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Food and feed additives

Thiodipropionic acid

Also known as 3,3'-Thiodipropionic acid, Tyox A, TDPA

CAS 111-17-1Formula C6H10O4SMolar mass 178.21 g/molEC 203-841-3
GHS signal word: Danger. Pictograms: Corrosive, Harmful or irritant 13 suppliers listed
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Thiodipropionic acid chemical structure, C6H10O4S, CAS 111-17-1
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Nacreous leaflets from hot water
Melting point
134 °C
Solubility
FREELY SOL IN HOT WATER, ALC, ACETONE, 1 G DISSOLVES IN 26.9 ML WATER @ 26 °C
HS code
293090
Category
Food and feed additives
Illustrative photo, closed blue fibre drums on a pallet in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Thiodipropionic acid?

Plain description, key identifiers and synonyms

3,3'-Thiobispropanoic acid is a dicarboxylic acid.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-(2-carboxyethylsulfanyl)propanoic acid
CAS number
111-17-1 CAS number cross-checked
EC number
203-841-3
Molecular formula
C6H10O4S
UNII
3BBK323ED8
MDL number
MFCD00002781
INCI name
THIODIPROPIONIC ACID
InChIKey
ODJQKYXPKWQWNK-UHFFFAOYSA-N
InChI
InChI=1S/C6H10O4S/c7-5(8)1-3-11-4-2-6(9)10/h1-4H2,(H,7,8)(H,9,10)
SMILES (canonical and isomeric)
C(CSCCC(=O)O)C(=O)O

Synonyms

  • 3,3'-Thiodipropionic acid
  • Tyox A
  • TDPA
  • Propanoic acid, 3,3'-thiobis-
  • Bis(2-carboxyethyl) sulfide
  • Thiodihydracrylic acid
  • 4-Thiaheptanedioic acid
  • Sulfide, bis(2-carboxyethyl)
  • 3,3'-Thiobis(propanoic acid)
  • Thiahydracrylic acid
  • Propionic acid, 3,3'-thiodi-
  • Diethyl sulfide 2,2'-dicarboxylic acid
  • Kyselina beta,beta'-thiodipropionova
  • 3,3'-Thiodipropanoic acid
  • 3,3-thiodipropionic acid
  • 3-[(2-carboxyethyl)sulfanyl]propanoic acid
  • 3,3'-Thiodi(propionic acid)
  • 3-(2-carboxyethylsulfanyl)propanoic acid
  • 3,3'-Thiobispropanoic acid
  • Kyselina 3,3-thiodipropionova
  • 3,3-Thiodipropionicacid
  • beta,beta'-Thiodipropionic acid
  • 3,3'-Thiobis-propanoic acid
  • Diethyl sulfide-2,2'-dicarboxylic acid
  • 3,3 inverted exclamation mark(R)-Thiodipropionic acid
Show all 34 synonyms
  • 3-(2-carboxyethylthio)propanoic acid
  • Thiobispropanoic acid
  • 4-Thiaheptanedioio acid
  • Propionic acid,3'-thiodi-
  • Propanoic acid,3'-thiobis-
  • 3,3\'-Thiodipropionic acid
  • 3,3'-Thiodi-Propionic acid
  • 3,3'-Thi
  • INS NO.388

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Nacreous leaflets from hot waterexp.
Melting point
134 °Cexp.
Solubility
FREELY SOL IN HOT WATER, ALC, ACETONE, 1 G DISSOLVES IN 26.9 ML WATER @ 26 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
178.21 g/molcalc.
Exact mass
178.03 Dacalc.
LogP (octanol/water)
0.67calc.
Topological polar surface area
74.6 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
6calc.
Heavy atoms
11calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.67calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS05: Corrosive
Corrosive
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H318Causes serious eye damage.
  • H319Causes serious eye irritation.
Precautionary statements (6)
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Thiodipropionic acid suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 13 suppliers
13 of 13 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

13 suppliers in 5 countries

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Thiodipropionic acid price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Antioxidant for soap products & polymers of ethylene, in plasticizers and lubricants.

Preservative & antioxidant for edible fats & oils, pharmaceuticals, food packaging ingredient.

Industrial uses: Stabilizing agent, Monomers.

Consumer uses: Stabilizing agent.

Cosmetic ingredient, INCI name THIODIPROPIONIC ACID(skin conditioning)

Functional uses

  • Antioxidant
  • Catalyst
  • Softener and conditioner

Cosmetic functions

  • Skin conditioning

How it is made

British patent 571,628 (1945 to am cyanamid co), gresham, shaver, us patent 2,449,992 (1948 to bf goodrich).

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Thiodipropionic acid is traded under.

HS 2930.90Indicative HS code

Organo-sulphur compounds, other

World exports in 2024
$5.83B
+0.1% vs 2023, imports $5.93B
2019 to 2024
Top exporters
  1. China40.7%
  2. United States10.9%
  3. Japan9.3%
Top importers
  1. United States13.3%
  2. Brazil12.6%
  3. China6.6%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Thiodipropionic acid is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Thiodipropionic acid, based on the data on this page

What is Thiodipropionic acid?

3,3'-Thiobispropanoic acid is a dicarboxylic acid.

What is the CAS number of Thiodipropionic acid?

The CAS registry number of Thiodipropionic acid is 111-17-1.

What is the molecular formula and weight of Thiodipropionic acid?

The molecular formula of Thiodipropionic acid is C6H10O4S and its molar mass is 178.21 g/mol.

What is Thiodipropionic acid used for?

Antioxidant for soap products & polymers of ethylene, in plasticizers and lubricants. Preservative & antioxidant for edible fats & oils, pharmaceuticals, food packaging ingredient. Industrial uses: Stabilizing agent, Monomers. Consumer uses: Stabilizing agent.

Is Thiodipropionic acid hazardous?

Thiodipropionic acid carries the GHS signal word "Danger". Main hazards: causes serious eye damage, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Thiodipropionic acid?

Thiodipropionic acid is usually classified under HS code 293090 (Organo-sulphur compounds, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Thiodipropionic acid?

CompoundList lists 13 suppliers of Thiodipropionic acid in China, Germany, United States, Canada and 1 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Thiodipropionic acid?

Suppliers quote Thiodipropionic acid on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Thiodipropionic acid

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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