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Antibiotics and anti-infectives

Telaprevir

Also known as Incivek, Incivo, VX 950

CAS 402957-28-2Formula C36H53N7O6Molar mass 679.86 g/molEC 609-814-6
GHS signal word: Warning. Pictograms: Harmful or irritant 46 suppliers listed
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Telaprevir chemical structure, C36H53N7O6, CAS 402957-28-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
402957-28-2
Formula
C36H53N7O6
Appearance
White to off-white powder
Solubility
In water, 0.0047 mg/mL
HS code
293399
Category
Antibiotics and anti-infectives
Illustrative photo, a white jumbo bulk bag of powder in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Telaprevir?

Plain description, key identifiers and synonyms

Telaprevir is an oligopeptide consisting of N-(pyrazin-2-ylcarbonyl)cyclohexylalanyl, 3-methylvalyl, octahydrocyclopenta[c]pyrrole-1-carboxy, and 3-amino-N-cyclopropyl-2-oxohexanamide residues joined in sequence. Used for treatment of chronic hepatitis C virus genotype 1 infection. It has a role as an antiviral drug, a peptidomimetic and a hepatitis C protease inhibitor. It is an oligopeptide, a cyclopentapyrrole, a member of pyrazines and a member of cyclopropanes.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(3S,3aS,6aR)-2-[(2S)-2-[[(2S)-2-cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoyl]-N-[(3S)-1-(cyclopropylamino)-1,2-dioxohexan-3-yl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-3-carboxamide
CAS number
402957-28-2 CAS number cross-checked
EC number
609-814-6
Molecular formula
C36H53N7O6
UNII
655M5O3W0U
MDL number
MFCD11616089
InChIKey
BBAWEDCPNXPBQM-GDEBMMAJSA-N
InChI
InChI=1S/C36H53N7O6/c1-5-10-25(29(44)34(48)39-23-15-16-23)40-33(47)28-24-14-9-13-22(24)20-43(28)35(49)30(36(2,3)4)42-32(46)27(21-11-7-6-8-12-21)41-31(45)26-19-37-17-18-38-26/h17-19,21-25,27-28,30H,5-16,20H2,1-4H3,(H,39,48)(H,40,47)(H,41,45)(H,42,46)/t22-,24-,25-,27-,28-,30+/m0/s1
Canonical SMILES
CCCC(NC(=O)C1C2CCCC2CN1C(=O)C(NC(=O)C(NC(=O)c1cnccn1)C1CCCCC1)C(C)(C)C)C(=O)C(=O)NC1CC1
Isomeric SMILES
CCC[C@@H](C(=O)C(=O)NC1CC1)NC(=O)[C@@H]2[C@H]3CCC[C@H]3CN2C(=O)[C@H](C(C)(C)C)NC(=O)[C@H](C4CCCCC4)NC(=O)C5=NC=CN=C5

Synonyms

  • Incivek
  • Incivo
  • VX 950
  • MP 424
  • VRT 111950
  • VX950 cpd
  • LY 570310
  • telaprevirum
  • Telavic
  • Telaprevir (VX-950)
  • S-Telaprevir
  • Incivek(TM)
  • Incivek (TN)
  • Incivo (TN)
  • Telaprevir,VX-950
  • VX-950 (Telaprevir)
  • Telaprevir (VX-950)?
  • Telaprevir (JAN/USAN/INN)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
White to off-white powderexp.
Solubility
In water, 0.0047 mg/mLexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
679.86 g/molcalc.
Exact mass
679.4057 Dacalc.
LogP (octanol/water)
2.45calc.
Topological polar surface area
179.6 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
8calc.
Rotatable bonds
13calc.
Heavy atoms
49calc.
Rings
5calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.72calc.
Formal charge
0calc.
Stereocentres
6calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(CNC(=O)C1C2CCCC2CN1C(=O)CNC(=O)C(NC(=O)c1cnccn1)C1CCCCC1)C(=O)NC1CC1

O=C(CNC(=O)C1C2CCCC2CN1C(=O)CNC(=O)C(NC(=O)c1cnccn1)C1CCCCC1)C(=O)NC1CC1

5 rings, 42 atoms.

9 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Telaprevir suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 46 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

46 suppliers in 9 countries

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Telaprevir price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Antiviral against hepatitis C.

Industries and functions

Roles

  • anti-HIV agent
  • antiinfective agent
  • antimicrobial agent
  • antimicrobial drug
  • antiviral agent
  • antiviral drug
  • enzyme inhibitor
  • hepatitis C protease inhibitor
  • peptidomimetic
  • pharmaceutical
  • protease inhibitor

Pharmacology

Telaprevir is a Hepatitis C Virus NS3/4A Protease Inhibitor. The mechanism of action of telaprevir is as a HCV NS3/4A Protease Inhibitor, and Cytochrome P450 3A Inhibitor, and P-Glycoprotein Inhibitor, and Organic Anion Transporting Polypeptide 1B1 Inhibitor, and Organic Anion Transporting Polypeptide 2B1 Inhibitor.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Telaprevir is traded under.

HS 2933.99Indicative HS code

Heterocyclic compounds with nitrogen hetero-atom(s) only, other

World exports in 2024
$12.1B
−31.0% vs 2023, imports $28.8B
2019 to 2024
Top exporters
  1. China30.5%
  2. India * partner reported16.3%
  3. Ireland9.0%
Top importers
  1. Slovenia31.7%
  2. Italy24.2%
  3. United States5.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Telaprevir is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Telaprevir, based on the data on this page

What is Telaprevir?

Telaprevir is an oligopeptide consisting of N-(pyrazin-2-ylcarbonyl)cyclohexylalanyl, 3-methylvalyl, octahydrocyclopenta[c]pyrrole-1-carboxy, and 3-amino-N-cyclopropyl-2-oxohexanamide residues joined in sequence. Used for treatment of chronic hepatitis C virus genotype 1 infection.

What is the CAS number of Telaprevir?

The CAS registry number of Telaprevir is 402957-28-2.

What is the molecular formula and weight of Telaprevir?

The molecular formula of Telaprevir is C36H53N7O6 and its molar mass is 679.86 g/mol.

What is Telaprevir used for?

Antiviral against hepatitis C.

Is Telaprevir hazardous?

Telaprevir carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Telaprevir?

Telaprevir is usually classified under HS code 293399 (Heterocyclic compounds with nitrogen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Telaprevir?

CompoundList lists 46 suppliers of Telaprevir in China, United States, Germany, Spain and 5 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Telaprevir in India?

2 suppliers in India list Telaprevir on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Telaprevir?

Suppliers quote Telaprevir on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Telaprevir

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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