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Hair care agents

Thioglycerol

Also known as 3-Mercapto-1,2-propanediol, 1-Thioglycerol, Monothioglycerol

CAS 96-27-5Formula C3H8O2SMolar mass 108.16 g/molEC 202-495-0
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Harmful or irritant 29 suppliers listed
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Thioglycerol chemical structure, C3H8O2S, CAS 96-27-5
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Yellowish, very viscous liquid
Boiling point
118 °C
Density
1.295
Solubility
SLIGHTLY SOL IN WATER, MISCIBLE WITH ALCOHOL, INSOL IN ETHER
HS code
293090
Category
Hair care agents
Illustrative photo, amber viscous resin in a steel drum in a chemical plant
Typical packagingIllustrative packaging image, not the actual product

What is Thioglycerol?

Plain description, key identifiers and synonyms

Monothioglycerol is a thiol that is glycerol in which one of the primary hydroxy groups is replaced by a thiol group. It has a role as a reducing agent and a vulnerary. It is a member of propane-1,2-diols and a thiol.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-sulfanylpropane-1,2-diol
CAS number
96-27-5 CAS number cross-checked
EC number
202-495-0
Molecular formula
C3H8O2S
UNII
AAO1P0WSXJ
MDL number
MFCD00004879
INCI name
THIOGLYCERIN
InChIKey
PJUIMOJAAPLTRJ-UHFFFAOYSA-N
InChI
InChI=1S/C3H8O2S/c4-1-3(5)2-6/h3-6H,1-2H2
SMILES (canonical and isomeric)
C(C(CS)O)O

Synonyms

  • 3-Mercapto-1,2-propanediol
  • 1-Thioglycerol
  • Monothioglycerol
  • Thioglycerin
  • Thiovanol
  • alpha-Thioglycerol
  • Thioglycerine
  • Glycerol-1-thiol
  • 1-Mercaptoglycerol
  • 1-Monothioglycerol
  • 1,2-Propanediol, 3-mercapto-
  • Monothioglycerin
  • 2,3-Dihydroxypropanethiol
  • 1-Mercapto-2,3-propanediol
  • alpha-Thiolglycerol
  • Glycerol, 1-thio-
  • alpha-Monothioglycerol
  • 1-Thio-2,3-propanediol
  • USAF CB-37
  • USAF B-40
  • mercaptoglycerol
  • GlyTouCan:G07756TT
  • 3-Mercaptopropane-1,2-diol
  • 3-Sulfanylpropane-1,2-diol
  • 3-Mercapto-1,2-propanediole
Show all 31 synonyms
  • Monothioglycerol (NF)
  • DL-1-Thioglycerol
  • 3-Mercapto-propane-1,2-diol
  • 1-Thio-DL-glycerol
  • 1, 3-mercapto-
  • 1-Thioglycerol, >=97%

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Yellowish, very viscous liquidexp.
Odour
SLIGHT SULFIDICexp.
Boiling point
118 °Cexp.
Density
1.295exp.
Solubility
SLIGHTLY SOL IN WATER, MISCIBLE WITH ALCOHOL, INSOL IN ETHERexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
108.16 g/molcalc.
Exact mass
108.0245 Dacalc.
LogP (octanol/water)
-0.73calc.
Topological polar surface area
40.46 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
2calc.
Heavy atoms
6calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H311Toxic in contact with skin.
  • H315Causes skin irritation.
  • H317May cause an allergic skin reaction.
  • H319Causes serious eye irritation.
  • H331Toxic if inhaled.
  • H335May cause respiratory irritation.
Precautionary statements (24)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P262Do not get in eyes, on skin, or on clothing.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P316Get emergency medical help immediately.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Thioglycerol suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 29 suppliers
29 of 29 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

29 suppliers in 7 countries

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Thioglycerol price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

In wound healing, vet: to promote wound healing (solution 1:5000).

Pharmaceutic aid (preservative).

Reducing agent for cystine molecule in human hair & wool, for stabilization of acrylonitrile polymers.

Industrial uses: Preservative.

Consumer uses: Stabilizing agent.

Use classes: Cosmetics.

Cosmetic ingredient, INCI name THIOGLYCERIN(depilatory, hair waving or straightening, keratolytic, reducing)

Roles

  • pharmaceutical
  • reducing agent
  • vulnerary

Functional uses

  • Depilatory
  • Hair waving or straightening
  • Heat stabilizer
  • Pharmaceutical
  • Reducing agent

Cosmetic functions

  • Depilatory
  • Hair waving or straightening
  • Keratolytic
  • Reducing

How it is made

Prepd by heating glycerol-alpha-monochlorohydrin with khs in alcoholic solution. Sutton, j am med assoc 104, 2168 (1935).

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Thioglycerol is traded under.

HS 2930.90Indicative HS code

Organo-sulphur compounds, other

World exports in 2024
$5.83B
+0.1% vs 2023, imports $5.93B
2019 to 2024
Top exporters
  1. China40.7%
  2. United States10.9%
  3. Japan9.3%
Top importers
  1. United States13.3%
  2. Brazil12.6%
  3. China6.6%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Thioglycerol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Thioglycerol, based on the data on this page

What is Thioglycerol?

Monothioglycerol is a thiol that is glycerol in which one of the primary hydroxy groups is replaced by a thiol group. It has a role as a reducing agent and a vulnerary. It is a member of propane-1,2-diols and a thiol.

What is the CAS number of Thioglycerol?

The CAS registry number of Thioglycerol is 96-27-5.

What is the molecular formula and weight of Thioglycerol?

The molecular formula of Thioglycerol is C3H8O2S and its molar mass is 108.16 g/mol.

What is Thioglycerol used for?

In wound healing, vet: to promote wound healing (solution 1:5000). Pharmaceutic aid (preservative). Reducing agent for cystine molecule in human hair & wool, for stabilization of acrylonitrile polymers. Industrial uses: Preservative. Consumer uses: Stabilizing agent. Use classes: Cosmetics.

Is Thioglycerol hazardous?

Thioglycerol carries the GHS signal word "Danger". Main hazards: harmful if swallowed, toxic in contact with skin, causes skin irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Thioglycerol?

Thioglycerol is usually classified under HS code 293090 (Organo-sulphur compounds, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Thioglycerol?

CompoundList lists 29 suppliers of Thioglycerol in India, United States, China, Germany and 3 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Thioglycerol in India?

9 suppliers in India list Thioglycerol on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Thioglycerol?

Suppliers quote Thioglycerol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Thioglycerol

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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