Moexiprilat (CAS 103775-14-0): price, suppliers and safety

What is Moexiprilat?

Plain description, key identifiers and synonyms

Moexiprilat is a non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Moexiprilat competitively inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the actions of the potent vasoconstrictor angiotensin II and leads to vasodilatation. This agent also prevents angiotensin II-induced aldosterone secretion by the adrenal cortex, thereby promoting diuresis and natriuresis.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name: (3S)-2-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
CAS number: 103775-14-0 CAS number cross-checked
Molecular formula: C₂₅H₃₀N₂O₇
UNII: H3753190JS
InChIKey: CMPAGYDKASJORH-YSSFQJQWSA-N
InChI: InChI=1S/C25H30N2O7/c1-15(26-19(24(29)30)10-9-16-7-5-4-6-8-16)23(28)27-14-18-13-22(34-3)21(33-2)12-17(18)11-20(27)25(31)32/h4-8,12-13,15,19-20,26H,9-11,14H2,1-3H3,(H,29,30)(H,31,32)/t15-,19-,20-/m0/s1
Canonical SMILES: COc1cc2c(cc1OC)CN(C(=O)C(C)NC(CCc1ccccc1)C(=O)O)C(C(=O)O)C2
Isomeric SMILES: C[C@@H](C(=O)N1CC2=CC(=C(C=C2C[C@H]1C(=O)O)OC)OC)N[C@@H](CCC3=CC=CC=C3)C(=O)O

Synonyms

moexiprilate
(3S)-2-[(2S)-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
RS 10029
moexiprilatum
(3S)-2-((2S)-2-(((2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
(3S)-2-((2S)-2-(((1S)-1-carboxy-3-phenylpropyl)amino)propanoyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
2-(2-(1-carboxy-3-phenylpropyl)amino-1-oxopropyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
Moexiprilat Hydrate
(3S)-2-((2S)-N-((1S)-1-Carboxy-3-phenylpropyl)alanyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid
(3S)-2-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
(3S)-2-((2S)-2-(((1S)-1-(Carboxy)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid
(3S)-2-{N-[(1S)-1-Carboxy-3-phenylpropyl]alanyl}-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
3-Isoquinolinecarboxylic acid, 2-((2S)-2-(((1S)-1-carboxy-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-, (3S)-
3-Isoquinolinecarboxylic acid, 2-(2-((1-(carboxy)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-, (3S-(2(r*(r*)),3r*))-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight	470.52 g/molcalc.
Exact mass	470.2053 Dacalc.
LogP (octanol/water)	2.11calc.
Topological polar surface area	125.4 Å²calc.
Hydrogen bond donors	3calc.
Hydrogen bond acceptors	6calc.
Rotatable bonds	10calc.
Heavy atoms	34calc.
Rings	3calc.
Aromatic rings	2calc.
Fraction sp3 carbons	0.4calc.
Formal charge	0calc.
Stereocentres	3calc.
Lipinski rule of five	Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

O=C(CNCCCc1ccccc1)N1CCc2ccccc2C1

3 rings, 23 atoms.

42 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Moexiprilat suppliers

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Moexiprilat price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacology

Moexiprilat is an Angiotensin Converting Enzyme Inhibitor. The mechanism of action of moexiprilat is as an Angiotensin-converting Enzyme Inhibitor.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Moexiprilat is traded under.

HS 2933.49Indicative HS code

Compounds containing in the structure a quinoline or isoquinoline ring-system (whether…

World exports in 2024

$939M

−14.6% vs 2023, imports $1.48B

2019 to 2024

Top exporters

China30.1%
India * partner reported16.7%
Switzerland * partner reported14.1%

Top importers

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Moexiprilat is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Parent and salt forms, stereoisomers, similar structures and isomers

Salt and hydrate forms

Records that share this compound as their parent

Moexiprilat hydrochloride chemical structure, C25H31ClN2O7, CAS 82586-57-0

Moexiprilat hydrochloride82586-57-0C₂₅H₃₁ClN₂O₇

Stereoisomers and isotopic forms

Same connectivity, different stereochemistry or isotopes (same InChIKey skeleton)

2-[2-[(1-Carboxy-3-phenylpropyl)amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid chemical structure, C25H30N2O7, CAS 1356840-08-8

2-[2-[(1-Carboxy-3-phenylpropyl)amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid1356840-08-8C₂₅H₃₀N₂O₇

Moexiprilat-d5 chemical structure, C25H30N2O7

Moexiprilat-d5C₂₅H₃₀N₂O₇

(S)-2-((S)-2-(((R)-1-Carboxy-3-phenylpropyl)amino)propanoyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid chemical structure, C25H30N2O7, CAS 103775-11-7

(S)-2-((S)-2-(((R)-1-Carboxy-3-phenylpropyl)amino)propanoyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid103775-11-7C₂₅H₃₀N₂O₇

(3R)-2-[(2R)-2-[[(1S)-1-Carboxy-3-phenylpropyl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid chemical structure, C25H30N2O7

(3R)-2-[(2R)-2-[[(1S)-1-Carboxy-3-phenylpropyl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acidC₂₅H₃₀N₂O₇

Similar structures

Nearest neighbours by Morgan fingerprint Tanimoto similarity

Moexipril chemical structure, C27H34N2O7, CAS 103775-10-6

Moexipril hydrochloride chemical structure, C27H35ClN2O7, CAS 82586-52-5

Quinaprilat chemical structure, C23H26N2O5, CAS 82768-85-2

Quinapril chemical structure, C25H30N2O5, CAS 85441-61-8

epi-Ethoxycarbonyl quinapril chemical structure, C25H30N2O5, CAS 103775-09-3

Quinapril hydrochloride chemical structure, C25H31ClN2O5, CAS 82586-55-8

Enalaprilat chemical structure, C18H24N2O5, CAS 76420-72-9

Same formula isomers

Different compounds that share this molecular formula

All isomers

Ici D1542 chemical structure, C25H30N2O7, CAS 147332-48-7

Ici D1542147332-48-7C₂₅H₃₀N₂O₇

5-(3,4-Diethoxyphenyl)-4-(2-furylcarbonyl)-3-hydroxy-1-(2-morpholin-4-ylethyl)-3-pyrrolin-2-one chemical structure, C25H30N2O7, CAS 619279-44-6

5-(3,4-Diethoxyphenyl)-4-(2-furylcarbonyl)-3-hydroxy-1-(2-morpholin-4-ylethyl)-3-pyrrolin-2-one619279-44-6C₂₅H₃₀N₂O₇

5-(2,5-Dimethoxyphenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-[3-(4-morpholinyl)propyl]-1,5-dihydro-2H-pyrrol-2-one chemical structure, C25H30N2O7, CAS 636990-38-0

5-(2,5-Dimethoxyphenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-[3-(4-morpholinyl)propyl]-1,5-dihydro-2H-pyrrol-2-one636990-38-0C₂₅H₃₀N₂O₇

5-(4-Ethoxy-3-methoxyphenyl)-3-hydroxy-4-[(5-methyl(2-furyl))carbonyl]-1-(2-mo rpholin-4-ylethyl)-3-pyrrolin-2-one chemical structure, C25H30N2O7, CAS 638135-47-4

5-(4-Ethoxy-3-methoxyphenyl)-3-hydroxy-4-[(5-methyl(2-furyl))carbonyl]-1-(2-mo rpholin-4-ylethyl)-3-pyrrolin-2-one638135-47-4C₂₅H₃₀N₂O₇

4'-O-Demethyl-4-((2''-(dimethylamino)ethyl)amino)-4-desoxypodophyllotoxin chemical structure, C25H30N2O7, CAS 152833-15-3

4'-O-Demethyl-4-((2''-(dimethylamino)ethyl)amino)-4-desoxypodophyllotoxin152833-15-3C₂₅H₃₀N₂O₇

3-sec-Butyl 6-methyl 2,7-dimethyl-4-(4-methyl-3-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3,6-dicarboxylate chemical structure, C25H30N2O7, CAS 1005053-19-9

3-sec-Butyl 6-methyl 2,7-dimethyl-4-(4-methyl-3-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3,6-dicarboxylate1005053-19-9C₂₅H₃₀N₂O₇

4-(2-Furylcarbonyl)-3-hydroxy-5-(3-methoxy-4-propoxyphenyl)-1-(2-morpholin-4-y lethyl)-3-pyrrolin-2-one chemical structure, C25H30N2O7, CAS 636990-50-6

4-(2-Furylcarbonyl)-3-hydroxy-5-(3-methoxy-4-propoxyphenyl)-1-(2-morpholin-4-y lethyl)-3-pyrrolin-2-one636990-50-6C₂₅H₃₀N₂O₇

N-(Fmoc-8-amino-3,6-dioxa-octyl)succinamic acid chemical structure, C25H30N2O7, CAS 613245-91-3

N-(Fmoc-8-amino-3,6-dioxa-octyl)succinamic acid613245-91-3C₂₅H₃₀N₂O₇1 supplier

1-(2-(Dimethylamino)ethyl)-3-hydroxy-4-(4-methoxybenzoyl)-5-(3,4,5-trimethoxyphenyl)-1H-pyrrol-2(5H)-one chemical structure, C25H30N2O7, CAS 384799-39-7

1-(2-(Dimethylamino)ethyl)-3-hydroxy-4-(4-methoxybenzoyl)-5-(3,4,5-trimethoxyphenyl)-1H-pyrrol-2(5H)-one384799-39-7C₂₅H₃₀N₂O₇

2-(4-Diphenylmethyl-1-piperazinyl)ethyl Acetoacetate Oxalate chemical structure, C25H30N2O7, CAS 1261268-85-2

2-(4-Diphenylmethyl-1-piperazinyl)ethyl Acetoacetate Oxalate1261268-85-2C₂₅H₃₀N₂O₇

(Z)-6-Hydroxy-7-((4-(2-hydroxyethyl)piperazin-1-yl)methyl)-2-(3,4,5-trimethoxybenzylidene)benzofuran-3(2H)-one chemical structure, C25H30N2O7, CAS 869078-47-7

(Z)-6-Hydroxy-7-((4-(2-hydroxyethyl)piperazin-1-yl)methyl)-2-(3,4,5-trimethoxybenzylidene)benzofuran-3(2H)-one869078-47-7C₂₅H₃₀N₂O₇

(4E)-1-[2-(Dimethylamino)ethyl]-4-[hydroxy(3-methoxyphenyl)methylidene]-5-(3,4,5-trimethoxyphenyl)pyrrolidine-2,3-dione chemical structure, C25H30N2O7, CAS 608503-28-2

(4E)-1-[2-(Dimethylamino)ethyl]-4-[hydroxy(3-methoxyphenyl)methylidene]-5-(3,4,5-trimethoxyphenyl)pyrrolidine-2,3-dione608503-28-2C₂₅H₃₀N₂O₇

Frequently asked questions

Quick answers about Moexiprilat, based on the data on this page

What is Moexiprilat?

Moexiprilat is a non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Moexiprilat competitively inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the actions of the potent vasoconstrictor angiotensin II and leads to vasodilatation.

What is the CAS number of Moexiprilat?

The CAS registry number of Moexiprilat is 103775-14-0.

What is the molecular formula and weight of Moexiprilat?

The molecular formula of Moexiprilat is C25H30N2O7 and its molar mass is 470.52 g/mol.

Is Moexiprilat hazardous?

No GHS hazard classification for Moexiprilat is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Moexiprilat?

Moexiprilat is usually classified under HS code 293349 (Compounds containing in the structure a quinoline or isoquinoline ring-system (whether…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Moexiprilat?

Post a free request on CompoundList and suppliers of Moexiprilat will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Moexiprilat?

Suppliers quote Moexiprilat on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Moexiprilat

Moexiprilat

Key facts

What is Moexiprilat?

Identifiers

Synonyms

Physical and chemical properties

Physical and chemical properties

Computed descriptors

Murcko scaffold

Safety and hazards

Moexiprilat suppliers

Moexiprilat price

Uses and applications

Pharmacology

Regulatory status

Health and food

HS code and trade data

Global trade

Frequently asked questions

What is Moexiprilat?

What is the CAS number of Moexiprilat?

What is the molecular formula and weight of Moexiprilat?

Is Moexiprilat hazardous?

What is the HS code of Moexiprilat?

Where can I buy Moexiprilat?

What is the price of Moexiprilat?

Guides for buyers

Get quotes for Moexiprilat

Key facts

What is Moexiprilat?

Identifiers

Synonyms

Physical and chemical properties

Physical and chemical properties

Computed descriptors

Murcko scaffold

Safety and hazards

Moexiprilat suppliers

Moexiprilat price

Uses and applications

Pharmacology

Regulatory status

Health and food

HS code and trade data

Global trade

Related chemicals

Salt and hydrate forms

Stereoisomers and isotopic forms

Similar structures

Same formula isomers

Frequently asked questions

What is Moexiprilat?

What is the CAS number of Moexiprilat?

What is the molecular formula and weight of Moexiprilat?

Is Moexiprilat hazardous?

What is the HS code of Moexiprilat?

Where can I buy Moexiprilat?

What is the price of Moexiprilat?

Guides for buyers

Get quotes for Moexiprilat