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Cosmetic preservatives

Oxazolidine-E

Also known as Oxazolidine E, 7-Ethylbicyclooxazolidine, 5-Ethyl-1-aza-3,7-dioxabicyclo[3.3.0]octane

CAS 7747-35-5Formula C7H13NO2Molar mass 143.19 g/molEC 231-810-4
GHS signal word: Danger. Pictograms: Corrosive, Harmful or irritant 3 suppliers listed
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Oxazolidine-E chemical structure, C7H13NO2, CAS 7747-35-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
7747-35-5
Formula
C7H13NO2
Molar mass
143.19 g/mol
EC number
231-810-4
HS code
293499
Category
Cosmetic preservatives

What is Oxazolidine-E?

Plain description, key identifiers and synonyms

Oxazolidine-E is a chemical substance with the molecular formula C7H13NO2 and a molar mass of 143.19 g/mol. Its CAS registry number is 7747-35-5. The IUPAC name is 7a-ethyl-1,3,5,7-tetrahydro-[1,3]oxazolo[3,4-c][1,3]oxazole.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
7a-ethyl-1,3,5,7-tetrahydro-[1,3]oxazolo[3,4-c][1,3]oxazole
CAS number
7747-35-5 CAS number cross-checked
EC number
231-810-4
Molecular formula
C7H13NO2
UNII
20E75SVO7A
MDL number
MFCD00192133
INCI name
7-ETHYLBICYCLOOXAZOLIDINE
InChIKey
ZRCMGIXRGFOXNT-UHFFFAOYSA-N
InChI
InChI=1S/C7H13NO2/c1-2-7-3-9-5-8(7)6-10-4-7/h2-6H2,1H3
SMILES (canonical and isomeric)
CCC12COCN1COC2

Synonyms

  • Oxazolidine E
  • 7-Ethylbicyclooxazolidine
  • 5-Ethyl-1-aza-3,7-dioxabicyclo[3.3.0]octane
  • Oxaban E
  • 7a-Ethyldihydro-1H,3H,5H-oxazolo(3,4-c)oxazole
  • 7a-ethyldihydro-1h,3h,5h-oxazolo[3,4-c]oxazole
  • Oxaban-e
  • Truptan ox-e
  • 1H,3H,5H-Oxazolo(3,4-c)oxazole, 7a-ethyldihydro-
  • AMINE CS 1246
  • 1-Aza-5-ethyl-3,7-dioxabicyclo(3.3.0)octane
  • 1H,3H,5H-Oxazolo[3,4-c]oxazole, 7a-ethyldihydro-
  • 5-ethyl-1-aza-3,7-dioxabicyclo(3.3.0)octane
  • 1H,3H,5H-Oxazolo(3,4-c)oxazone, 7a-ethyldihydro-
  • 1H,3H,5H-Oxazolo3,4-coxazole, 7a-ethyldihydro-
  • 7a-Ethyltetrahydro-1H-oxazolo[3,4-c]oxazole
  • Zoldine ZE
  • Neosyn TX
  • Chemtan A 60
  • Paramel TX 50
  • Bioban CS 1246
  • 7a-ethyl-1,3,5,7-tetrahydro-[1,3]oxazolo[3,4-c][1,3]oxazole
  • 1H,3H,5H-Oxazolo[3,4-c]oxazole,7a-ethyldihydro-
  • 7a-ethyl-tetrahydro-1H-[1,3]oxazolo[3,4-c][1,3]oxazole
  • 7a-ethyl-1,3,5,7-tetrahydrooxazolo[3,4-c]oxazole
Show all 31 synonyms
  • 7-Ethyl bicyclooxazolidine
  • 5-Ethyl-3,7-dioxa-1-azabicyclo[3.3.0]octane, Dihydro-7a-ethyloxazolo[3,4-c]oxazole
  • 5-ethyl-1-aza-3,7-dioxabicyclo [3,3,0] octane
  • 5-Ethyl-1-aza-3,7-dioxabicyclo[3.3.0]octane, 97%
  • 7-Ethylbicyclooxazolidine Solution in Methanol, 2000ug/mL
  • 7a-Ethyldihydro-1H,3H,5H-[1,3]oxazolo[3,4-c][1,3]oxazole

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
143.19 g/molcalc.
Exact mass
143.0946 Dacalc.
LogP (octanol/water)
0.41calc.
Topological polar surface area
21.7 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
1calc.
Heavy atoms
10calc.
Rings
2calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1OCN2COCC12

C1OCN2COCC12

2 rings, 8 atoms, the Dihydro-1H,3H,5H-oxazolo(3,4-C)oxazole ring system.

17 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS05: Corrosive
Corrosive
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H317May cause an allergic skin reaction.
  • H318Causes serious eye damage.
  • H319Causes serious eye irritation.
  • H332Harmful if inhaled.
  • H335May cause respiratory irritation.
  • H412Harmful to aquatic life with long lasting effects.
Precautionary statements (21)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Oxazolidine-E suppliers

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All 3 suppliers

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Where suppliers are based

3 suppliers in 2 countries

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Oxazolidine-E price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Use classes: Cosmetics.

Cosmetic ingredient, INCI name 7-ETHYLBICYCLOOXAZOLIDINE(preservative)

Functional uses

  • Biocide
  • Preservative

Cosmetic functions

  • Preservative

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory
  • EU Cosmetics Regulation Annex V, allowed preservative
    Name: 7-ETHYLBICYCLOOXAZOLIDINE, Ref no: 49, Annex ref: V/49

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Oxazolidine-E is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Oxazolidine-E is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Oxazolidine-E, based on the data on this page

What is Oxazolidine-E?

Oxazolidine-E is a chemical substance with the molecular formula C7H13NO2 and a molar mass of 143.19 g/mol. Its CAS registry number is 7747-35-5. The IUPAC name is 7a-ethyl-1,3,5,7-tetrahydro-[1,3]oxazolo[3,4-c][1,3]oxazole.

What is the CAS number of Oxazolidine-E?

The CAS registry number of Oxazolidine-E is 7747-35-5.

What is the molecular formula and weight of Oxazolidine-E?

The molecular formula of Oxazolidine-E is C7H13NO2 and its molar mass is 143.19 g/mol.

What is Oxazolidine-E used for?

Use classes: Cosmetics.

Is Oxazolidine-E hazardous?

Oxazolidine-E carries the GHS signal word "Danger". Main hazards: causes skin irritation, may cause an allergic skin reaction, causes serious eye damage. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Oxazolidine-E?

Oxazolidine-E is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Oxazolidine-E?

CompoundList lists 3 suppliers of Oxazolidine-E in United States and China. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Oxazolidine-E?

Suppliers quote Oxazolidine-E on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Oxazolidine-E

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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