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Analgesics and anti-inflammatories

Suprofen

Also known as Sutoprofen, Profenal, p-2-Thenoylhydratropic acid

CAS 40828-46-4Formula C14H12O3SMolar mass 260.31 g/molEC 255-096-9
GHS signal word: Danger. Pictograms: Acute toxicity (severe) 21 suppliers listed
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Suprofen chemical structure, C14H12O3S, CAS 40828-46-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
40828-46-4
Formula
C14H12O3S
Molar mass
260.31 g/mol
EC number
255-096-9
HS code
293499
Category
Analgesics and anti-inflammatories

What is Suprofen?

Plain description, key identifiers and synonyms

Suprofen is an aromatic ketone that is thiophene substituted at C-2 by a 4-(1-carboxyethyl)benzoyl group. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor, an antirheumatic drug, a peripheral nervous system drug and a drug allergen. It is a monocarboxylic acid, a member of thiophenes and an aromatic ketone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid
CAS number
40828-46-4 CAS number cross-checked
EC number
255-096-9
Molecular formula
C14H12O3S
UNII
988GU2F9PE
MDL number
MFCD00079572
InChIKey
MDKGKXOCJGEUJW-UHFFFAOYSA-N
InChI
InChI=1S/C14H12O3S/c1-9(14(16)17)10-4-6-11(7-5-10)13(15)12-3-2-8-18-12/h2-9H,1H3,(H,16,17)
SMILES (canonical and isomeric)
CC(C1=CC=C(C=C1)C(=O)C2=CC=CS2)C(=O)O

Synonyms

  • Sutoprofen
  • Profenal
  • p-2-Thenoylhydratropic acid
  • Sulproltin
  • Srendam
  • Suprofene
  • Topalgic
  • Suprofenum
  • racemic suprofen
  • 2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid
  • 4-(2-Thenoyl)hydratropsaeure
  • p-(2-thenoyl)hydratropic acid
  • TN 762
  • 2-(4-(thiophene-2-carbonyl)phenyl)propanoic acid
  • 2-(4-(2-Thenoyl)phenyl)propionsaeure
  • alpha-Methyl-4-(2-thienylcarbonyl)benzeneacetic acid
  • (+-)-2-(p-(2-Thenoyl)phenyl)propionic acid
  • Suprofeno
  • Benzeneacetic acid, alpha-methyl-4-(2-thienylcarbonyl)-
  • 2-(4-(Thiophene-2-carbonyl)-phenyl)-propionic acid
  • 2-(4-((thiophen-2-yl)carbonyl)phenyl)propanoic acid
  • 2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid
  • 2-{4-[(thiophen-2-yl)carbonyl]phenyl}propanoic acid
  • Maldocil
  • Masterfen
Show all 33 synonyms
  • Suprol
  • Suprocil
  • Suprofen (Profenal)
  • Hydratropic acid, p-(2-thenoyl)-
  • 4-(2-Thenoyl)hydratropic acid
  • 2-[4-(thiophen-2-ylcarbonyl)phenyl]propanoic acid
  • Suprofene (INN-French)
  • Suprofen (usp-rs)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
260.31 g/molcalc.
Exact mass
260.0507 Dacalc.
LogP (octanol/water)
3.17calc.
Topological polar surface area
54.37 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
4calc.
Heavy atoms
18calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.14calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(c1ccccc1)c1cccs1

O=C(c1ccccc1)c1cccs1

2 rings, 13 atoms, the 2-Benzoylthiophene ring system.

272 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)

Hazard statements

  • H301Toxic if swallowed.
Precautionary statements (7)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Suprofen suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 21 suppliers
21 of 21 offers
  • Abmole Bioscience Inc.
    United States, HoustonUnclaimed profile
    SuprofenGrade, purity and minimum order on request
    Price on request
    View
  • AChemBlock
    United States, HaywardUnclaimed profile
    SuprofenGrade, purity and minimum order on request
    Price on request
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  • ACTIVATE SCIENTIFIC GmbH
    GermanyUnclaimed profile
    SuprofenGrade, purity and minimum order on request
    Price on request
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  • Ambeed, Inc.
    United States, Buffalo GroveUnclaimed profile
    SuprofenGrade, purity and minimum order on request
    Price on request
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  • Ambinter
    France, OrleansUnclaimed profile
    SuprofenGrade, purity and minimum order on request
    Price on request
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  • BioCrick
    China, ChengduUnclaimed profile
    SuprofenGrade, purity and minimum order on request
    Price on request
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  • ChemShuttle
    United States, BurlingameUnclaimed profile
    SuprofenGrade, purity and minimum order on request
    Price on request
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  • Clearsynth
    United States, San DiegoUnclaimed profile
    SuprofenGrade, purity and minimum order on request
    Price on request
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  • Cooke Chemical Co., Ltd.
    China, FuxinUnclaimed profile
    SuprofenGrade, purity and minimum order on request
    Price on request
    View
  • DC Chemicals
    China, PudongUnclaimed profile
    SuprofenGrade, purity and minimum order on request
    Price on request
    View

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

21 suppliers in 6 countries

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Suprofen price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Anti-Inflammatory Agents, Non-Steroidal
  • Cyclooxygenase Inhibitors

Roles

  • aetiopathogenetic role
  • allergen
  • analgesic
  • anti-inflammatory agent
  • anti-inflammatory drug
  • antirheumatic drug
  • drug allergen
  • enzyme inhibitor
  • non-narcotic analgesic
  • non-steroidal anti-inflammatory drug
  • peripheral nervous system drug
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Suprofen is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Suprofen is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Suprofen, based on the data on this page

What is Suprofen?

Suprofen is an aromatic ketone that is thiophene substituted at C-2 by a 4-(1-carboxyethyl)benzoyl group.

What is the CAS number of Suprofen?

The CAS registry number of Suprofen is 40828-46-4.

What is the molecular formula and weight of Suprofen?

The molecular formula of Suprofen is C14H12O3S and its molar mass is 260.31 g/mol.

What is Suprofen used for?

Use classes: Pharmaceuticals.

Is Suprofen hazardous?

Suprofen carries the GHS signal word "Danger". Main hazards: toxic if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Suprofen?

Suprofen is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Suprofen?

CompoundList lists 21 suppliers of Suprofen in United States, China, Germany, France and 2 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Suprofen?

Suppliers quote Suprofen on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Suprofen

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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