Pargyline
Also known as N-Methyl-N-propargylbenzylamine, Pargylamine, Eudatin
Key facts
What buyers check first
- CAS number
- 555-57-7
- Formula
- C11H13N
- Molar mass
- 159.23 g/mol
- EC number
- 209-101-6
- HS code
- 292149
- Category
- Amines and amides
What is Pargyline?
Plain description, key identifiers and synonyms
Pargyline is an aromatic amine.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- N-benzyl-N-methylprop-2-yn-1-amine
- CAS number
- 555-57-7 CAS number cross-checked
- EC number
- 209-101-6
- Molecular formula
- C11H13N
- UNII
- 9MV14S8G3E
- MDL number
- MFCD00008576
- InChIKey
- DPWPWRLQFGFJFI-UHFFFAOYSA-N
- InChI
- InChI=1S/C11H13N/c1-3-9-12(2)10-11-7-5-4-6-8-11/h1,4-8H,9-10H2,2H3
- SMILES (canonical and isomeric)
- CN(CC#C)CC1=CC=CC=C1
Synonyms
- N-Methyl-N-propargylbenzylamine
- Pargylamine
- Eudatin
- Paragyline
- Supirdyl
- N-Methyl-N-2-propynylbenzylamine
- Pargilina
- Pargylinum
- Benzenemethanamine, N-methyl-N-2-propynyl-
- benzyl(methyl)(prop-2-yn-1-yl)amine
- Hydrochloride, Pargyline
- N-benzyl-N-methylprop-2-yn-1-amine
- Pargylin
- Benzyl-methyl-2-propinylamin
- Benzylmethylpropargylamine
- N-Benzyl-N-methyl-2-propynylamine
- N-Methyl-N-benzylpropynylamine
- MO 911
- N-Benzyl-N-methyl-2-propyn-1-amine
- Pargyline (INN)
- Pargyline chloride
- Benzylamine, N-methyl-n-2-propynyl-
- CBChromo1_000308
- N-benzyl-N-methyl-prop-2-yn-1-amine
- Pargyline (hydrochloride)
Show all 30 synonymsShow fewer synonyms
- N-methyl-N-(phenylmethyl)prop-2-yn-1-amine
- Benzyl-methyl-prop-2-ynyl-amine
- methylbenzylprop-2-ynylamine
- Eutonyl (Salt/Mix)
- Pargyline (Standard)
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 159.23 g/molcalc.Computed value |
|---|---|
| Exact mass | 159.1048 Dacalc.Computed value |
| LogP (octanol/water) | 1.75calc.Computed value |
| Topological polar surface area | 3.24 Ųcalc.Computed value |
| Hydrogen bond donors | 0calc.Computed value |
| Hydrogen bond acceptors | 1calc.Computed value |
| Rotatable bonds | 3calc.Computed value |
| Heavy atoms | 12calc.Computed value |
| Rings | 1calc.Computed value |
| Aromatic rings | 1calc.Computed value |
| Fraction sp3 carbons | 0.27calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H301Toxic if swallowed.
- H311Toxic in contact with skin.
- H315Causes skin irritation.
- H319Causes serious eye irritation.
- H331Toxic if inhaled.
- H335May cause respiratory irritation.
Precautionary statements (22)
- P261Avoid breathing dust, fume, gas, mist, vapours or spray.
- P262Do not get in eyes, on skin, or on clothing.
- P264Wash skin thoroughly after handling.
- P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
- P270Do not eat, drink or smoke when using this product.
- P271Use only outdoors or in a well-ventilated area.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P301 + P316If swallowed: Get emergency medical help immediately.
- P302 + P352If on skin: Wash with plenty of water.
- P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
- P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P316Get emergency medical help immediately.
- P319Get medical help if you feel unwell.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P330Rinse mouth.
- P332 + P317If skin irritation occurs: Get medical help.
- P337 + P317If eye irritation persists: Get medical help.
- P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P403 + P233Store in a well-ventilated place. Keep container tightly closed.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidPargyline suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- China, WuxiUnclaimed profilePargylineGrade, purity and minimum order on requestPrice on request
- Price on request
- Price on request
- United States, San DiegoUnclaimed profilePargylineGrade, purity and minimum order on requestPrice on request
- United States, San DiegoUnclaimed profilePargylineGrade, purity and minimum order on requestPrice on request
- China, NanjingUnclaimed profilePargylineGrade, purity and minimum order on requestPrice on request
- United States, Monmouth JunctionUnclaimed profilePargylineGrade, purity and minimum order on requestPrice on request
- Price on request
- Spain, BarcelonaUnclaimed profilePargylineGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
64 suppliers in 11 countries
- United States29
- China18
- United Kingdom4
- Spain3
- Germany2
- Hong Kong2
- and 5 more countries
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Pargyline price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Use classes: Nervous System.
Industries and functions
Pharmacological actions
- Antihypertensive Agents
- Monoamine Oxidase Inhibitors
Roles
- antihypertensive agent
- cardiovascular drug
- pharmaceutical
Pharmacology
Pargyline is a monoamine oxidase (MAO) inhibitor with antidepressant activity. Pargyline selectively inhibits MAO type B, an enzyme catalyzing the oxidative deamination and inactivation of certain catecholamines, such as norepinephrine and dopamine, within the presynaptic nerve terminals. By inhibiting the metabolism of these biogenic amines in the brain, pargyline increases their concentration and binding to postsynaptic receptors. Increased receptor stimulation may cause downregulation of central receptors which may attribute to pargyline's antidepressant effect.
Regulatory status
Inventories, regulations and trade controls that list this substance
No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Pargyline is traded under.
Aromatic monoamines and their derivatives, salts thereof, other
- Belgium15.9%
- South Korea15.0%
- Germany12.8%
The HS code shown for Pargyline is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Pargyline, based on the data on this page
What is Pargyline?
What is the CAS number of Pargyline?
What is the molecular formula and weight of Pargyline?
What is Pargyline used for?
Is Pargyline hazardous?
What is the HS code of Pargyline?
Where can I buy Pargyline?
What is the price of Pargyline?
Guides for buyers
Practical guides that help when you source, ship or handle Pargyline
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
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