CompoundList
Sign in
Alkaloids

Rhynchophylline

Also known as Rhyncophylline, Mitrinermine, Rhynchophyllin

CAS 76-66-4Formula C22H28N2O4Molar mass 384.48 g/molEC 683-092-0
GHS signal word: Danger. Pictograms: Acute toxicity (severe) 8 suppliers listed
Get quotes Compare 8 suppliers
Rhynchophylline chemical structure, C22H28N2O4, CAS 76-66-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
76-66-4
Formula
C22H28N2O4
Molar mass
384.48 g/mol
EC number
683-092-0
HS code
293979
Category
Alkaloids

What is Rhynchophylline?

Plain description, key identifiers and synonyms

Rhynchophylline is a member of indolizines. It has a role as a metabolite.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
methyl (E)-2-[(3R,6'R,7'S,8'aS)-6'-ethyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate
CAS number
76-66-4 CAS number cross-checkedOther or deprecated CAS: 39032-61-6
EC number
683-092-0
Molecular formula
C22H28N2O4
UNII
46BQ79VJ8D
MDL number
MFCD00221748
InChIKey
DAXYUDFNWXHGBE-KAXDATADSA-N
InChI
InChI=1S/C22H28N2O4/c1-4-14-12-24-10-9-22(17-7-5-6-8-18(17)23-21(22)26)19(24)11-15(14)16(13-27-2)20(25)28-3/h5-8,13-15,19H,4,9-12H2,1-3H3,(H,23,26)/b16-13+/t14-,15-,19-,22+/m0/s1
Canonical SMILES
CCC1CN2CCC3(C(=O)Nc4ccccc43)C2CC1C(=COC)C(=O)OC
Isomeric SMILES
CC[C@H]1CN2CC[C@]3([C@@H]2C[C@@H]1/C(=C\OC)/C(=O)OC)C4=CC=CC=C4NC3=O

Synonyms

  • Rhyncophylline
  • Mitrinermine
  • Rhynchophyllin
  • Mitrinermin
  • methyl (E)-2-[(3R,6'R,7'S,8'aS)-6'-ethyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate
  • methyl (E)-2-((1R,6R,7S,8aS)-6-ethyl-2'-oxo-spiro(3,5,6,7,8,8a-hexahydro-2H-indolizine-1,3'-indoline)-7-yl)-3-methoxy-prop-2-enoate
  • methyl (E)-2-((3R,6'R,7'S,8'aS)-6'-ethyl-2-oxospiro(1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine)-7'-yl)-3-methoxyprop-2-enoate
  • methyl (E)-2-[(1R,6R,7S,8aS)-6-ethyl-2'-oxo-spiro[3,5,6,7,8,8a-hexahydro-2H-indolizine-1,3'-indoline]-7-yl]-3-methoxy-prop-2-enoate
  • methyl (E)-2-((6'R,7'S)-6'-ethyl-2-oxospiro(1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine)-7'-yl)-3-methoxyprop-2-enoate
  • Rhynocophylline
  • Isorhychophylline
  • Corynoxan-16-carboxylic acid, 16,17-didehydro-17-methoxy-2-oxo-, methyl ester, (7-beta,16E,20-alpha)-
  • Rhynchophylline (Standard)
  • Rhynchophylline - Bio-X trade mark
  • Rhynchophylline (constituent of cat's claw)
  • Methyl (16E)-17-methoxy-2-oxo-7beta,20alpha-corynox-16-en-16-carboxylate
  • Corynoxan-16-carboxylic acid, 16,17-didehydro-17-methoxy-2-oxo-, methyl ester, (7beta,16E,20.alpha.)
  • Rel-methyl (E)-2-((3R,6'R,7'S,8a'S)-6'-ethyl-2-oxo-2',3',6',7',8',8a'-hexahydro-5'H-spiro[indoline-3,1'-indolizin]-7'-yl)-3-methoxyacrylate

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
384.48 g/molcalc.
Exact mass
384.2049 Dacalc.
LogP (octanol/water)
2.7calc.
Topological polar surface area
67.87 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
4calc.
Heavy atoms
28calc.
Rings
4calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.55calc.
Formal charge
0calc.
Stereocentres
4calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1Nc2ccccc2C12CCN1CCCCC12

O=C1Nc2ccccc2C12CCN1CCCCC12

4 rings, 18 atoms.

13 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)

Hazard statements

  • H300Fatal if swallowed.
Precautionary statements (7)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Rhynchophylline suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 8 suppliers
8 of 8 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

8 suppliers in 2 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

Rhynchophylline price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Roles

  • metabolite

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Rhynchophylline is traded under.

HS 2939.79Indicative HS code

Alkaloids of vegetal origin, other than cocaine, ecgonine, salts, esters and other derivatives, not elsewhere…

World exports in 2024
$701M
+18.9% vs 2023, imports $830M
2019 to 2024
Top exporters
  1. Switzerland * partner reported25.3%
  2. Germany21.4%
  3. India * partner reported14.9%
Top importers
  1. United States20.9%
  2. Germany14.7%
  3. Italy14.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Rhynchophylline is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Rhynchophylline, based on the data on this page

What is Rhynchophylline?

Rhynchophylline is a member of indolizines. It has a role as a metabolite.

What is the CAS number of Rhynchophylline?

The CAS registry number of Rhynchophylline is 76-66-4. Other or deprecated CAS numbers: 39032-61-6.

What is the molecular formula and weight of Rhynchophylline?

The molecular formula of Rhynchophylline is C22H28N2O4 and its molar mass is 384.48 g/mol.

What is Rhynchophylline used for?

Known uses and roles of Rhynchophylline include metabolite.

Is Rhynchophylline hazardous?

Rhynchophylline carries the GHS signal word "Danger". Main hazards: fatal if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Rhynchophylline?

Rhynchophylline is usually classified under HS code 293979 (Alkaloids, natural or reproduced by synthesis, and their salts, ethers, esters and other…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Rhynchophylline?

CompoundList lists 8 suppliers of Rhynchophylline in United States and China. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Rhynchophylline?

Suppliers quote Rhynchophylline on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Rhynchophylline

Get quotes for Rhynchophylline

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Rhynchophylline
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Rhynchophylline with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/rhynchophylline-76-66-4" title="Rhynchophylline structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Alkaloids or HS code 293979

8 suppliers
Free quotes, contact stays private
Get quotes