listed Drug substance
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Meloxicam chemical structure, C14H13N3O4S2, CAS 71125-38-7
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Crystals from ethylene chloride
Melting point
254 °C
Solubility
Very slightly soluble in methanol. Practically insoluble in water, with higher solubilit…
HS code
293590
Category
Analgesics and anti-inflammatories
Illustrative photo, assorted laboratory chemical bottles and jars on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Meloxicam?

Plain description, key identifiers and synonyms

Meloxicam is a benzothiazine that is piroxicam in which the pyridin-2-yl group is replaced by a 5-methyl-1,3-thiazol-2-yl group. A non-steroidal anti-inflammatory drug and selective inhibitor of COX-2, it is used particularly for the management of rheumatoid arthritis. It has a role as a non-steroidal anti-inflammatory drug, an analgesic, an antirheumatic drug and a cyclooxygenase 2 inhibitor. It is a monocarboxylic acid amide, a member of 1,3-thiazoles and a benzothiazine.

Meloxicam is a nonsteroidal anti-inflammatory drug.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1λ6,2-benzothiazine-3-carboxamide
CAS number
71125-38-7 CAS number cross-checked
EC number
615-253-8
Molecular formula
C14H13N3O4S2
UNII
VG2QF83CGL
MDL number
MFCD00868752
InChIKey
ZRVUJXDFFKFLMG-UHFFFAOYSA-N
InChI
InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,18H,1-2H3,(H,15,16,19)
SMILES (canonical and isomeric)
CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O

Synonyms

  • Mobic
  • Metacam
  • Mobicox
  • Movalis
  • Movatec
  • Mobec
  • Coxicam
  • Meloxivet
  • Melfax
  • UH-AC 62XX
  • Meloxicamum
  • Meloxidolor
  • Meloxoral
  • Rheumocam
  • Vivlodex
  • Melosus
  • RevitaCAM
  • Acticam
  • Contacera
  • Emdocam
  • Flexicam
  • Inflacam
  • Loxicom
  • Melovem
  • Meloxidyl
Show all 39 synonyms
  • Recocam
  • UHAC-62XX
  • 4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
  • UH-AC-62 XX
  • Anjeso
  • QMIIZ ODT
  • miloxicam
  • Zeleris component meloxicam
  • Symbravo component meloxicam
  • Zynrelef component meloxicam
  • 4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1lambda6,2-benzothiazine-3-carboxamide
  • 2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-(5-methylthiazolyl)-, 1,1-dioxide
  • Masflex
  • Movicox

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystals from ethylene chlorideexp.
Melting point
254 °Cexp.
Solubility
Very slightly soluble in methanol. Practically insoluble in water, with higher solubility observed in strong acids and bases.exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
351.41 g/molcalc.
Exact mass
351.0347 Dacalc.
LogP (octanol/water)
1.95calc.
Topological polar surface area
99.6 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
2calc.
Heavy atoms
23calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.14calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(Nc1nccs1)C1=Cc2ccccc2S(=O)(=O)N1

O=C(Nc1nccs1)C1=Cc2ccccc2S(=O)(=O)N1

3 rings, 20 atoms.

18 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H301Toxic if swallowed.
  • H360May damage fertility or the unborn child.
  • H412Harmful to aquatic life with long lasting effects.
Precautionary statements (11)
  • P203Obtain, read and follow all safety instructions before use.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P318If exposed or concerned, get medical advice.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Meloxicam suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 152 suppliers
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Where suppliers are based

152 suppliers in 19 countries

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Meloxicam price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Nonsteroidal anti-inflammatory drug used to relieve the symptoms of arthritis, primary dysmenorrhea, fever, and as an analgesic ...

Therapeutic category: Anti-inflammatory.

Therapeutic category (veterinary): Anti-inflammatory.

Use classes: Pharmaceuticals, Animal Drugs.

Pharmacological actions

  • Anti-Inflammatory Agents, Non-Steroidal
  • Cyclooxygenase 2 Inhibitors

Roles

  • analgesic
  • anti-inflammatory agent
  • anti-inflammatory drug
  • antibacterial agent
  • antibacterial drug
  • antiinfective agent
  • antimicrobial agent
  • antimicrobial drug
  • antimycobacterial drug
  • antineoplastic agent
  • antirheumatic drug
  • antitubercular agent
  • cyclooxygenase 2 inhibitor
  • enzyme inhibitor
  • non-steroidal anti-inflammatory drug
  • pharmaceutical

Pharmacology

Meloxicam is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of meloxicam is as a Cyclooxygenase Inhibitor.

How it is made

Reaction of benzothiazolo-3(2H)-one-1,1-dioxide with methyl chloroacetate gives the methyl 2(3H)-acetate derivative, which is isomerized with sodium methoxide in toluene-tert-butanol yielding methyl 4-hydroxy-2H-1,2-benzothiazine-3-carboxylate-1,1-dioxide. Subsequent methylation with methyl iodide in methanol yields the 2-methyl compound. Finally this compound is treated with 2-amino-5-methylthiazole in xylene.

Preparation: G. Trummlitz et al., DE 2756113 (1979 to Thomae), eidem, US 4233299 (1980 to Boehringer Ingelheim).

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Meloxicam is traded under.

HS 2935.90Indicative HS code

Sulphonamides, other

World exports in 2024
$5.64B
−11.0% vs 2023, imports $8.56B
2019 to 2024
Top exporters
  1. Ireland43.1%
  2. China12.0%
  3. India * partner reported9.5%
Top importers
  1. United States23.6%
  2. Slovenia19.1%
  3. Spain11.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Meloxicam is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Meloxicam, based on the data on this page

What is Meloxicam?

Meloxicam is a benzothiazine that is piroxicam in which the pyridin-2-yl group is replaced by a 5-methyl-1,3-thiazol-2-yl group. A non-steroidal anti-inflammatory drug and selective inhibitor of COX-2, it is used particularly for the management of rheumatoid arthritis.

What is the CAS number of Meloxicam?

The CAS registry number of Meloxicam is 71125-38-7.

What is the molecular formula and weight of Meloxicam?

The molecular formula of Meloxicam is C14H13N3O4S2 and its molar mass is 351.41 g/mol.

What is Meloxicam used for?

Nonsteroidal anti-inflammatory drug used to relieve the symptoms of arthritis, primary dysmenorrhea, fever, and as an analgesic ... Therapeutic category: Anti-inflammatory. Therapeutic category (veterinary): Anti-inflammatory. Use classes: Pharmaceuticals, Animal Drugs.

Is Meloxicam hazardous?

Meloxicam carries the GHS signal word "Danger". Main hazards: toxic if swallowed, may damage fertility or the unborn child, harmful to aquatic life with long lasting effects. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Meloxicam?

Meloxicam is usually classified under HS code 293590 (Sulphonamides, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Meloxicam?

CompoundList lists 152 suppliers of Meloxicam in China, United States, India, Germany and 15 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Meloxicam in India?

28 suppliers in India list Meloxicam on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Meloxicam?

Suppliers quote Meloxicam on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Meloxicam

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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