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Amines and amides

Sulfanilamide

Also known as 4-Aminobenzenesulfonamide, Sulphanilamide, Sulfamine

CAS 63-74-1Formula C6H8N2O2SMolar mass 172.21 g/molEC 200-563-4
GHS signal word: Warning. Pictograms: Harmful or irritant 130 suppliers listed
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Sulfanilamide chemical structure, C6H8N2O2S, CAS 63-74-1
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Leaflets from aq alcohol
Melting point
165.5 °C
Density
1.08 @ 25 °C
Solubility
IN WATER: 7.5 G/L AT 25 °C & 477 G/L AT 100 °C
HS code
293590
Category
Amines and amides
UN number
UN 1759
Illustrative photo, closed jumbo bulk bags in a warehouse in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Sulfanilamide?

Plain description, key identifiers and synonyms

Sulfanilamide is a sulfonamide in which the sulfamoyl functional group is attached to aniline at the 4-position. It has a role as an EC 4.2.1.1 (carbonic anhydrase) inhibitor, an antibacterial agent and a drug allergen. It is a sulfonamide, a substituted aniline and a sulfonamide antibiotic.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-aminobenzenesulfonamide
CAS number
63-74-1 CAS number cross-checked
EC number
200-563-4
Molecular formula
C6H8N2O2S
UNII
21240MF57M
MDL number
MFCD00007939
InChIKey
FDDDEECHVMSUSB-UHFFFAOYSA-N
InChI
InChI=1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)
SMILES (canonical and isomeric)
C1=CC(=CC=C1N)S(=O)(=O)N

Synonyms

  • 4-Aminobenzenesulfonamide
  • Sulphanilamide
  • Sulfamine
  • p-Aminobenzenesulfonamide
  • Sulfonamide
  • Sulphonamide
  • Prontylin
  • Sulfonylamide
  • Bacteramid
  • Prontosil Album
  • Prontosil I
  • Estreptocida
  • p-Aminobenzenesulfamide
  • Streptasol
  • Streptocid
  • p-Sulfamoylaniline
  • 4-Sulfamoylaniline
  • Sulfonamide P
  • Benzenesulfonamide, 4-amino-
  • 4-Aminobenzene-1-Sulfonamide
  • Antistrept
  • Astreptine
  • Collomide
  • Colsulanyde
  • Copticide
Show all 39 synonyms
  • Ergaseptine
  • Exoseptoplix
  • Gombardol
  • Neococcyl
  • Orgaseptine
  • Prontalbin
  • Proseptal
  • Septoplex
  • Septoplix
  • Streptoclase
  • Sulfamidyl
  • Sulfanalone
  • Sulfanidyl
  • Sulfocidine

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Leaflets from aq alcoholexp.
Melting point
165.5 °Cexp.
Density
1.08 @ 25 °Cexp.
Solubility
IN WATER: 7.5 G/L AT 25 °C & 477 G/L AT 100 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
172.21 g/molcalc.
Exact mass
172.0306 Dacalc.
LogP (octanol/water)
-0.08calc.
Topological polar surface area
86.18 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
1calc.
Heavy atoms
11calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 1759

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Sulfanilamide suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 130 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

130 suppliers in 22 countries

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Sulfanilamide price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Antibacterial and antimicrobial.

Veterinary medication:.

Use classes: Pharmaceuticals, Pesticide transformation products.

Pharmacological actions

  • Anti-Bacterial Agents

Roles

  • aetiopathogenetic role
  • allergen
  • antibacterial agent
  • antimicrobial agent
  • drug allergen
  • enzyme inhibitor
  • pharmaceutical

Pharmacology

Sulfanilamide is an organic sulfur compound structurally similar to p-aminobenzoic acid (PABA) with antibacterial property. Sulfanilamide competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death.

How it is made

Action of ammonia on acetylsulfanilyl chloride, followed by hydrolyzing the resulting n-acetylsulfanilamide to sulfanilamide by boiling with dilute hydrochloric acid or alkali

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Sulfanilamide is traded under.

HS 2935.90Indicative HS code

Sulphonamides, other

World exports in 2024
$5.64B
−11.0% vs 2023, imports $8.56B
2019 to 2024
Top exporters
  1. Ireland43.1%
  2. China12.0%
  3. India * partner reported9.5%
Top importers
  1. United States23.6%
  2. Slovenia19.1%
  3. Spain11.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Sulfanilamide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Sulfanilamide, based on the data on this page

What is Sulfanilamide?

Sulfanilamide is a sulfonamide in which the sulfamoyl functional group is attached to aniline at the 4-position. It has a role as an EC 4.2.1.1 (carbonic anhydrase) inhibitor, an antibacterial agent and a drug allergen. It is a sulfonamide, a substituted aniline and a sulfonamide antibiotic.

What is the CAS number of Sulfanilamide?

The CAS registry number of Sulfanilamide is 63-74-1.

What is the molecular formula and weight of Sulfanilamide?

The molecular formula of Sulfanilamide is C6H8N2O2S and its molar mass is 172.21 g/mol.

What is Sulfanilamide used for?

Antibacterial and antimicrobial. Veterinary medication:. Use classes: Pharmaceuticals, Pesticide transformation products.

Is Sulfanilamide hazardous?

Sulfanilamide carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Sulfanilamide?

Sulfanilamide is usually classified under HS code 293590 (Sulphonamides, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Sulfanilamide?

CompoundList lists 130 suppliers of Sulfanilamide in China, United States, India, Germany and 18 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Sulfanilamide in India?

13 suppliers in India list Sulfanilamide on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Sulfanilamide?

Suppliers quote Sulfanilamide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Sulfanilamide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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