Selamectin
Also known as Revolution, UK-124,114, Selamectina
Key facts
What buyers check first
- CAS number
- 220119-17-5
- Formula
- C43H63NO11
- Molar mass
- 769.97 g/mol
- EC number
- 811-481-9
- HS code
- 293220
- Category
- Antibiotics and anti-infectives
What is Selamectin?
Plain description, key identifiers and synonyms
Selamectin is a milbemycin.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (1R,4S,5'S,6R,6'S,8R,10E,12S,13S,14E,16E,20R,21Z,24S)-6'-cyclohexyl-24-hydroxy-21-hydroxyimino-12-[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one
- CAS number
- 220119-17-5Other or deprecated CAS: 165108-07-6
- EC numbers
- 811-481-9, 815-979-7
- Molecular formula
- C43H63NO11
- UNII
- A2669OWX9N
- MDL number
- MFCD31621085
- InChIKey
- AFJYYKSVHJGXSN-XHKIUTQPSA-N
- InChI
- InChI=1S/C43H63NO11/c1-24-11-10-14-30-23-50-40-36(44-48)27(4)19-33(43(30,40)47)41(46)52-32-20-31(16-15-25(2)38(24)53-35-21-34(49-6)37(45)28(5)51-35)54-42(22-32)18-17-26(3)39(55-42)29-12-8-7-9-13-29/h10-11,14-15,19,24,26,28-29,31-35,37-40,45,47-48H,7-9,12-13,16-18,20-23H2,1-6H3/b11-10+,25-15+,30-14+,44-36-/t24-,26-,28-,31+,32-,33-,34-,35-,37-,38-,39-,40+,42+,43+/m0/s1
- Canonical SMILES
- COC1CC(OC2C(C)=CCC3CC(CC4(CCC(C)C(C5CCCCC5)O4)O3)OC(=O)C3C=C(C)C(=NO)C4OCC(=CC=CC2C)C34O)OC(C)C1O
- Isomeric SMILES
- C[C@H]1CC[C@]2(C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]\5[C@@]4([C@@H](C=C(/C5=N/O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O)OC)\C)O[C@@H]1C7CCCCC7
Synonyms
- Revolution
- UK-124,114
- Selamectina
- Selamectine
- 25-cyclohexyl-25-de(1-methylpropyl)-5-deoxy-22 23-dihydro-5-(hydroxyimino)-avermectin B1 monosaccharide
- Stronghold component selamectin
- Stronghold plus component selamectin
- selamectinum
- Selarid
- Revolt
- SelaSpot
- Senergy
- Avermectin A1a, 25-cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)-
- Selamectin?
- Z-Selamectin
- Selamectin CRS
- Selamectin (Standard)
- Revolution (antibiotic)
- Selamectin (USAN/INN)
- Selamectin 100 |Ig/mL in Acetonitrile
- 25-Cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)-avermectin A1a
- Selamectin 100 microg/mL in Acetonitrile
- UK 124114
- Selamectin for veterinary use [EP monograph]
- (5Z)-25-Cyclohexyl-4?-O-de(2,6-dideoxy-3-O-methyl-?-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)avermectin
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 769.97 g/molcalc.Computed value |
|---|---|
| Exact mass | 769.4401 Dacalc.Computed value |
| LogP (octanol/water) | 6.07calc.Computed value |
| Topological polar surface area | 154.7 Ųcalc.Computed value |
| Hydrogen bond donors | 3calc.Computed value |
| Hydrogen bond acceptors | 12calc.Computed value |
| Rotatable bonds | 4calc.Computed value |
| Heavy atoms | 55calc.Computed value |
| Rings | 7calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 0.77calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 14calc.Computed value |
| Lipinski rule of five | Fails (3 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
N=C1C=CC2C(=O)OC3CC(CC=CC(OC4CCCCO4)CC=CC=C4COC1C42)OC1(CCCC(C2CCCCC2)O1)C3
7 rings, 45 atoms.
16 other chemicals share this scaffoldSafety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H373May cause damage to organs through prolonged or repeated exposure.
- H400Very toxic to aquatic life.
- H410Very toxic to aquatic life with long lasting effects.
- H413May cause long lasting harmful effects to aquatic life.
Precautionary statements (5)
- P260Do not breathe dust, fume, gas, mist, vapours or spray.
- P273Avoid release to the environment.
- P319Get medical help if you feel unwell.
- P391Collect spillage.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidSelamectin suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- Hong Kong ManufacturerUnclaimed profileSelamectinGrade, purity and minimum order on requestPrice on request
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- China, ShanghaiUnclaimed profileSelamectinGrade, purity and minimum order on requestPrice on request
- China, Shanghai ManufacturerUnclaimed profileSelamectinGrade, purity and minimum order on requestPrice on request
- China, Hangzhou ManufacturerUnclaimed profileSelamectinGrade, purity and minimum order on requestPrice on request
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- China, JintanUnclaimed profileSelamectinGrade, purity and minimum order on requestPrice on request
- China, Jinhua ManufacturerUnclaimed profileSelamectinGrade, purity and minimum order on requestPrice on request
- United Kingdom, Cramlington ManufacturerUnclaimed profileSelamectinGrade, purity and minimum order on requestPrice on request
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Where suppliers are based
30 suppliers in 7 countries
- China16
- United States3
- Hong Kong2
- Australia1
- United Kingdom1
- Japan1
- and 1 more countries
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Selamectin price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Use classes: Pharmaceuticals, Animal Drugs.
Pharmacological actions
- Antiparasitic Agents
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- Active ingredient in FDA approved drug labels
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Selamectin is traded under.
Lactones
- United States14.2%
- India * partner reported13.5%
- Brazil8.5%
* Partner reported figures, a lower bound.
The HS code shown for Selamectin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Selamectin, based on the data on this page
What is Selamectin?
What is the CAS number of Selamectin?
What is the molecular formula and weight of Selamectin?
What is Selamectin used for?
Is Selamectin hazardous?
What is the HS code of Selamectin?
Where can I buy Selamectin?
What is the price of Selamectin?
Guides for buyers
Practical guides that help when you source, ship or handle Selamectin
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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