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Key facts

What buyers check first

CAS number
223673-61-8
Formula
C21H24N4O2S
Molar mass
396.52 g/mol
EC number
800-126-3
HS code
293410
Category
Other active pharmaceutical ingredients

What is Mirabegron?

Plain description, key identifiers and synonyms

Mirabegron is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2-amino-1,3-thiazol-4-ylacetic acid with the anilino group of (1R)-2-{[2-(4-aminophenyl)ethyl]amino}-1-phenylethanol. Used for the treatment of overactive bladder syndrome. It has a role as a beta-adrenergic agonist. It is a member of ethanolamines, a monocarboxylic acid amide, a member of 1,3-thiazoles and an aromatic amide.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-(2-amino-1,3-thiazol-4-yl)-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]acetamide
CAS number
223673-61-8 CAS number cross-checked
EC number
800-126-3
Molecular formula
C21H24N4O2S
UNII
MVR3JL3B2V
MDL number
MFCD11100356
InChIKey
PBAPPPCECJKMCM-IBGZPJMESA-N
InChI
InChI=1S/C21H24N4O2S/c22-21-25-18(14-28-21)12-20(27)24-17-8-6-15(7-9-17)10-11-23-13-19(26)16-4-2-1-3-5-16/h1-9,14,19,23,26H,10-13H2,(H2,22,25)(H,24,27)/t19-/m0/s1
Canonical SMILES
Nc1nc(CC(=O)Nc2ccc(CCNCC(O)c3ccccc3)cc2)cs1
Isomeric SMILES
C1=CC=C(C=C1)[C@H](CNCCC2=CC=C(C=C2)NC(=O)CC3=CSC(=N3)N)O

Synonyms

  • Myrbetriq
  • Betanis
  • Betmiga
  • 2-(2-amino-1,3-thiazol-4-yl)-N-[4-(2-{[(2R)-2-hydroxy-2-phenylethyl]amino}ethyl)phenyl]acetamide
  • 2-(2-amino-1,3-thiazol-4-yl)-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]acetamide
  • 2-(2-Aminothiazol-4-yl)-4'-(2-((2-hydroxy-2-phenylethyl)amino)ethyl)acetanilide
  • 4-Thiazoleacetamide, 2-amino-N-(4-(2-(((2R)-2-hydroxy-2-phenylethyl)amino)ethyl)phenyl)-
  • 2-(2-Amino-1,3-thiazol-4-yl)-N-(4-(2-(((2R)-2-hydroxy-2-phenylethyl)amino)ethyl)phenyl)acetamide
  • mirabegronum
  • Myrbetriq granules
  • 2-(2-Aminothiazol-4-yl)-N-(4-(2-(((2R)-2-hydroxy-2-phenylethyl)amino)ethyl)phenyl) Acetamide
  • YM 178
  • 2-Amino-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-thiazoleacetamide
  • (R)-2-(2-aminothiazol-4-yl)-N-(4-(2-((2-hydroxy-2-phenylethyl)amino)ethyl)phenyl)acetamide
  • Mirabegron (YM178)
  • (R)-2-(2-aminothiazol-4-yl)-N-(4-(2-(2-hydroxy-2-phenylethylamino)ethyl)phenyl)acetamide
  • Myrbetriq (TN)
  • 2-(2-azanyl-1,3-thiazol-4-yl)-N-[4-[2-[[(2R)-2-oxidanyl-2-phenyl-ethyl]amino]ethyl]phenyl]ethanamide
  • Mirabegron CRS
  • Mirabegron (Standard)
  • Mirabegron racemate CRS
  • Mirabegron [EP monograph]
  • Mirabegron (JAN/USAN/INN)
  • 2-(2-aminothiazol-4-yl)-N-[4-[2-[[(2R)-2-hydroxy-2-phenyl-ethyl]amino]ethyl]phenyl]acetamide
  • (R)-2-(2-aminothiazol-4-yl)-4'-[2-[(2-hydroxy-2-phenylethyl)amino]ethyl]acetanilide
Show all 27 synonyms
  • (2R)-2-(2-Aminothiazol-4-yl)-4'-[2-[(2-hydrox y-2-phenylethyl)amino]ethyl]acetic acid anilide
  • (R)-2-(2-Amino-4-thiazolyl)-N-[4-[2-[(2-hydroxy-2-phenylethyl)amino]ethyl]phenyl]acetamide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
396.52 g/molcalc.
Exact mass
396.162 Dacalc.
LogP (octanol/water)
2.77calc.
Topological polar surface area
100.3 ร…ยฒcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
9calc.
Heavy atoms
28calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.24calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(Cc1cscn1)Nc1ccc(CCNCCc2ccccc2)cc1

O=C(Cc1cscn1)Nc1ccc(CCNCCc2ccccc2)cc1

3 rings, 26 atoms.

69 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H302Harmful if swallowed.
  • H317May cause an allergic skin reaction.
  • H319Causes serious eye irritation.
  • H361Suspected of damaging fertility or the unborn child.
  • H361dSuspected of damaging the unborn child.
  • H373May cause damage to organs through prolonged or repeated exposure.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (22)
  • P203Obtain, read and follow all safety instructions before use.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Mirabegron suppliers

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Mirabegron price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Adrenergic beta-3 Receptor Agonists
  • Urological Agents

Roles

  • adrenergic agent
  • adrenergic agonist
  • analgesic
  • beta-adrenergic agonist
  • beta-adrenergic drug
  • cardiovascular drug
  • neurotransmitter agent
  • pharmaceutical
  • protective agent
  • renal agent
  • renoprotective agent

Pharmacology

Mirabegron is a beta3-Adrenergic Agonist. The mechanism of action of mirabegron is as an Adrenergic beta3-Agonist, and Cytochrome P450 2D6 Inhibitor, and Cytochrome P450 3A Inhibitor, and P-Glycoprotein Inhibitor.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Mirabegron is traded under.

HS 2934.10Indicative HS code

Compounds containing an unfused thiazole ring (whether or not hydrogenated) in theโ€ฆ

World exports in 2024
$3.88B
โˆ’16.1% vs 2023, imports $3.12B
2019 to 2024
Top exporters
  1. Switzerland * partner reported36.4%
  2. Ireland28.8%
  3. China10.0%
Top importers
  1. Canada33.4%
  2. United States14.4%
  3. Ireland13.1%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Mirabegron is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Mirabegron, based on the data on this page

What is Mirabegron?

Mirabegron is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2-amino-1,3-thiazol-4-ylacetic acid with the anilino group of (1R)-2-{[2-(4-aminophenyl)ethyl]amino}-1-phenylethanol. Used for the treatment of overactive bladder syndrome. It has a role as a beta-adrenergic agonist.

What is the CAS number of Mirabegron?

The CAS registry number of Mirabegron is 223673-61-8.

What is the molecular formula and weight of Mirabegron?

The molecular formula of Mirabegron is C21H24N4O2S and its molar mass is 396.52 g/mol.

What is Mirabegron used for?

Known uses and roles of Mirabegron include adrenergic agent, adrenergic agonist, analgesic, beta-adrenergic agonist, beta-adrenergic drug and 8 more.

Is Mirabegron hazardous?

Mirabegron carries the GHS signal word "Warning". Main hazards: harmful if swallowed, may cause an allergic skin reaction, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Mirabegron?

Mirabegron is usually classified under HS code 293410 (Compounds containing an unfused thiazole ring (whether or not hydrogenated) in theโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Mirabegron?

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Where can I buy Mirabegron in India?

35 suppliers in India list Mirabegron on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Mirabegron?

Suppliers quote Mirabegron on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Mirabegron

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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