Tepoxalin
Also known as Tepoxaline, Zubrin, ORF 20485
Key facts
What buyers check first
- CAS number
- 103475-41-8
- Formula
- C20H20ClN3O3
- Molar mass
- 385.85 g/mol
- EC number
- 638-877-2
- HS code
- 293319
- Category
- Analgesics and anti-inflammatories
What is Tepoxalin?
Plain description, key identifiers and synonyms
Tepoxalin is a hydroxamic acid obtained by formal condensation of the carboxy group of 3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl]propanoic acid with the amino group of N-methylhydroxylamine. It is used in veterinary medicine for the control of pain and inflammation caused by musculoskeletal disorders such as hip dysplasia and arthritis in dogs. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, an antipyretic, an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor, a lipoxygenase inhibitor, an immunomodulator and an apoptosis inhibitor. It is a hydroxamic acid, a member of pyrazoles, an aromatic ether and a member of monochlorobenzenes.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl]-N-hydroxy-N-methylpropanamide
- CAS number
- 103475-41-8 CAS number cross-checked
- EC number
- 638-877-2
- Molecular formula
- C20H20ClN3O3
- UNII
- TZ4OX61974
- MDL number
- MFCD00866620
- InChIKey
- XYKWNRUXCOIMFZ-UHFFFAOYSA-N
- InChI
- InChI=1S/C20H20ClN3O3/c1-23(26)20(25)12-7-16-13-19(14-3-5-15(21)6-4-14)24(22-16)17-8-10-18(27-2)11-9-17/h3-6,8-11,13,26H,7,12H2,1-2H3
- SMILES (canonical and isomeric)
- CN(C(=O)CCC1=NN(C(=C1)C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)OC)O
Synonyms
- Tepoxaline
- Zubrin
- ORF 20485
- Tepoxalina
- RWJ 20485
- Tepoxalinum
- 5-(4-Chlorophenyl)-N-hydroxy-1-(4-methoxyphenyl)-N-methyl-1H-pyrazole-3-propanamide
- 5-(p-Chlorophenyl)-1-(p-methoxyphenyl)-N-methylpyrazole-3-propionohydroxamic acid
- 1H-Pyrazole-3-propanamide, 5-(4-chlorophenyl)-N-hydroxy-1-(4-methoxyphenyl)-N-methyl-
- 3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl]-N-hydroxy-N-methylpropanamide
- Zubrin Rapidly-Disintegrating Tablets
- 3-(5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl)-N-hydroxy-N-methylpropanamide
- Tepoxalin (USAN/INN)
- 3-(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-1H-pyrazol-3-yl)-N-hydroxy-N-methylpropanamide
- 3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)-1H-pyrazol-3-yl]-N-hydroxy-N-methylpropanamide
- 3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl]-N-hydroxy-N-methyl-propanamide
- C20H20ClN3O3
- tepoxaliume
- 3-(5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-pyrazolyl)-N-hydroxy-N-methylpropanamide
- Tepoxalin Solution in Methanol, 100ug/mL
- 3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyrazol-3-yl]-N-hydroxy-N-methyl-propionamide
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 385.85 g/molcalc.Computed value |
|---|---|
| Exact mass | 385.1193 Dacalc.Computed value |
| LogP (octanol/water) | 3.98calc.Computed value |
| Topological polar surface area | 67.59 ร
ยฒcalc.Computed value |
| Hydrogen bond donors | 1calc.Computed value |
| Hydrogen bond acceptors | 4calc.Computed value |
| Rotatable bonds | 6calc.Computed value |
| Heavy atoms | 27calc.Computed value |
| Rings | 3calc.Computed value |
| Aromatic rings | 3calc.Computed value |
| Fraction sp3 carbons | 0.2calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
c1ccc(-c2ccnn2-c2ccccc2)cc1
3 rings, 17 atoms, the 1,5-Diphenyl-1H-pyrazole ring system.
451 other chemicals share this scaffoldSafety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H302Harmful if swallowed.
Precautionary statements (5)
- P264Wash skin thoroughly after handling.
- P270Do not eat, drink or smoke when using this product.
- P301 + P317If swallowed: Get medical help.
- P330Rinse mouth.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidTepoxalin suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- China ManufacturerUnclaimed profileTepoxalinGrade, purity and minimum order on requestPrice on request
- China, WuhanUnclaimed profileTepoxalinGrade, purity and minimum order on requestPrice on request
- China, GuangzhouUnclaimed profileTepoxalinGrade, purity and minimum order on requestPrice on request
- United States, HopkintonUnclaimed profileTepoxalinGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
5 suppliers in 2 countries
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Tepoxalin price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Use classes: Animal Drugs.
Industries and functions
Pharmacological actions
- Anti-Inflammatory Agents, Non-Steroidal
- Immunosuppressive Agents
Roles
- analgesic
- anti-inflammatory agent
- anti-inflammatory drug
- antipyretic
- antirheumatic drug
- apoptosis inhibitor
- enzyme inhibitor
- immunomodulator
- lipoxygenase inhibitor
- non-narcotic analgesic
- non-steroidal anti-inflammatory drug
- pharmaceutical
Regulatory status
Inventories, regulations and trade controls that list this substance
No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Tepoxalin is traded under.
Compounds containing an unfused pyrazole ring (whether or not hydrogenated) in theโฆ
- China21.6%
- Switzerland * partner reported20.5%
- Germany19.0%
* Partner reported figures, a lower bound.
The HS code shown for Tepoxalin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Tepoxalin, based on the data on this page
What is Tepoxalin?
What is the CAS number of Tepoxalin?
What is the molecular formula and weight of Tepoxalin?
What is Tepoxalin used for?
Is Tepoxalin hazardous?
What is the HS code of Tepoxalin?
Where can I buy Tepoxalin?
What is the price of Tepoxalin?
Guides for buyers
Practical guides that help when you source, ship or handle Tepoxalin
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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