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Tepoxalin chemical structure, C20H20ClN3O3, CAS 103475-41-8
2D chemical structure

Key facts

What buyers check first

CAS number
103475-41-8
Formula
C20H20ClN3O3
Molar mass
385.85 g/mol
EC number
638-877-2
HS code
293319
Category
Analgesics and anti-inflammatories

What is Tepoxalin?

Plain description, key identifiers and synonyms

Tepoxalin is a hydroxamic acid obtained by formal condensation of the carboxy group of 3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl]propanoic acid with the amino group of N-methylhydroxylamine. It is used in veterinary medicine for the control of pain and inflammation caused by musculoskeletal disorders such as hip dysplasia and arthritis in dogs. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, an antipyretic, an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor, a lipoxygenase inhibitor, an immunomodulator and an apoptosis inhibitor. It is a hydroxamic acid, a member of pyrazoles, an aromatic ether and a member of monochlorobenzenes.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl]-N-hydroxy-N-methylpropanamide
CAS number
103475-41-8 CAS number cross-checked
EC number
638-877-2
Molecular formula
C20H20ClN3O3
UNII
TZ4OX61974
MDL number
MFCD00866620
InChIKey
XYKWNRUXCOIMFZ-UHFFFAOYSA-N
InChI
InChI=1S/C20H20ClN3O3/c1-23(26)20(25)12-7-16-13-19(14-3-5-15(21)6-4-14)24(22-16)17-8-10-18(27-2)11-9-17/h3-6,8-11,13,26H,7,12H2,1-2H3
SMILES (canonical and isomeric)
CN(C(=O)CCC1=NN(C(=C1)C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)OC)O

Synonyms

  • Tepoxaline
  • Zubrin
  • ORF 20485
  • Tepoxalina
  • RWJ 20485
  • Tepoxalinum
  • 5-(4-Chlorophenyl)-N-hydroxy-1-(4-methoxyphenyl)-N-methyl-1H-pyrazole-3-propanamide
  • 5-(p-Chlorophenyl)-1-(p-methoxyphenyl)-N-methylpyrazole-3-propionohydroxamic acid
  • 1H-Pyrazole-3-propanamide, 5-(4-chlorophenyl)-N-hydroxy-1-(4-methoxyphenyl)-N-methyl-
  • 3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl]-N-hydroxy-N-methylpropanamide
  • Zubrin Rapidly-Disintegrating Tablets
  • 3-(5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl)-N-hydroxy-N-methylpropanamide
  • Tepoxalin (USAN/INN)
  • 3-(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-1H-pyrazol-3-yl)-N-hydroxy-N-methylpropanamide
  • 3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)-1H-pyrazol-3-yl]-N-hydroxy-N-methylpropanamide
  • 3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl]-N-hydroxy-N-methyl-propanamide
  • C20H20ClN3O3
  • tepoxaliume
  • 3-(5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-pyrazolyl)-N-hydroxy-N-methylpropanamide
  • Tepoxalin Solution in Methanol, 100ug/mL
  • 3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyrazol-3-yl]-N-hydroxy-N-methyl-propionamide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
385.85 g/molcalc.
Exact mass
385.1193 Dacalc.
LogP (octanol/water)
3.98calc.
Topological polar surface area
67.59 ร…ยฒcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
6calc.
Heavy atoms
27calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.2calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(-c2ccnn2-c2ccccc2)cc1

c1ccc(-c2ccnn2-c2ccccc2)cc1

3 rings, 17 atoms, the 1,5-Diphenyl-1H-pyrazole ring system.

451 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Tepoxalin suppliers

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All 5 suppliers
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Where suppliers are based

5 suppliers in 2 countries

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Tepoxalin price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Animal Drugs.

Pharmacological actions

  • Anti-Inflammatory Agents, Non-Steroidal
  • Immunosuppressive Agents

Roles

  • analgesic
  • anti-inflammatory agent
  • anti-inflammatory drug
  • antipyretic
  • antirheumatic drug
  • apoptosis inhibitor
  • enzyme inhibitor
  • immunomodulator
  • lipoxygenase inhibitor
  • non-narcotic analgesic
  • non-steroidal anti-inflammatory drug
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Tepoxalin is traded under.

HS 2933.19Indicative HS code

Compounds containing an unfused pyrazole ring (whether or not hydrogenated) in theโ€ฆ

World exports in 2024
$3.44B
โˆ’22.6% vs 2023, imports $6.66B
2019 to 2024
Top exporters
  1. China21.6%
  2. Switzerland * partner reported20.5%
  3. Germany19.0%
Top importers
  1. Slovenia38.4%
  2. Portugal14.1%
  3. Brazil13.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Tepoxalin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Tepoxalin, based on the data on this page

What is Tepoxalin?

Tepoxalin is a hydroxamic acid obtained by formal condensation of the carboxy group of 3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl]propanoic acid with the amino group of N-methylhydroxylamine.

What is the CAS number of Tepoxalin?

The CAS registry number of Tepoxalin is 103475-41-8.

What is the molecular formula and weight of Tepoxalin?

The molecular formula of Tepoxalin is C20H20ClN3O3 and its molar mass is 385.85 g/mol.

What is Tepoxalin used for?

Use classes: Animal Drugs.

Is Tepoxalin hazardous?

Tepoxalin carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Tepoxalin?

Tepoxalin is usually classified under HS code 293319 (Compounds containing an unfused pyrazole ring (whether or not hydrogenated) in theโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Tepoxalin?

CompoundList lists 5 suppliers of Tepoxalin in China and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Tepoxalin?

Suppliers quote Tepoxalin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Tepoxalin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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