Meropenem
Also known as Merrem, Meropenem anhydrous, Meropenemum
Key facts
What buyers check first
- CAS number
- 96036-03-2
- Formula
- C17H25N3O5S
- Molar mass
- 383.47 g/mol
- EC number
- 641-424-1
- HS code
- 294190
- Category
- Antibiotics and anti-infectives
What is Meropenem?
Plain description, key identifiers and synonyms
Meropenem is a carbapenemcarboxylic acid in which the azetidine and pyrroline rings carry 1-hydroxymethyl and in which the azetidine and pyrroline rings carry 1-hydroxymethyl and 5-(dimethylcarbamoyl)pyrrolidin-3-ylthio substituents respectively. It has a role as an antibacterial agent, an antibacterial drug and a drug allergen. It is an organic sulfide, a carbapenemcarboxylic acid, a pyrrolidinecarboxamide and an alpha,beta-unsaturated monocarboxylic acid.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (4R,5S,6S)-3-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
- CAS number
- 96036-03-2 CAS number cross-checkedOther or deprecated CAS: 119478-56-7
- EC number
- 641-424-1
- Molecular formula
- C17H25N3O5S
- UNII
- YOP6PX0BAO
- InChIKey
- DMJNNHOOLUXYBV-PQTSNVLCSA-N
- InChI
- InChI=1S/C17H25N3O5S/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4/h7-12,18,21H,5-6H2,1-4H3,(H,24,25)/t7-,8-,9+,10+,11-,12-/m1/s1
- Canonical SMILES
- CC(O)C1C(=O)N2C(C(=O)O)=C(SC3CNC(C(=O)N(C)C)C3)C(C)C12
- Isomeric SMILES
- C[C@@H]1[C@@H]2[C@H](C(=O)N2C(=C1S[C@H]3C[C@H](NC3)C(=O)N(C)C)C(=O)O)[C@@H](C)O
Synonyms
- Merrem
- Meropenem anhydrous
- Meropenemum
- Antibiotic SM 7338
- Meronem
- Merrem I.V.
- MEPM
- Meropenem, anhydrous
- (4R,5S,6S)-3-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
- Merrem IV
- (4r,5s,6s)-3-{[(3s,5s)-5-(Dimethylcarbamoyl)pyrrolidin-3-Yl]sulfanyl}-6-[(1r)-1-Hydroxyethyl]-4-Methyl-7-Oxo-1-Azabicyclo[3.2.0]hept-2-Ene-2-Carboxylic Acid
- Meropenem (as trihydrate)
- ICI 194,660
- (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
- Vabomere component meropenem
- (4R,5S,6S)-3-(((3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl)sulfanyl)-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid
- (4R,5S,6S)-3-(((3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl)thio)-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid
- (4R,5S,6S)-3-((3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl)sulfanyl-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid
- Meropenem and Sodium Chloride
- Meropenem and sodium chloride in duplex container
- (4R,5S,6S)-3-((3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-1-ium-3-yl)sulfanyl-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylate
- Meropenem (INN)
- SM 7338
- (4R,5S,6S)-3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
- ICI 194660
Show all 32 synonymsShow fewer synonyms
- (4R,5S,6S)-3-(((3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl)thio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
- Meropenem sodium carbonate
- Meropen
- SM 7338 trihydrate
- Meronem (TN)
- Merrem I.V. (TN)
- Meropenem (closed form)
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 383.47 g/molcalc.Computed value |
|---|---|
| Exact mass | 383.1515 Dacalc.Computed value |
| LogP (octanol/water) | -0.31calc.Computed value |
| Topological polar surface area | 110.2 Ųcalc.Computed value |
| Hydrogen bond donors | 3calc.Computed value |
| Hydrogen bond acceptors | 6calc.Computed value |
| Rotatable bonds | 5calc.Computed value |
| Heavy atoms | 26calc.Computed value |
| Rings | 3calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 0.71calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 6calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H315Causes skin irritation.
- H317May cause an allergic skin reaction.
- H319Causes serious eye irritation.
- H334May cause allergy or asthma symptoms or breathing difficulties if inhaled.
- H335May cause respiratory irritation.
Precautionary statements (23)
- P233Keep container tightly closed.
- P260Do not breathe dust, fume, gas, mist, vapours or spray.
- P261Avoid breathing dust, fume, gas, mist, vapours or spray.
- P264Wash skin thoroughly after handling.
- P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
- P271Use only outdoors or in a well-ventilated area.
- P272Contaminated work clothing should not be allowed out of the workplace.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P284In case of inadequate ventilation wear respiratory protection.
- P302 + P352If on skin: Wash with plenty of water.
- P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
- P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P319Get medical help if you feel unwell.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P332 + P317If skin irritation occurs: Get medical help.
- P333 + P317If skin irritation or rash occurs: Get medical help.
- P337 + P317If eye irritation persists: Get medical help.
- P342 + P316If experiencing respiratory symptoms: Get emergency medical help immediately.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P403Store in a well-ventilated place.
- P403 + P233Store in a well-ventilated place. Keep container tightly closed.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidMeropenem suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- China, BeijingUnclaimed profileMeropenemGrade, purity and minimum order on requestPrice on request
- ChinaUnclaimed profileMeropenemGrade, purity and minimum order on requestPrice on request
- China, Hangzhou ManufacturerUnclaimed profileMeropenemGrade, purity and minimum order on requestPrice on request
- China, WuxiUnclaimed profileMeropenemGrade, purity and minimum order on requestPrice on request
- China, BeijingUnclaimed profileMeropenemGrade, purity and minimum order on requestPrice on request
- China, XinxiangUnclaimed profileMeropenemGrade, purity and minimum order on requestPrice on request
- China ManufacturerUnclaimed profileMeropenemGrade, purity and minimum order on requestPrice on request
- Price on request
- Price on request
- Italy, Albano Sant'Alessandro (BG) ManufacturerUnclaimed profileMeropenem sodium carbonateGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
72 suppliers in 13 countries
- United States26
- China24
- Germany3
- Spain3
- United Kingdom3
- India2
- and 7 more countries
Send one request to many suppliers
Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.
Meropenem price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Industries and functions
Pharmacological actions
- Anti-Bacterial Agents
Roles
- aetiopathogenetic role
- allergen
- antibacterial agent
- antibacterial drug
- antiinfective agent
- antimicrobial agent
- antimicrobial drug
- antimycobacterial drug
- antineoplastic agent
- antitubercular agent
- drug allergen
- pharmaceutical
Pharmacology
Meropenem anhydrous is a Penem Antibacterial.
How it is made
Preparation: M. Sunagawa et al., EP 126587, M. Sunagawa, US 4943569 (1984, 1990 both to Sumitomo)
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- Active ingredient in FDA approved drug labels
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Meropenem is traded under.
Antibiotics, other
- China39.7%
- United States11.3%
- Switzerland * partner reported10.9%
* Partner reported figures, a lower bound.
The HS code shown for Meropenem is indicative (it is known at chapter level only). Confirm the classification with your customs broker before shipping.
Related chemicals
Parent and salt forms, stereoisomers, similar structures and isomers
Salt and hydrate forms
Records that share this compound as their parent
![(4R,5S,6S)-3-{[(3S,5S)-5-(Dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate chemical structure, C17H27N3O6S, CAS 2456294-69-0](/s/WCDAAZJSDNCCFU-NACOAMSHSA-N.svg)
![Disodium (4R,5S,6S)-3-(((3S,5S)-5-(dimethylcarbamoyl)-3-pyrrolidinyl)thio)-4-methyl-6-((1R)-1-oxidoethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate chemical structure, C17H23N3Na2O5S, CAS 1430660-39-1](/s/IVDDFYADIXACRL-KILJLSCOSA-M.svg)
Stereoisomers and isotopic forms
Same connectivity, different stereochemistry or isotopes (same InChIKey skeleton)
Similar structures
Nearest neighbours by Morgan fingerprint Tanimoto similarity
Same formula isomers
Different compounds that share this molecular formula
![Ethyl 4-[N-(methylsulfonyl)-N-phenylalanyl]piperazine-1-carboxylate chemical structure, C17H25N3O5S, CAS 474009-96-6](/s/NUKGJMSHXBUNPF-UHFFFAOYSA-N.svg)
![N-{1-[(4-Methoxyphenyl)sulfonyl]-4-piperidinyl}-4-morpholinecarboxamide chemical structure, C17H25N3O5S, CAS 551920-86-6](/s/KDOJWCREPKVPTD-UHFFFAOYSA-N.svg)
![Ethyl 4-[N-benzyl-N-(methylsulfonyl)glycyl]-1-piperazinecarboxylate chemical structure, C17H25N3O5S, CAS 593264-22-3](/s/WBQPHPWAKVEBSO-UHFFFAOYSA-N.svg)
![t-Butyl 2-{[(1-acetyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]amino}ethylcarboxylate chemical structure, C17H25N3O5S, CAS 1427461-09-3](/s/YONPTTWUUBDESF-UHFFFAOYSA-N.svg)
![1-((3aR,4R,6R,6aR)-6-(Hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-5-(pyrrolidin-1-ylmethyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one chemical structure, C17H25N3O5S, CAS 89845-82-9](/s/IFJTVPASSJKUFD-RGCMKSIDSA-N.svg)
Frequently asked questions
Quick answers about Meropenem, based on the data on this page
What is Meropenem?
What is the CAS number of Meropenem?
What is the molecular formula and weight of Meropenem?
What is Meropenem used for?
Is Meropenem hazardous?
What is the HS code of Meropenem?
Where can I buy Meropenem?
Where can I buy Meropenem in India?
What is the price of Meropenem?
Guides for buyers
Practical guides that help when you source, ship or handle Meropenem
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
Get quotes for Meropenem
Embed this structure on your websiteShow code
Paste this code into your page to show the 2D structure of Meropenem with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.
<iframe src="https://www.compoundlist.com/embed/structure/meropenem-96036-03-2" title="Meropenem structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>Explore more in Antibiotics and anti-infectives or HS code 294190