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Antibiotics and anti-infectives

Sulfaquinoxaline

Also known as Sulfabenzpyrazine, Avicocid, Sulfaline

CAS 59-40-5Formula C14H12N4O2SMolar mass 300.34 g/molEC 200-423-2
GHS signal word: Danger. Pictograms: Harmful or irritant, Serious health hazard 52 suppliers listed Drug substance
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Sulfaquinoxaline chemical structure, C14H12N4O2S, CAS 59-40-5
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Minute crystals
Melting point
247.5 °C
Solubility
Mol wt: 322.32. Very sol in water, pH of 1% aqueous solution is about 10. The amorphous…
HS code
293590
Category
Antibiotics and anti-infectives
Illustrative photo, drums, an IBC tote and sacks in a chemical warehouse in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Sulfaquinoxaline?

Plain description, key identifiers and synonyms

4-amino-N-(2-quinoxalinyl)benzenesulfonamide is a member of benzenes and a sulfonamide.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-amino-N-quinoxalin-2-ylbenzenesulfonamide
CAS number
59-40-5 CAS number cross-checked
EC number
200-423-2
Molecular formula
C14H12N4O2S
UNII
WNW8115TM9
MDL number
MFCD00055406
InChIKey
NHZLNPMOSADWGC-UHFFFAOYSA-N
InChI
InChI=1S/C14H12N4O2S/c15-10-5-7-11(8-6-10)21(19,20)18-14-9-16-12-3-1-2-4-13(12)17-14/h1-9H,15H2,(H,17,18)
SMILES (canonical and isomeric)
C1=CC=C2C(=C1)N=CC(=N2)NS(=O)(=O)C3=CC=C(C=C3)N

Synonyms

  • Sulfabenzpyrazine
  • Avicocid
  • Sulfaline
  • Sulquin
  • Italquina
  • Kokozigal
  • Ursokoxaline
  • Sulfacox
  • Sulfachinoxalin
  • Sulfaquinoxalina
  • 2-Sulfanilamidoquinoxaline
  • Sulfaquinoxalinum
  • Benzenesulfonamide, 4-amino-N-2-quinoxalinyl-
  • SQ 40
  • Sul-q-nox
  • 4-Amino-N-(quinoxalin-2-yl)benzene-1-sulfonamide
  • 4-Amino-N-2-quinoxalinylbenzenesulfonamide
  • 25 % S.Q. Soluble
  • 20% Sulfaquinoxaline Sodium Solution
  • S.Q. 40%
  • Sulphaquinoxaline
  • 4-Amino-N-(quinoxalin-2-yl)benzenesulfonamide
  • Sulfa-Q 20
  • Compound 3-120
  • 2-Sulfanilamidobenzopyrazine
Show all 38 synonyms
  • Anti-K
  • 2-(p-Sulfanilamido)quinoxaline
  • Sulfaquinoxalin
  • N-(2-Quinoxalinyl)sulfanilamide
  • 4-amino-N-quinoxalin-2-ylbenzenesulfonamide
  • N1-(2-Quinoxalinyl)sulfanilamide
  • N'-2-Quinoxalylsulfanilamide
  • 2-p-Aminobenzenesulfonamidoquinoxaline
  • N-(2-Quinoxalinyl)sulfanilide
  • 4-amino-N-(2-quinoxalinyl)benzenesulfonamide
  • 2-p-Aminobenzenesulphonamidoquinoxaline
  • SQX
  • N(sup 1)-2-Quinoxalinylsulfanilamide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Minute crystalsexp.
Melting point
247.5 °Cexp.
Solubility
Mol wt: 322.32. Very sol in water, pH of 1% aqueous solution is about 10. The amorphous salt is deliquescent and absorbs carbon dioxide which liberates the practically insoluble sulfaquinoxaline /Sodium salt/exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
300.34 g/molcalc.
Exact mass
300.0681 Dacalc.
LogP (octanol/water)
2.01calc.
Topological polar surface area
97.97 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
3calc.
Heavy atoms
21calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=S(=O)(Nc1cnc2ccccc2n1)c1ccccc1

O=S(=O)(Nc1cnc2ccccc2n1)c1ccccc1

3 rings, 20 atoms.

91 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H302Harmful if swallowed.
  • H317May cause an allergic skin reaction.
  • H334May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary statements (19)
  • P233Keep container tightly closed.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P342 + P316If experiencing respiratory symptoms: Get emergency medical help immediately.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403Store in a well-ventilated place.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Sulfaquinoxaline suppliers

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All 52 suppliers
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Where suppliers are based

52 suppliers in 13 countries

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Sulfaquinoxaline price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Mesh Heading: anti-infective agents, Antiprotozoal agents.

Veterinary medication:.

/SRP67: FORMER USE IN USA/ Bactericide. Kills vitamin K-producing bacteria in the digestive system of rodents, and thereby prevents recovery of rats and mice after ingestion of substances which inhibit blood-coagulation. Used with warfarin for controlling rats and mice.

Treatment of coccidiosis in chickens, turkeys, and cattle.

Use classes: Pharmaceuticals, Animal Drugs.

Pharmacological actions

  • Anti-Infective Agents
  • Antiprotozoal Agents

Pharmacology

Sulfaquinoxaline is a sulfonamide antibiotic used in veterinary medicine and in the meat and poultry industries.

How it is made

Prepared by treating 2-aminoquinoxaline with acetylsulfanilyl chloride in the presence of pyridine and hydrolyzing the resulting acetyl derivative. US patent 2404199 (1946 to Merck and Co.)

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

United States

  • TSCA inventory (USA)
    Status: Inactive in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Sulfaquinoxaline is traded under.

HS 2935.90Indicative HS code

Sulphonamides, other

World exports in 2024
$5.64B
−11.0% vs 2023, imports $8.56B
2019 to 2024
Top exporters
  1. Ireland43.1%
  2. China12.0%
  3. India * partner reported9.5%
Top importers
  1. United States23.6%
  2. Slovenia19.1%
  3. Spain11.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Sulfaquinoxaline is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Sulfaquinoxaline, based on the data on this page

What is Sulfaquinoxaline?

4-amino-N-(2-quinoxalinyl)benzenesulfonamide is a member of benzenes and a sulfonamide.

What is the CAS number of Sulfaquinoxaline?

The CAS registry number of Sulfaquinoxaline is 59-40-5.

What is the molecular formula and weight of Sulfaquinoxaline?

The molecular formula of Sulfaquinoxaline is C14H12N4O2S and its molar mass is 300.34 g/mol.

What is Sulfaquinoxaline used for?

Mesh Heading: anti-infective agents, Antiprotozoal agents. Veterinary medication:. /SRP67: FORMER USE IN USA/ Bactericide. Kills vitamin K-producing bacteria in the digestive system of rodents, and thereby prevents recovery of rats and mice after ingestion of substances which inhibit blood-coagulation.

Is Sulfaquinoxaline hazardous?

Sulfaquinoxaline carries the GHS signal word "Danger". Main hazards: harmful if swallowed, may cause an allergic skin reaction, may cause allergy or asthma symptoms or breathing difficulties if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Sulfaquinoxaline?

Sulfaquinoxaline is usually classified under HS code 293590 (Sulphonamides, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Sulfaquinoxaline?

CompoundList lists 52 suppliers of Sulfaquinoxaline in China, United States, United Kingdom, Hong Kong and 9 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Sulfaquinoxaline in India?

2 suppliers in India list Sulfaquinoxaline on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Sulfaquinoxaline?

Suppliers quote Sulfaquinoxaline on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Sulfaquinoxaline

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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