CompoundList
Sign in
Antiscalants and dispersants

Neridronate

Also known as Neridronic acid, Acido neridronico, Acide neridronique

CAS 79778-41-9Formula C6H17NO7P2Molar mass 277.15 g/molEC 635-979-9
GHS signal word: Warning. Pictograms: Harmful or irritant 4 suppliers listed
Get quotes Compare 4 suppliers
Neridronate chemical structure, C6H17NO7P2, CAS 79778-41-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
79778-41-9
Formula
C6H17NO7P2
Molar mass
277.15 g/mol
EC number
635-979-9
HS code
293149
Category
Antiscalants and dispersants

What is Neridronate?

Plain description, key identifiers and synonyms

Neridronic acid is a 1,1-bis(phosphonic acid).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(6-amino-1-hydroxy-1-phosphonohexyl)phosphonic acid
CAS number
79778-41-9 CAS number cross-checked
EC number
635-979-9
Molecular formula
C6H17NO7P2
UNII
8U27U3RIN4
MDL number
MFCD00866995
InChIKey
PUUSSSIBPPTKTP-UHFFFAOYSA-N
InChI
InChI=1S/C6H17NO7P2/c7-5-3-1-2-4-6(8,15(9,10)11)16(12,13)14/h8H,1-5,7H2,(H2,9,10,11)(H2,12,13,14)
SMILES (canonical and isomeric)
C(CCC(O)(P(=O)(O)O)P(=O)(O)O)CCN

Synonyms

  • Neridronic acid
  • Acido neridronico
  • Acide neridronique
  • AHHexBP
  • Acidum neridronicum
  • (6-Amino-1-hydroxyhexylidene)diphosphonic acid
  • Neridronate sodium hydrate
  • (6-amino-1-hydroxy-1-phosphonohexyl)phosphonic acid
  • (6-Amino-1-hydroxyhexane-1,1-diyl)diphosphonic acid
  • (6-Amino-1-hydroxyhexane-1,1-diyl)bis(phosphonic acid)
  • 6-Amino-1-hydroxyhexylidene bisphosphonic acid
  • 6-Amino-1-hydroxyhexane-1,1-diphosphonate
  • (6-amino-1-hydroxy-1-phosphono-hexyl)phosphonic acid
  • (6-Azanyl-1-Oxidanyl-1-Phosphono-Hexyl)phosphonic Acid
  • Neridronic
  • neridronic-acid
  • 79778-41-9 (free acid)
  • NRD
  • AMBTX-01
  • Phosphonic acid, (6-amino-1-hydroxyhexylidene)bis-
  • Neridronate, >=97% (NMR), solid
  • 6-aminohexane-1-hydroxy-1,1-bisphosphonate
  • 6-Hydroxy-6,6-bis-phosphono-hexyl-ammonium
  • 6-amino-1-hydroxyhexane-1,1-diyldiphosphonic acid
  • (6-Amino-1-hydroxy-1-phosphono-hexyl)-phosphonic acid
Show all 26 synonyms
  • 6-Amino-1-hydroxyhexylidene bisphosphonic acid, Neridronic acid, Nerixia

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
277.15 g/molcalc.
Exact mass
277.048 Dacalc.
LogP (octanol/water)
-0.49calc.
Topological polar surface area
161.3 Ųcalc.
Hydrogen bond donors
6calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
7calc.
Heavy atoms
16calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Neridronate suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 4 suppliers
4 of 4 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

4 suppliers in 3 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

Neridronate price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Roles

  • analgesic
  • anti-inflammatory agent
  • pharmaceutical

Pharmacology

Neridronic Acid is a third-generation, aminohexane bisphosphonate with anti-resorptive and anti-hypercalcemic activities. Although the exact mechanism of action has yet to be fully elucidated, neridronic acid binds to and adsorbs onto hydroxyapatite crystals in bone matrix, thereby preventing osteoclast resorption. This agent also binds to and inhibits farnesyl pyrophosphate synthase, an enzyme that plays an important role in the mevalonate pathway. This inhibits the formation of isoprenoids that are substrates for protein prenylation.

Read more

This prevents farnesylation and geranylgeranylation of proteins essential for osteoclast function, thereby leading to the induction of apoptosis of osteoclasts. By preventing osteoclast-mediated bone resorption, neridronic acid decreases bone turnover rate, stabilizes the bone matrix and reduces hypercalcemia.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Neridronate is traded under.

HS 2931.49Indicative HS code

Non-halogenated organo-phosphorous derivatives, other

World exports in 2024
$3.44B
−6.5% vs 2023, imports $3.07B
2022 to 2024
Top exporters
  1. China54.9%
  2. United States25.4%
  3. Germany5.1%
Top importers
  1. United States20.9%
  2. Argentina14.9%
  3. Brazil14.3%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Neridronate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Neridronate, based on the data on this page

What is Neridronate?

Neridronic acid is a 1,1-bis(phosphonic acid).

What is the CAS number of Neridronate?

The CAS registry number of Neridronate is 79778-41-9.

What is the molecular formula and weight of Neridronate?

The molecular formula of Neridronate is C6H17NO7P2 and its molar mass is 277.15 g/mol.

What is Neridronate used for?

Known uses and roles of Neridronate include scale inhibitors in water treatment, scale inhibitors in oil, gas and lubricants, analgesic, anti-inflammatory agent and pharmaceutical.

Is Neridronate hazardous?

Neridronate carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Neridronate?

Neridronate is usually classified under HS code 293149 (Non-halogenated organo-phosphorous derivatives, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Neridronate?

CompoundList lists 4 suppliers of Neridronate in China, Italy and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Neridronate?

Suppliers quote Neridronate on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Neridronate

Get quotes for Neridronate

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Neridronate
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Neridronate with a 3D view, its CAS number and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/neridronate-79778-41-9" title="Neridronate structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Antiscalants and dispersants or HS code 293149

4 suppliers
Free quotes, contact stays private
Get quotes