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Sweeteners

Stevioside

Also known as Steviosin, INS NO.960, (4bS,8aS)-1-hydroxy-2-isopropyl-4b,8,8-trimethyl-5,6,7,8a,9,10-hexahydrophenanthrene-3,4-dione

CAS 57817-89-7Formula C38H60O18Molar mass 804.88 g/molEC 260-975-5
GHS signal word: Warning. Pictograms: Harmful or irritant 55 suppliers listed
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Stevioside chemical structure, C38H60O18, CAS 57817-89-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
57817-89-7
Formula
C38H60O18
Molar mass
804.88 g/mol
EC number
260-975-5
HS code
293890
Category
Sweeteners

What is Stevioside?

Plain description, key identifiers and synonyms

Stevioside is a diterpene glycoside that is rubusoside in which the hydroxy group at position 2 of the allylic beta-D-glucoside has been converted to the corresponding beta-D-glucoside. It is a natural herbal sweetener that is 250-300 times sweeter than sucrose (though with a bitter aftertaste), extracted from the Stevia rebaudiana plant native to South America. It has a role as an antioxidant, a hypoglycemic agent, an antineoplastic agent, a sweetening agent, an anti-inflammatory agent and a plant metabolite. It is a beta-D-glucoside, a bridged compound, an ent-kaurane diterpenoid, a tetracyclic diterpenoid and a diterpene glycoside. It is functionally related to a rubusoside and a steviol.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1R,4S,5R,9S,10R,13S)-13-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylate
CAS number
57817-89-7 CAS number cross-checked
EC number
260-975-5
Molecular formula
C38H60O18
UNII
0YON5MXJ9P
INCI name
STEVIOSIDE
InChIKey
UEDUENGHJMELGK-HYDKPPNVSA-N
InChI
InChI=1S/C38H60O18/c1-16-11-37-9-5-20-35(2,7-4-8-36(20,3)34(50)55-32-29(49)26(46)23(43)18(13-40)52-32)21(37)6-10-38(16,15-37)56-33-30(27(47)24(44)19(14-41)53-33)54-31-28(48)25(45)22(42)17(12-39)51-31/h17-33,39-49H,1,4-15H2,2-3H3/t17-,18-,19-,20+,21+,22-,23-,24-,25+,26+,27+,28-,29-,30-,31+,32+,33+,35-,36-,37-,38+/m1/s1
Canonical SMILES
C=C1CC23CCC4C(C)(C(=O)OC5OC(CO)C(O)C(O)C5O)CCCC4(C)C2CCC1(OC1OC(CO)C(O)C(O)C1OC1OC(CO)C(O)C(O)C1O)C3
Isomeric SMILES
C[C@@]12CCC[C@@]([C@H]1CC[C@]34[C@H]2CC[C@](C3)(C(=C)C4)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)(C)C(=O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O

Synonyms

  • Steviosin
  • INS NO.960
  • (4bS,8aS)-1-hydroxy-2-isopropyl-4b,8,8-trimethyl-5,6,7,8a,9,10-hexahydrophenanthrene-3,4-dione
  • Rebaudin
  • Diterpene glycoside
  • Stevibioside
  • alpha-G-SWEET
  • (-)-Stevioside
  • Stevian 50
  • Stevioside hydrate
  • Kaur-16-en-18-oic acid,13-[(2-O-b-D-glucopyranosyl-b-D-glucopyranosyl)oxy]-,b-D-glucopyranosyl ester, (4a)-
  • 1-O-{13alpha-[(2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-18-oxo-5beta,8alpha,9beta,10alpha-kaur-16-en-18-yl}-beta-D-glucopyranose
  • 13-[(2-O-beta-D-Glucopyranosyl-alpha-D-glucopyranosyl)oxy]kaur-16-en-18-oic acid beta-D-glucopyranosyl ester
  • Eupatorin?
  • Stevin?
  • (4a)-13-[(2-O-b-D-Glucopyranosyl-b-D-glucopyranosyl)oxy]kaur-16-en-18-oic acid b-D-glucopyranosyl ester
  • Stevioside (90%)
  • Stevioside (Standard)
  • Stevioside - min 75%
  • Stevioside - min 95%
  • Stevioside - min 98%
  • 4-17-00-03618 (Beilstein Handbook Reference)
  • 13-[(2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]kaur-16-en-18-oic acid beta-D-glucopyranosyl ester
  • (4.Alpha.)-13-((2-o-beta-d-glucopyranosyl-beta-d-glucopyranosyl)oxy)kaur-16-en-18-oic acid beta-d-glucopyranosyl ester
  • (4alpha)-beta-D-Glucopyranosyl 13-((2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)kaur-16-en-18-oate
Show all 29 synonyms
  • 1-O-{(5beta,8alpha,9beta,10alpha,13alpha)-13-[(2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-18-oxokaur-16-en-18-yl}-beta-D-glucopyranose
  • 13-[(2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-kaur-16-en-18-oic acid, (4alpha)-beta-D-glucopyranosyl ester
  • Kaur-16-en-18-oic acid, 13-((2-o-beta-d-glucopyranosyl-beta-d-glucopyranosyl)oxy)-, beta-d-glucopyranosyl ester, (4.alpha.)-
  • Kaur-16-en-18-oic acid, 13-((2-O-beta-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy)-, beta-D-glucopyranosyl ester

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
804.88 g/molcalc.
Exact mass
804.378 Dacalc.
LogP (octanol/water)
-2.94calc.
Topological polar surface area
295 Ųcalc.
Hydrogen bond donors
11calc.
Hydrogen bond acceptors
18calc.
Rotatable bonds
9calc.
Heavy atoms
56calc.
Rings
7calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.92calc.
Formal charge
0calc.
Stereocentres
21calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C=C1CC23CCC4C(C(=O)OC5CCCCO5)CCCC4C2CCC1(OC1OCCCC1OC1CCCCO1)C3

C=C1CC23CCC4C(C(=O)OC5CCCCO5)CCCC4C2CCC1(OC1OCCCC1OC1CCCCO1)C3

7 rings, 40 atoms.

4 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H317May cause an allergic skin reaction.
  • H319Causes serious eye irritation.
Precautionary statements (13)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Stevioside suppliers

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All 55 suppliers
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Where suppliers are based

55 suppliers in 9 countries

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Stevioside price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Use classes: Cosmetics.

Cosmetic ingredient, INCI name STEVIOSIDE(fragrance, oral care)

Pharmacological actions

  • Sweetening Agents

Roles

  • additive
  • anti-inflammatory agent
  • antineoplastic agent
  • antioxidant
  • eukaryotic metabolite
  • flavouring agent
  • food additive
  • food component
  • hypoglycemic agent
  • metabolite
  • pharmaceutical
  • physiological role
  • plant metabolite
  • sweetening agent

Functional uses

  • Deodorizer
  • Flavouring and nutrient

Cosmetic functions

  • Fragrance
  • Oral care

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Stevioside is traded under.

HS 2938.90Indicative HS code

Natural or reproduced by synthesis, other than rutoside (rutin) and its derivatives

World exports in 2024
$1.4B
−8.3% vs 2023, imports $1.35B
2019 to 2024
Top exporters
  1. China49.2%
  2. France * partner reported8.9%
  3. Malaysia6.1%
Top importers
  1. United States22.3%
  2. India * partner reported7.8%
  3. Brazil5.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Stevioside is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Stevioside, based on the data on this page

What is Stevioside?

Stevioside is a diterpene glycoside that is rubusoside in which the hydroxy group at position 2 of the allylic beta-D-glucoside has been converted to the corresponding beta-D-glucoside.

What is the CAS number of Stevioside?

The CAS registry number of Stevioside is 57817-89-7.

What is the molecular formula and weight of Stevioside?

The molecular formula of Stevioside is C38H60O18 and its molar mass is 804.88 g/mol.

What is Stevioside used for?

Use classes: Cosmetics.

Is Stevioside hazardous?

Stevioside carries the GHS signal word "Warning". Main hazards: causes skin irritation, may cause an allergic skin reaction, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Stevioside?

Stevioside is usually classified under HS code 293890 (Glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Stevioside?

CompoundList lists 55 suppliers of Stevioside in China, United States, India, Belgium and 5 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Stevioside in India?

2 suppliers in India list Stevioside on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Stevioside?

Suppliers quote Stevioside on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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